Clinical trials: Weight Loss, completed
Obesity
Effect of Wholegrain Wheat on Body Weight and Composition and Cardiovascular Risk
The aim of this study is to investigate the potential beneficial effect of wholegrain on body weight and composition as well as cardiovascular risk in overweight women.
- Trial name
- HEALTHGRAIN (NCT00869531)
- Testing
- wholegrain, refined wheat
- Where
- Denmark
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Metabolic Syndrome
Intensive Lifestyle Intervention for Remission of Metabolic Syndrome
This is a randomized, prospective clinical trial investigating metabolic syndrome in overweight or obese Chinese individuals. The study aims to evaluate the efficacy of a structured intensive lifestyle intervention program in…
- Trial name
- INSLIMS (NCT04116905)
- Testing
- Intensive Lifestyle Intervention, Conventional Treatment
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Bariatric Surgery, Metabolic Surgery
Comparative Effectiveness of Metabolic and Bariatric Surgery With PROMs
This long-term, nationwide observational data collection repository will obtain patient-reported outcomes from metabolic and bariatric surgery patients.
- Conditions
- Bariatric Surgery, Metabolic Surgery, Weight Reduction
- Trial name
- MBSAQIP-PROM (NCT02749305)
- Testing
- Collection of patient-reported outcome measures
- Where
- United States
- Volunteers
- 11,146 people
- Sponsor
- Massachusetts General Hospital
Weight Loss, Other Effects of High Altitude
Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization
This research will evaluate nutrition requirements for missions at high altitude (i.e. >7800 feet above sea level) and the information obtained can be used to optimize nutrient content specifications for combat rations.
- Trial name
- NCT02731066
- Testing
- Standard pro, High pro, carbo bev
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Abdominal Obesity, Metabolic Syndrome
Diet, Exercise, Metabolism, and Obesity in Older Women
Reductions in fat oxidation and resting metabolic rate (RMR) are associated with normal aging and are accelerated with menopause.
- Trial name
- DEMO (NCT00664729)
- Testing
- Caloric Restriction, Caloric Restriction + Low-Intensity aerobic exercise, Caloric Restriction plus High-intensity aerobic exercise
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Overweight
A Study of Weekly Oral Ecnoglutide (VRB-101) in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
The aim of this study is to evaluate the efficacy of VRB-101 for body weight reduction compared to placebo in participants who have obesity or overweight with weight-related comorbidities.
- Trial name
- EVOLVE-2 (NCT07281937)
- Testing
- VRB-101
- Where
- 22 sites in United States
- Volunteers
- 206 people
- Sponsor
- Verdiva Bio Dev Limited
Overweight
Caloric Restriction and Body Weight in Adults
The purpose of this study is to determine the role of 1. dietary calcium in fecal fat loss and the association between lactose maldigestion, dietary calcium level and source, and weight loss induced by caloric restriction. 2.
- Trial name
- NCT00808275
- Testing
- Dietary calcium
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Obesity, Inflammation
Gene Expression and Inflammation in Overweight Subjects
This study will look at gene expression (whether particular sets of genes are activated ["turned on"] or deactivated ["turned off"]) in overweight people as compared to non-overweight individuals.
- Conditions
- Obesity, Inflammation, Nutrition Therapy
- Trial name
- NCT00344266
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Colorectal Tumor
Study of the Relationship Between Clinical and Paraclinical Markers During Situations of Cachexia and Pre-cachexia in Patients Over 70 Years With Colorectal Surgery
Cachexia associated with cancer is a grave and most of the time irreversible common situation. It seems independent from the size of the tumor or from its metastatic character.
- Trial name
- ANC2 (NCT02199912)
- Testing
- Biopsy of adipose and muscular tissue, Blood sampling, Calorimetry
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Obesity
Personalized Nutrition and eHealth: Lifestyle Intervention (LION) Study for Weight Loss Maintenance
Despite standardized intervention strategies, weight loss and weight loss maintenance largely differ from person to person. Factors which may contribute to these individual differences is current object of research.
