Clinical trials: Weight Loss, completed
Obesity
DVD Lifestyle Intervention
Most Veterans who receive VA healthcare have obesity (41%) or are classified as overweight (37%), putting them at higher risk for multiple serious chronic health conditions.
- Trial name
- D-ELITE (NCT03260140)
- Testing
- behavioral lifestyle intervention
- Where
- United States
- Volunteers
- 511 people
- Sponsor
- VA Office of Research and Development
Obesity
Comparison of 1 vs 3 Sets of Resistance Training on Muscular Hypertrophy
This study is designed to investigate the effects of two levels of resistance weight training on body composition, energy expenditure, and energy intake in men and women. The weight training will take about one hour to complete.
- Trial name
- NCT01107691
- Testing
- Amount of resistance offered in training
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Diet, Reducing
Calorie Restriction Diets on Weight Reduction, Post weigh-in Recovery and Exercise Performance in Athletes
Low-carbohydrate diets are often used as weight-loss strategies by obese individuals and athletes. This diet has effects on oxidizing fat and suppressing appetite. But short term evidences are still few.
- Trial name
- NCT05017259
- Testing
- calorie restriction diet
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chin Hsu
Pulmonary Tuberculosis, Body Weight Changes
Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia
Tuberculosis (TB) patients often have a lower body mass index (BMI) and experience wasting. Wasting reduces lean body mass and may cause physical function impairment.
- Conditions
- Pulmonary Tuberculosis, Body Weight Changes, Motor Activity
- Trial name
- FSS (NCT02554318)
- Testing
- Rifampicin, Isoniazid, Pyrazinamide
- Volunteers
- 147 people
- Sponsor
- University of Giessen
Obesity
Study on Mechanisms of Changes in Liver Disease and Sex Steroid Metabolism During Weight Loss
The main objective of the study is to gain insight in the early dynamics and mechanisms of recovery of liver disease and sex steroid metabolism during weight loss in obese men and women and to investigate whether surgical weight…
- Trial name
- SMELSS (NCT02964780)
- Testing
- Gastric bypass surgery, Conservative weight loss program
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- University Ghent
Obesity
Evaluation of Liver Fibrosis Following Surgical-induced Weight Loss
Obesity is a frequent disease with an increased prevalence, estimated to 12.4% in France (OBEPI study 2006). Non alcoholic fatty liver disease (NAFLD) and non alcoholic steatohepatitis (NASH) both complicate morbid obesity and…
- Trial name
- FIBROTEST (NCT01469962)
- Testing
- Surgical procedure
- Where
- France
- Volunteers
- 255 people
- Sponsor
- University Hospital, Rouen
Pediatric Obesity
Factors Associated With Changes in Weight-status in Danish School Children With Obesity
Childhood obesity is increasing worldwide and causes a major health concern. Only limited insight exists into the natural history of childhood obesity at children already classified as obese.
- Trial name
- NCT06077266
- Testing
- Change of weight class to normal weight
- Where
- Denmark
- Volunteers
- 467 people
- Sponsor
- University of Aarhus
Obesity
The Effects of Oxytocin in Obese Adults
This is a randomized, double blind, placebo-controlled study of the effects of intranasal oxytocin in obese adults, ages 18-45 years old.
- Trial name
- NCT03043053
- Testing
- oxytocin nasal spray
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Massachusetts General Hospital
Polycystic Ovary Syndrome, Overweight and Obesity
Weight Loss Intervention in Women With PCOS
The proposed single arm 6 mo. trial will assess the impact of weight loss and fat loss due to a multicomponent remotely-delivered lifestyle intervention on ovulation rates and time-to-ovulation in overweight and obese women with…
- Trial name
- NCT03677362
- Testing
- Weight loss intervention
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Kansas Medical Center
Weight Loss, Obesity
Noom Health for Weight Management
The goals of the study are to use the Noom mobile app to help individuals with weight loss and weight loss maintenance. This project will test the comparative efficacy of Noom Health vs.
- Trial name
- NCT04797169
- Testing
- Noom Health, Noom Digital Health
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Overweight and Obesity, Chronic Disease
Influence of Genetic and Physiological in Weight Loss
The study focuses on the influence of polymorphism in the FTO genes rs9939609 and PPARᵧ Pro12Ala, oxidative stress and systemic inflammation on changes in body composition and rest metabolism induced by HIIT and continuous…
- Trial name
- NCT03568773
- Testing
- High-intensity interval training, Aerobic exercise moderate intensity, Control Group
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Obesity
Eat Well for Life: A Weight Loss Maintenance Study
A study to investigate the effect of a low-ED prescription (consume ≥10 foods ≤ 1.0 kcal/g and ≤ 2 foods ≥ 3.0 kcal/g per day) versus an energy balance prescription (consume a daily energy intake at estimated energy needs for…
- Trial name
- NCT01849627
- Testing
- Low-ED, Energy Balance
- Where
- United States
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Obesity
Autophagy and Inflammasome in Obesity: Effect of Weight Loss and Potential Therapeutic Implications
The main aim of this project is to determine the implication of autophagy and inflammasome in the pathogenesis of obesity and related comorbidities, and to explore in depth the mechanisms associated with the activation of immune…
- Trial name
- NCT05071391
- Testing
- Roux-en-Y gastric bypass
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Milagros Rocha Barajas
Accuracy of Clinic-based Weight Measurements
Evaluating Expectancy Effects in Weight Loss Measurement
The purpose of this project is to examine potential bias or expectancies in individuals' measurement and recording of weight in a clinical-research setting.
- Trial name
- NCT02101658
- Testing
- clinic-based weight measurements
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Osteoarthritis, Knee, Obesity
Long-term Intervention With Weight Loss in Patients With Concomitant Obesity and Knee Osteoarthritis. The LIGHT Study
Obesity and osteoarthritis (OA) co-exist in an increasing part of the population. The two diseases intertwine in several ways. The evolution in the population shows a tendency towards deterioration of both by increasing general…
- Trial name
- LIGH T (NCT00938808)
- Testing
- day formula diet
- Where
- Denmark
- Volunteers
- 154 people
- Sponsor
- Henning Bliddal
Body Weight Decreased
Low Energy Dense, Weight Maintenance, Risk of Cardiovascular Disease
Investigators presumed that low energy density (LED) diet consumers will have lower risk of cardiovascular disease and are able to maintain their weight longer .
- Trial name
- NCT01659450
- Testing
- low energy dense, control, diet
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Underweight, Wasting
Preventing Infant Malnutrition With Early Supplementation
Background: Worldwide, more than 50 million children under 5 years of age are wasted (weight-for-length/height Z-score (WLZ) <-2) and over 150 million children under 5 are stunted (length/height-for-age Z-score (LAZ) <-2); such…
- Conditions
- Underweight, Wasting, Stunting, Breastfeeding
- Trial name
- PRIMES (NCT04704076)
- Testing
- ESVS, Exclusive breastfeeding
- Where
- 2 sites in Guinea-Bissau, Uganda
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Obesity
Lifestyle Modification and Lorcaserin for Weight Loss Maintenance
The proposed 12-month randomized controlled trial will assess the efficacy of lifestyle counseling, combined with lorcaserin (10 mg BID) or placebo, in maintaining weight loss achieved during a prior 14-week dietary run-in.
- Trial name
- NCT02388568
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Pennsylvania
Body Weight Changes
Pre Competition Weight Loss of Athletes
The objective of this observational study is to assess the long-term impact of a combined slow and rapid weight reduction strategy on the physiological performance, mental state, and sleep quality of male freestyle wrestlers.
- Trial name
- NCT06543017
- Testing
- Experimental group
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
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