Clinical trials: Weight Loss, completed
Obesity
Metabolic Flexibility and Metabolic Heath in Human Obesity
This interventional study explores the relationship between improvements in metabolic health following weight loss and changes in whole-body fat mass and its distribution.
- Trial name
- PROB (NCT07355933)
- Testing
- Body Weight Loss
- Where
- Chile
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Jose Galgani
Obesity
Proof-of-Concept Study of an Integrated Mobile and Social Network Weight Loss Intervention
The purpose of this 6 week single-arm pilot is to evaluate the feasibility of the Habit app plus Facebook group intervention in 20 adults with obesity.
- Trial name
- BHT-OWL (NCT05295849)
- Testing
- Building Habits Together Online Weight Loss 6-Week Usability Trial
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Connecticut
Body Weight, Body Composition
Use of Conjugated Linoleic Acid as a Nutraceutical for Weight Loss in Humans
The purpose of the study is to examine how a naturally occurring fat found in meats, such as beef and lamb and milk, called conjugated linoleic acid (CLA), will affect your body weight and body fat content, blood fat levels, as…
- Conditions
- Body Weight, Body Composition, Hyperlipidemia, Inflammation
- Trial name
- CLA (NCT01047280)
- Testing
- Clarinol G-80 ® treatment, Safflower oil, G-c9, t11
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Appetitive Behavior
Scot Sweet Study (Interaction of a Non-nutritive Sweetener With a High-fibre Weight Loss Diet)
The investigators present a weight loss diet intervention study, to be conducted as a within-subject design, with all food and beverages provided, to assess interaction of non-nutritive sweetener (sucralose) with a high-fibre…
- Trial name
- SSS (NCT05892003)
- Testing
- Phase 1 Control, Phase 2 High Fibre Weight Loss, Phase 3 High Fibre and Non-Nutritive Sweetener Weight Loss
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Breast Cancer, Weight Loss
Lifestyle, Exercise and Nutrition Study 2 (LEAN 2)
The specific aims of this study are to determine the efficacy and cost-effectiveness of a weight loss program compared with usual care (control) treatment on 6-month changes in body weight, body fat, serum hormones, and breast…
- Trial name
- LEAN 2 (NCT02110641)
- Testing
- Weight Loss Counseling
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Weight Loss
Effects of Dietary Pork and Egg on Appetite, Meal-patterning, and Weight Loss in Men
The purpose of this study is to identify how adult men respond to a weight loss diet that includes pork and eggs and increasing the number of meals consumed throughout the day.
- Trial name
- NCT00812162
- Testing
- Energy Restriction
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Purdue University
Hypothalamic Obesity
Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity
The proposed multicenter study will test the effect of glucagon-like peptide (GLP)-1 agonist exenatide once weekly extended-release (ExQW, Bydureon®) on clinical outcomes and metabolic parameters in a double-blind…
- Trial name
- ECHO (NCT02664441)
- Testing
- Exenatide
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Seattle Children's Hospital
Obesity
A Facebook-based Weight Loss Programme for Obese Adults in Hong Kong
The purpose of this study is to determine the feasibility and efficacy of a 6-month weight loss intervention program for obese working adults through a popular social networking site - Facebook.
- Trial name
- NCT02616237
- Testing
- Lifestyle Intervention
- Where
- Hong Kong
- Volunteers
- 59 people
- Sponsor
- The Hong Kong Polytechnic University
Obesity
The ACE Follow-up Study
The Articulating Circular Endoscopic (ACE) Stapler is an investigational system using endoscopic guidance to trans-orally place plications in the stomach in obese subjects to reduce volume and expansion of the fundus and greater…
- Trial name
- NCT01429194
- Testing
- ACE Stapler
- Where
- 6 sites in Argentina, Canada and 2 more
- Volunteers
- 69 people
- Sponsor
- Boston Scientific Corporation
HIV Infections, Insulin Resistance
Diet, Exercise and/or Rosiglitazone for HIV-Associated Insulin Resistance
The purpose of this study is to determine if, in men and women with excess abdominal fat and insulin resistance, people with HIV infection respond differently than people without HIV to interventions that typically improve body…
- Conditions
- HIV Infections, Insulin Resistance, Obesity
- Trial name
- NCT00264251
- Testing
- Weight loss through diet and exercise, Rosiglitazone insulin sensitizing agent
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Weight Loss, NASH
Phase 1 Study to Evaluate the Safety and Tolerability of VK2735
This is a Phase 1, randomized, double-blind, placebo-controlled single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of VK2735 in healthy adults and…
- Trial name
- NCT05203237
- Testing
- VK2735, VK2735 Drug
- Where
- Australia
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Viking Therapeutics, Inc.
