Clinical trials: Weight Loss, completed
Obesity, Overweight
The Peer Assisted Lifestyle Intervention
The PAL intervention uses a new software tool delivered on tablets to facilitate 5As-based weight management counseling with a peer health coach and the VA PACT healthcare team to promote goal-setting, behavior change, and weight…
- Trial name
- PAL (NCT03163264)
- Testing
- Peer Assisted Lifestyle, Enhanced Usual Care
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- VA Office of Research and Development
Obesity
Integrating Online Weight Management With Primary Care Support
The goal of this project is to adapt an evidence-based online weight management program and integrate it with population management support from primary care practices.
- Trial name
- PROPS (NCT02656693)
- Testing
- Online weight management program, Population health management support
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Brigham and Women's Hospital
Gastrointestinal Neoplasms, Bronchial Carcinoma
Effect of an Antioxidant on Cancer-Cachectic Patients Undergoing Exercise Training
The purpose of the study is to tests the hypothesis, that N-acetylcysteine (a thiol-antioxidant)improves the exercise training effect on cancer patients that experience weight loss (cachexia) as assessed by muscle mass and…
- Conditions
- Gastrointestinal Neoplasms, Bronchial Carcinoma, Hodgkin Disease, Non-Hodgkin Lymphoma
- Trial name
- NCT00196885
- Testing
- N-acetylcysteine
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Cancer Research Center
Cancer Cachexia, Head and Neck Cancer
Effect of Omega-3 Supplements on the Prevention of Cachexia in Head and Neck Cancer Treated With Radio(Chemo)Therapy
Cancer cachexia is a complex metabolic process affecting up to 80% of patients suffering from an advanced-stage cancer. Moreover, 20 to 40% of all cancer deaths are caused directly by cachexia.
- Trial name
- NUTRIOM (NCT01596933)
- Testing
- BioMega SDA®, Sunflower oil high oleic
- Where
- 2 sites in Belgium
- Volunteers
- 91 people
- Sponsor
- General Hospital Groeninge
Energy Expenditure, Appetite
Evaluation of Metabolism-Boosting Beverages
The purpose of this study is to assess the effect of Metabolism-boosting Beverages (MBB) containing green tea extract with a standardized amount of epigallocatechin gallate (EGCG) and caffeine.
- Trial name
- NCT01029236
- Testing
- Medifast Metabolism-boosting Beverages
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
Obesity
Noom Coach for Bariatric Surgery
The prevalence of overweight in America is a national public health crisis. As more people consider bariatric surgery for the treatment of severe obesity, it is imperative to identify factors influencing surgical outcomes.
- Trial name
- NCT03386006
- Testing
- Noom Coach for Bariatric Health
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Noom Inc.
Obesity, Apathy
Role of Apathy in the Effectiveness of Weight Loss Interventions
The purpose of this study is to determine whether treating apathy with methylphenidate or medical Crisis counselling will increase adherence to weight loss programs thereby increasing their effectiveness
- Trial name
- NCT00548652
- Testing
- MOVE, medical crisis councelling, methyphenidate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- VA Nebraska Western Iowa Health Care System
Obesity
Peer-enhanced Intervention to Support Teen Weight Loss
The purpose of this study is to determine whether adding a peer-based intervention based on an outward bound model is more effective than a standard behavioral weight intervention for helping adolescents lose weight.
- Trial name
- NCT00285558
- Testing
- CBT with peer-enhanced activities, CBT with supervised aerobic exercise
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Enhanced Internet Behavior Therapy for Treating Obesity
The purpose of this study is to compare two Internet-based behavioral weight loss programs.
- Trial name
- NCT00212238
- Testing
- internet behavioral weight loss program
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Diabetes
Time Restricted Feeding (4-hour Versus 6-hour) for Weight Loss in Obese Adults
The aims of this proposal are to compare the effects of 4-h versus 6-h time restricted feeding (TRF) on body weight and metabolic disease risk factors in adults with obesity.
