Clinical trials: Weight Loss, completed
Obesity, Weight Loss
The Effect of Weight Loss on Serum Mannose-Binding Lectin(MBL) Levels
High levels of mannose-binding lectin (MBL), an activator of a part of the immune system called the complement system, have been associated with increased mortality and risk of early signs of kidney damage in patients with type 2…
- Trial name
- WLMBL (NCT00854412)
- Testing
- Weight loss
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Obesity
Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, Volunteers
The purpose of this study is to determine whether CP-866,087 is effective in the weight loss of overweight patients.
- Trial name
- NCT00479492
- Testing
- CP-866,087
- Where
- 4 sites in United States
- Volunteers
- 94 people
- Sponsor
- Pfizer
Obesity, Appetitive Behavior
Regulation of Energy Balance and Metabolism - Mechanisms Behind and Beyond Obesity and Weight Loss
The study aims to investigate homeostatic and hedonic mechanisms regulating appetite, energy balance and metabolism in obesity and the effects of three distinct obesity treatments on these regulatory mechanisms.
- Trial name
- BALANCE (NCT03550339)
- Testing
- SURG, DIET, HAES
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Overweight, Obesity
Effects of WB-EMS and Protein Supplementation on LBM Maintenance During Intended Weight Loss
The present study aimed to determine the effect of different interventions on lean body mass maintenance under weight loss conditions in overweight and obese premenopausal women.
- Conditions
- Overweight, Obesity, Abdominal Obesity
- Trial name
- NCT03746977
- Testing
- Protein, Walking, WB-EMS application
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Cholesterol Lowering
Influence of Polyglucosamine L112 on Serum Surrogate Markers of Cholesterol Absorption
Obesity is widespread and the number of overweight people has tripled from 1975 to 2016. According to the WHO (World Health Organisation), 1.9 billion adults worldwide are overweight, of which 650 million are obese.
- Trial name
- NCT05038436
- Testing
- Polyglucosamine L112
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Certmedica International GmbH
Hypogonadism, Hypogonadotropic, Obesity
Aromatase Inhibitors and Weight Loss in Severely Obese Men With Hypogonadism
The investigators have preliminary data suggesting that obese patients with hypogonadotropic hypogonadism (HHG) have minimal benefit from testosterone therapy likely because of its conversion to estradiol by the abundant…
- Trial name
- NCT03490513
- Testing
- anastrozole (1 mg/day)
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Baylor College of Medicine
Type 2 Diabetes
Diet and Exercise Intervention in Type 2 Diabetes
The purpose of this study is to determine the effect of a worksite-based intensive lifestyle therapy intervention (weight loss with exercise training) on blood sugar control in people with obesity and type 2 diabetics.
- Trial name
- LID (NCT01977560)
- Testing
- Intensive Lifestyle Intervention, Standard Care
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Washington University School of Medicine
Type 2 Diabetes, Overweight
Effects of Replacing Diet Beverages With Water on Weight Maintenance of Type 2 Diabetic Obese Women: 18 Months Follow up
the present study aimed to follow up our participants in order to consider the changes in weight and anthropometric measurements after the 12-month weight maintenance as well as the total of 18 months, consisting of the…
- Conditions
- Type 2 Diabetes, Overweight, Obese
- Trial name
- NCT03726762
- Testing
- DBs at the end of the main meal + weight control program, Water at the end of the main meal+ weight control program
- Where
- Iran
- Volunteers
- 81 people
- Sponsor
- Novindiet Clinic
Weight Loss, Mood
Effects of Lactobacillus Plantarum KABP-51 Probiotic on Body Composition, Microbiome and Mood in Healthy Overweight Adults
The objective of this study is to recruit 60 healthy moderately overweight subjects to participate in a research study investigating the effects of a specific probiotic strain (Lactobacillus plantarum KABP-51) on measures of…
- Trial name
- NCT06808061
- Testing
- Lactobacillus plantarum
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- 3 Waves Wellness
Obesity
Comparison of Popular Weight Loss Diets
This study will compare the safety and effectiveness of three popular weight loss plans. These plans will be compared with the USDA Dietary Guidelines.
