Clinical trials: Weight Loss, completed
Early Stage Breast Cancer
POWER-remote Weight Loss Program in Early Stage Breast Cancer
This research is being done to assess the effectiveness of a weight loss program in women with early stage breast cancer whose body mass index (BMI) is in the overweight or obese range (>25).
- Trial name
- NCT01871116
- Testing
- POWER-remote, Self-directed
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Chronic Pain, Obesity
A Mobile Intervention to Reduce Pain and Improve Health (MORPH)
Chronic pain contributes to declining health and function in older adults; effects that are intensified by obesity and sedentary (sitting) behavior.
- Conditions
- Chronic Pain, Obesity, Sedentary Lifestyle
- Trial name
- NCT03377634
- Testing
- MORPH
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Wake Forest University Health Sciences
Obesity, Overweight
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable…
- Trial name
- NCT06584916
- Testing
- Orforglipron
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 376 people
- Sponsor
- Eli Lilly and Company
Overweight, Obesity
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
Dietary protein is a key element of most effective weight loss regimens. This study will investigate the effects of consuming soy protein on body composition and cardiometabolic health within the context of an effective weight…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- NCT02380963
- Testing
- Colorado Diet with soy protein foods., Colorado Diet with monetary payments
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- DuPont Nutrition and Health
Physical Activity, Obesity
Feelings About Exercise
This study seeks to investigate why some individuals exercise more than others by focusing on feelings related to exercise. This two part study first examines whether regular exercisers (n=30) and non-exercisers (n=30) differ in…
- Trial name
- NCT03598647
- Testing
- Affect and physical activity, Physical activity information
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity, Sub Fertility, Male
Weight Loss Impact on Male Fertility
This is a prospective non-randomized unicentric clinical trial, characterized by the inclusion of obese (BMI> 35) male with subfertility (sperm count showing low sperm counts and / or motility and / or morphology and / or DNA…
- Conditions
- Obesity, Sub Fertility, Male, Metabolic Syndrome
- Trial name
- NCT04186767
- Testing
- Very Low Carb Ketogenic Diet
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo
Obesity & Overweight, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)
Adherence and Tolerability of Four Very Low-Calorie Ketogenic Diet Approaches in Adults With Obesity or Complicated Overweight
This study, called KOBE Study, looks at how well different very low-calorie ketogenic diets (VLCKD) are followed and tolerated by adults with obesity or complicated overweight in routine clinical practice.
- Conditions
- Obesity & Overweight, MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis), Type 2 Diabetes, Insulin Resistance
- Trial name
- KOBE (NCT07389122)
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- University of Bologna
Breast Cancer, Weight Loss
Effectiveness of a Combined Diet and Mindfulness Program on Weight Loss in Breast Cancer Survivors
The study addresses the pressing issue of overweight and obesity among breast cancer patients, which exacerbates recurrence rates and mortality risks.
- Trial name
- NCT06427473
- Testing
- Dietary program, Exercise program, Mindfulness program
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- National Yang Ming Chiao Tung University
Chronic Kidney Diseases, Obesity
Intermittent Low Energy Diet in CKD: MIX UP Feasibility Study
This study proposes to investigate the acceptability and efficacy of intermittent VLED (5:2 diet) plus exercise, compared with the investigator's established Weight Management Programme (WMP), in obese patients with CKD, using…
- Trial name
- MIX-UP (NCT03736551)
- Testing
- 5:2 diet, Renal Weight Management Programme
- Where
- United Kingdom
- Volunteers
- 13 people
- Sponsor
- King's College Hospital NHS Trust
Diet Quality, Weight Loss
Alternative Dietary Approaches Online to Promote Tracking
Purpose: Compare the efficacy of two 3-month Internet-based interventions that use a simplified strategy for monitoring of dietary intake among young adult men and women with overweight or obesity.
- Trial name
- ADOPT (NCT05049005)
- Testing
- Simplified dietary tracking
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Overweight and Obesity
Weight Reduction With the Low-Insulin-Method
Background: Overweight and obesity affect health, quality of life and ability to work. Therefore, the Low-Insulin-Method was developed to support overweight and obese people in weight loss.