Insulin Resistance, Metabolic Syndrome
Gene Expression in Obesity and Insulin Resistance
Lifestyle and genetic factors interact in the development of obesity and the metabolic syndrome. The molecular mechanisms underlying the beneficial dietary modifications are, however, unclear.
- Trial name
- Genobin (NCT00621205)
- Testing
- Weight reduction, Resistance training, Aerobic exercise training, Control
- Where
- Finland
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Marjukka Kolehmainen
Prostate Carcinoma
Weight Loss Interventions to Reduce Cancer Progression in Prostate Cancer Patients Under Active Surveillance
This clinical trial examines weight loss interventions in reducing cancer progression in prostate cancer patients under active surveillance.
- Trial name
- NCT05764330
- Testing
- Biospecimen Collection, Dietary Intervention, Fasting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roswell Park Cancer Institute
Cancer
E-MOSAIC Electronic Tool to Monitor Symptoms
RATIONALE: A hand held electronic tool used to monitor symptoms and assess quality of life may improve communication between patients and their doctors and improve the ability to plan treatment for patients with advanced cancer…
- Trial name
- NCT00477919
- Where
- 7 sites in Switzerland
- Volunteers
- 264 people
- Sponsor
- Swiss Cancer Institute
Obesity
Nutrigenomics And Children Obesity: A Moderate Weight Loss Intervention Study
The consumption of diets enriched in proteins (legumes and fish) or antioxidant (fruits and vegetables) could have beneficial effects beyond those of the caloric restriction on biomarkers of the inflammatory and oxidative status.
- Trial name
- NUGENOI (NCT01329367)
- Testing
- Control group, Protein group, Antioxidant group
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Weight Loss, Pediatric Obesity
iAmHealthy Parents First: A Televideo Parent and Child Obesity Program for Rural Families
The purpose of this study is to assess whether providing a parent-only group program before providing a parent and child group program works better than the parent and child group program alone.
- Trial name
- NCT05612971
- Testing
- iAmHealthy Parents First, iAmHealthy
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Kansas Medical Center
Chronic Kidney Disease, Bariatric Surgery Candidate
Weight Loss in Obese Kidney Disease Patients After Bariatric Surgery
This study is designed as a prospective, single-center, longitudinal and analytical study on the effect of bariatric surgery in obese patients with chronic kidney disease (CKD).
- Trial name
- NCT02644928
- Where
- Spain
- Volunteers
- 12 people
- Sponsor
- Enrique Morales Ruiz, MD
Hypogonadism, Obesity
Testosterone Replacement Therapy and Liraglutide Effects on Weight Loss in Hypogonadism.
The purpose of this study was to compare the effects of liraglutide and testosterone replacement therapy on features of hypogonadism and weight loss in obese men with persistent features of hypogonadism after unsuccessful…
- Trial name
- NCT03619330
- Testing
- liraglutide, Testosterone
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Weight Loss
Lorcaserin: Real World Experience in an Insurance-Based Weight Management Clinic
This is a retrospective, descriptive study that involves de-identified data consisting of weight changes, pertinent vital signs and laboratory values influenced by body weight, and healthcare utilization of patients prescribed…
- Conditions
- Obesity, Weight Loss, Overweight
- Trial name
- NCT03552107
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Scripps Whittier Diabetes Institute
Breast Cancer
Weight Reduction Intervention for Breast Cancer Survivors
Overweight or obesity is an established negative prognostic factor in both premenopausal and postmenopausal breast cancer. Several mechanisms have been proposed to explain the adverse effect of excess body fat on prognosis…
- Trial name
- SHAPE (NCT00774371)
- Testing
- Cognitive behavioral therapy CBT) for weight loss
- Where
- United States
- Volunteers
- 253 people
- Sponsor
- University of California, San Diego
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