- Trial name
- LION (NCT04023942)
- Testing
- Weight maintenance intervention
- Where
- Germany
- Volunteers
- 272 people
- Sponsor
- Technical University of Munich
Obesity, Overweight
Calcium Supplementation for a Healthy Weight-Lite (CaSHeW Lite)
The purpose of the study is to find out if taking calcium and vitamin D supplements, while following a low-calorie diet, can help people lose weight.
- Trial name
- NCT00386672
- Testing
- Reduced energy (lite) OJ fortified with Calcium and Vitamin D, Nutrition Counseling, Reduced energy (lite) OJ without Calcium and Vitamin D
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Obesity, Type 2 Diabetes
Stress, Dietary Lapse and Weight Loss Among Adults With Type 2 Diabetes
A clinical trial that uses personal digital assistants (PDAs) to assist in examining the relationship between self reported stress, an objective biochemical indicator of stress (salivary alpha amylase) and self-reported dietary…
- Trial name
- NCT00831194
- Testing
- Personalized diet plan and PDA self reporting.
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Obesity
Impact of Weight Loss on Physical Function
We are proposing a trial to directly compare a high intensity weight loss protocol to a moderate intensity weight loss protocol to determine which leads to greater improvements in physical function in severely obese older adults.
- Trial name
- OPTIFAST (NCT02079051)
- Testing
- Moderate intensity weight loss, High intensity medical weight loss
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Premenstrual Syndrome
Effect of Weight Reduction and Aerobic Exercise on PMS Symptoms in Obese Females
The purpose of this study will be investigation of the effect of weight reduction and aerobic exercises on premenstrual syndrome symptoms in obese females.
- Trial name
- PMS (NCT05707845)
- Testing
- Medical treatment., weight reduction, exercise
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Childhood Obesity, NAFLD (Non-alcoholic Fatty Liver Disease)
Metabolic Syndrome and Gen-polymorphs Influence on Weightloss Among Children in Treatment for Overweight
Definition: the overall objective is to examine childhood obesity with focus on NAFLD and its treatment. Further, we aimed to investigate the impact of genetic variation on obesity.
- Conditions
- Childhood Obesity, NAFLD (Non-alcoholic Fatty Liver Disease), Hypertension, Hyperlipidemia
- Trial name
- NCT00823277
- Testing
- Chronic care multidisciplinary intervention of childhood obesity
- Where
- Denmark
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Obesity, Eating Disorders
Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to reduce binge eating and improve healthy weight regulation skills will result in reductions in binge eating and weight loss, or weight…
- Trial name
- NCT00125112
- Testing
- Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Pilot Study of the Effect of Liraglutide 3.0 mg on Weight Loss and Gastric Functions in Obesity
This study is being done to assess the stomach emptying effect of a maximum dose of 3 mg Liraglutide compared to placebo in subjects who are overweight or obese.
- Trial name
- NCT03523273
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Michael Camilleri, MD
Mental Health Wellness 1, Depression, Anxiety
Mental Health in Fitness Instructors
The aim of this project is to improve the evidence-base regarding lifestyle and mental health symptoms among fitness instructors.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety, Eating Disorders, Eating Behavior
- Trial name
- NCT04135729
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- Norwegian School of Sport Sciences
Obstructive Sleep Apnea
Lifestyle Intervention for OSA in Adults
Obstructive sleep apnoea (OSA) is characterized by the presence in the polysomnogram test of more than five apnoea-hypopnoea episodes per hour of sleep (apnoea-hypopnoea index, AHI > 5), each episode lasting more than 10 seconds…
- Trial name
- NCT03851653
- Testing
- Lifestyle Intervention
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- Universidad de Granada
Obesity, Behavior, Health
Evaluation of Brain Activity Changes After a Behavior Change Weight Loss Intervention
The aim of this study is to compare brain changes in individuals with overweight or obesity enrolled in either the Noom Healthy Weight program or a matched control.
- Conditions
- Obesity, Behavior, Health, Weight Loss
- Trial name
- NCT04522245
- Testing
- Noom Healthy Weight; mobile behavior change program for weight loss., Matched Control
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Noom Inc.
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