- Trial name
- WeR-LIM (NCT05933759)
- Testing
- Telemedical coaching, Low-Insulin-Method
- Where
- Germany
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- West German Center of Diabetes and Health
Weight Loss
VK2735 for Weight Management Phase 2
This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of VK2735 in adults who…
- Trial name
- VENTURE (NCT06068946)
- Testing
- VK2735
- Where
- 20 sites in United States
- Volunteers
- 176 people
- Sponsor
- Viking Therapeutics, Inc.
Weight Loss
The Leeds Women's Wellbeing (LWW) Study
The purpose of this parallel design study is to assess the relative effects of two 12-week healthy eating dietary interventions: general healthy eating (Diet A) and general healthy eating combined with advice to increase fibre…
- Trial name
- LWW (NCT01539369)
- Testing
- Healthy eating diet (Diet A) or healthy eating diet combined with advice to increase fibre intake (Diet B) to at least 25g/day
- Where
- United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity, Weight Loss
Effects of Physical Activity on Weight Loss and Weight Maintenance in Obese Adults - Three Year Follow-up Study
Objective To study if exercise added to weight loss treatment at the beginning of the weight loss intervention or at 6 months could sustain the weight loss achieved or give extra boost for weight reduction.
- Conditions
- Obesity, Weight Loss, Physical Activity, Healthy Obesity, Metabolically
- Trial name
- LILA (NCT03861754)
- Testing
- Lifestyle modification
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- University of Oulu
Cancer, Cancer Cachexia
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
The purpose of this study is to evaluate the safety and effectiveness of fish oil supplements in maintaining weight in people with disease-related weight loss and/or cachexia.
- Conditions
- Cancer, Cancer Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00094562
- Testing
- Fish oil supplement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Obesity
Evaluation of the Shape Up Rhode Island Campaign Study 5
Obesity is a major health problem that has reached epidemic levels. Efforts are needed to develop cost-effective public health approaches for weight loss and maintenance.
- Trial name
- NCT00948415
- Testing
- Evaluation of the Shape Up RI Campaign
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Body Weight, Body Image
WFPB Lifestyle and Muscle Mass Preservation
Body fat (BF) and muscle mass showed opposing association with mortality. Whole-food, plant-based (WFPB) lifestyle programs has been on the rise lately especially due to impressive health benefits.
- Conditions
- Body Weight, Body Image, Body Weight Changes, Muscle Loss
- Trial name
- WFPBmuscle (NCT04849689)
- Testing
- Whole-food, plant-based lifestyle
- Where
- Slovenia
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Obesity, Overweight
A Maintenance Program for the Be Fit Employee Wellness Program
This research study is being done: 1) to determine if the MGH Be Fit program helps employees to change their nutrition and exercise habits and lower their risk for chronic diseases, such as heart disease and diabetes and 2) to…
- Trial name
- NCT00707577
- Testing
- Internet-based maintenance program
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Alzheimer's Disease, Dementia
Nutritional Programme for Dementia Elderly Patient
The main objective of this study is the improvement of the quality of life and state of health of elderly people with cognitive deterioration and their families through a weight loss prevention programme.
- Trial name
- NCT00479843
- Testing
- Nutritional programme
- Where
- Spain
- Volunteers
- 946 people
- Sponsor
- Société des Produits Nestlé (SPN)
Trans Epidermal Water Loss
Effect of Twice Daily Application of Coconut Oil in Reducing Water Loss From Skin of Premature Babies in First Week of Life
The skin of newborn infants is immature and ineffective as a barrier. Preterm skin exhibits even more vulnerability to the environment due to poor self regulatory heat mechanisms, paucity of fatty tissue and its thinness.
- Trial name
- TEWL (NCT01758068)
- Testing
- Coconut Oil Application
- Volunteers
- 74 people
- Sponsor
- Lady Hardinge Medical College
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