- Trial name
- NCT03867773
- Testing
- Time restricted feeding
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Heart Failure, Malnutrition
Food As Medicine for Heart Failure
Malnutrition and unintentional weight loss are highly prevalent among patients with heart failure (HF), with approximately 50% of patients with heart failure meeting malnutrition criteria.
- Trial name
- FAM-HF (NCT04847973)
- Testing
- Medically-Tailored Meals (MTMs), Protein supplementation shakes
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Tufts Medical Center
Overweight, Obesity
Internet Assisted Obesity Treatment
High quality behavioral weight loss programs are not widely accessible. The Internet offers one way to deliver health behavior programs to a wider audience.
- Trial name
- iReach (NCT00265954)
- Testing
- internet, in-person and internet+in-person
- Where
- 2 sites in United States
- Volunteers
- 481 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Diet Therapy
High Pasta vs. Low Pasta Diet in the Treatment of Obesity
To the best of our knowledge, the effect of pasta consumption within a hypocaloric Mediterranean diet has only been scarcely explored yet.
- Trial name
- NCT03341650
- Testing
- High Pasta, Low Pasta
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Parma
Metabolic Syndrome
A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults
The present study is designed to examine the effect of changes in body weight and related parameters associated with a commercially-available, low-carbohydrate diet plan.
- Trial name
- NCT02774668
- Testing
- "Grab-and-Go" meal plan, "Jump-Start" meal plan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Weight Loss
Clinical Study to Investigate the Effects of a Food Supplement Santa Herba Extract on Weight Loss in Overweight Women
Aim of the study is to investigate the effect of a 12-week supplementation of Santa Herba Extract on body weight in overweight and obese subjects.
- Trial name
- NCT03853603
- Testing
- Santa herba
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mibelle AG
Asthma, Overweight
Weight-reduction Intervention in Asthmatic Children With Overweight/Obesity
The purpose of this study is to determine the efficacy of a multifactorial intervention with weight reduction, behavioural therapy, and physical exercise on the severity and control of asthma in obese children.
- Conditions
- Asthma, Overweight, Obesity
- Trial name
- NCT00998413
- Testing
- Multifaceted intervention
- Where
- 2 sites in Netherlands
- Volunteers
- 87 people
- Sponsor
- Maastricht University Medical Center
Overweight and Obesity
Novel Executive Function Training for Obesity
Currently, the best behavioral treatments for obesity only work for 50% of adults, and of those who initially succeed, most do not maintain their weight loss.
- Trial name
- NEXT (NCT03724396)
- Testing
- Behavioral Weight Loss - BWL, Novel Executive Function Training - NEXT
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Obesity
A Multicenter Study for Pre-Surgical Weight Loss
The purpose of the study is to evaluate the safety and initial efficacy of the EndoBarrier device compared to a diet control in patients who require weight loss prior to their Bariatric surgery.
- Trial name
- NCT00830440
- Testing
- EndoBarrier Device, Diet & Lifestyle Counseling
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Morphic Medical Inc.
Weight Loss
Facebook and Friends: Developing an Effective Online Social Network for Weight Loss
In a pilot randomized trial of 160 obese participants, investigators will test the feasibility of a behavioral weight loss program delivered entirely via Facebook. We will recruit in 2 separate waves of 80 participants each.
- Trial name
- NCT02656680
- Testing
- Continuous Enrollment, Closed Enrollment
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Ulcer Disease After Gastric Bypass, Marginal Ulcer
Perforated Marginal Ulcer After Gastric Bypass
A common late complication after gastric bypass surgery is marginal ulceration that is defined as ulcers at the margins of the gastrojejunostomy, mostly on the jejunal side.
- Conditions
- Ulcer Disease After Gastric Bypass, Marginal Ulcer, Perforated Marginal Ulcer, Acutely Perforated Marginal Ulcer
- Trial name
- PerforatedMU (NCT01041196)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
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