- Trial name
- NCT00079573
- Testing
- Atkins diet (extremely low carbohydrate), Zone diet (low carbohydrate, high protein), Ornish diet (very low fat)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Obesity
The Energy Balance Study
Very low carbohydrate diets and high-complex carbohydrate, low-fat diets are popular weight-loss methods in the United States. The purpose of the Energy Balance Study is to explore how extreme differences in diet affect eating…
- Trial name
- EBS (NCT01029483)
- Testing
- Low carbohydrate diet, High-carbohydrate ad libitum intervention, High carbohydrate diet-energy matched intervention
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Advanced COPD (GOLD Stage 3 or 4) With Cachexia
Efficacy of Serum Bovine Immunoglobulin in Improving Nutritional Status in Advanced COPD
This study will evaluate the use of a medical food, oral serum-derived bovine immunoglobulin/protein isolate (SBI), in helping patients with advanced COPD with cachexia (a wasting syndrome) improve their nutritional status and…
- Trial name
- SBI for COPD (NCT02067377)
- Testing
- Serum bovine immunoglobulin (SBI) medical food
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Weight Loss
PENS T6 With Ambulatory Self-applied Patch vs Conventional Procedure
A prospective randomized study, including moderately obese patients will be included. Patients will be randomized in 3 groups: PENS of dermatome T6 with an ambulatory self-applied patch + 1200Kcal/day diet PENS of dermatome T6…
- Trial name
- NCT02564627
- Testing
- Self-applied patch, Conventional procedure, 1200 Kcal/day diet
- Volunteers
- 90 people
- Sponsor
- Abdel Kadar Clinic
Overweight and Obesity
The Effect of Lactobacillus Delbrueckii Subsp. Bulgaricus on Human's Weight Reduction
To evaluate the improvement in weight, body fat, and BMI after adding probiotics as a once-daily therapy for 84 days in overweight individuals.
- Trial name
- NCT06244186
- Testing
- Probiotics
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- China Medical University Hospital
Lean Body Mass, Cannabis
The Effect of Cannabidiol on Lean Body Mass in Patients Receiving Chemotherapy
An intervention study on the effect of cannabidiol on lean body mass in cancer patients receiving chemotherapy, at the department of Clinical Oncology at Zealand University Hospital, Roskilde, Denmark.
- Conditions
- Lean Body Mass, Cannabis, Cancer, Nausea
- Trial name
- NCT04585841
- Testing
- Cannabidiol
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Copenhagen
Visceral Fat, Weight Loss
The Effect of Mild Weight Loss on Circulating Metabolite Profiles
To determine whether low calorie diet (LCD)-induced weight reduction caused changes in plasma metabolites and metabolic traits from baseline.
- Trial name
- NCT03135132
- Testing
- Control group, LCD group
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Cachexia, NSCLC
Pilot Study of Safety and Tolerability of Nutrifriend Cachexia in NSCLC Cachexia
SF-C002 is a pilot study in patients with newly diagnosed NSCLC suffering from involuntary weight loss. The study is 12 weeks, double-blinded, placebo controlled and the main objective is to study the safety and tolerability of…
- Trial name
- NCT02515032
- Testing
- Nutrifriend Cachexia
- Where
- 14 sites in Croatia, Italy and 2 more
- Volunteers
- 56 people
- Sponsor
- Smartfish AS
Malnutrition
Prevention of Weight Loss in Long Term Care Veterans
Background: Numerous studies have shown that many LTC residents receive inadequate staff assistance with eating, which places them at risk for under-nutrition, dehydration and weight loss.
- Trial name
- NCT00841412
- Testing
- Immediate Intervention Group, Delayed Intervention Group
- Where
- United States
- Volunteers
- 222 people
- Sponsor
- US Department of Veterans Affairs
Obesity, Overweight
Effectiveness Between Nutritional Counseling Monthly Phone Call Versus Self Help Informative Booklet
The purpose of this study is to evaluate the most effectiveness between a personalized nutritional program with a counseling monthly phone call Versus personalized nutritional program with self help Informative Booklet in a group…
- Trial name
- NCT01602965
- Testing
- Counseling Monthly Phone Calls, Self Help Informative Booklet
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituto Ortopedico Rizzoli
Obesity, Type 2 Diabetes
Changes in Ectopic Fat Following Surgically Induced Weight Loss
This study evaluates how ectopic fat (in the pancreas, heart, liver and skeletal muscle), visceral fat, and subcutaneous fat changes following surgically induced weight loss using gastric banding.
- Trial name
- NCT00840307
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas Southwestern Medical Center
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