Clinical trials: Weight Loss, completed
Generalized Lipodystrophy
A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)
This study is researching an experimental drug called mibavademab. The study is focused on participants with GLD who have been on metreleptin treatment for at least 6 months with no change in dose for the last 3 months.
- Trial name
- NCT06548100
- Testing
- mibavademab
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Regeneron Pharmaceuticals
Overweight and Obesity
Trial to Examine the Effect of Natural Anti- Obesity Agent (Phaseolus Vulgaris) Among Women of Lahore
This double-blind randomized placebo-controlled trial will test the hypothesis that administration of Phaseolus Vulgaris supplementation to women in Lahore, Pakistan, who are overweight will induce the weight loss (Primary…
- Trial name
- PVE-AO (NCT05451927)
- Testing
- Phaseolus Vulgaris
- Where
- 2 sites in Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hafiza Aisha Sadiqa
Weight Loss
Lifestyle Modification for Weight Reduction With Peer Support Among Adults in an Urban Slum of Karachi, Pakistan
The feasibility study was conducted using a mixed-methods single group, pre and post-test design (Quasi experiment) approach. The investigator assessed if a weight reduction program using WhatsApp and peer support would work well…
- Trial name
- NCT05928338
- Testing
- Peer-supported, WhatsApp-assisted lifestyle modification intervention
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Overweight and Obesity
Extension Study of Gelesis100 on Body Weight
This study is designed to assess the effect of Gelesis100 on body weight after an additional exposure of 24 weeks in subjects who completed the 24-week treatment period, and had at least 3% weight loss, in the Gelesis Loss Of…
- Trial name
- GLOW-EX (NCT03021291)
- Testing
- Gelesis100 (2.25 g)
- Where
- 16 sites in United States, Czechia and 3 more
- Volunteers
- 36 people
- Sponsor
- Gelesis, Inc.
Obesity, Weight Gain
Effects of Monosodium Glutamate on Energy Balance and Eating Behavior
This study will test whether regular consumption of Monosodium Glutamate (MSG) immediately prior to each of the three major meals (breakfast, lunch, dinner) inhibits body weight and fat regain following a period of moderate, yet…
- Conditions
- Obesity, Weight Gain, Food Preferences
- Trial name
- NCT01410838
- Testing
- Broth
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- USDA, Western Human Nutrition Research Center
Stigmatization, Obesity
Psychological Intervention to Reduce Weight Bias Internalization
This is a randomized controlled trial to test the effects on WBI of a novel psychological intervention combined with standard behavioral weight loss (BWL) treatment, as compared to BWL alone.
- Conditions
- Stigmatization, Obesity, Weight Loss
- Trial name
- NCT03572218
- Testing
- BWL, BIAS
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Pennsylvania
Obesity, Weight Loss
A Study of a Values-Based Intervention to Promote Weight Loss
More than 160 million American adults are overweight or obese. Existing weight loss interventions from self-help to gold standard behavioral treatments, while often effective, do not sufficiently maintain motivation to adhere to…
- Trial name
- NCT03991676
- Testing
- Values-Based Behavioral Treatment
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Drexel University
Obesity or Overweight
A Weight Loss Study Evaluating Subcutaneous Treatment With AZD9550 and AZD6234 in Combination Against Placebo or Each of the Drugs Alone
The purpose of this study is to determine whether treatment with AZD9550 when given in combination with AZD6234 as once weekly subcutaneous (SC) injections is superior to placebo or either agent administered as monotherapy for…
- Trial name
- ASCEND (NCT06862791)
- Testing
- AZD9550, AZD6234
- Where
- 53 sites in United States, Australia and 3 more
- Volunteers
- 377 people
- Sponsor
- AstraZeneca
Metabolic Syndrome, Overweight or Obesity
Impact of Time-Restricted Eating on Metabolic Homeostasis, Inflammation and Oxidative Stress in Metabolic Syndrome
The main purpose of the clinical trial is to determine the health impact of a dietary intervention known as time-restricted eating (TRE) in patients with metabolic syndrome (defined as the presence of elevated fasting plasma…
- Conditions
- Metabolic Syndrome, Overweight or Obesity, PreDiabetes, Weight Loss
- Trial name
- TREMNIOS (NCT04328233)
- Testing
- Time-Restricted Eating
- Where
- Poland
- Volunteers
- 27 people
- Sponsor
- Nicolaus Copernicus University
Obesity
Transoral Gastric Volume Reduction as an Intervention for Weight Management
The purpose of this study is to evaluate the safety, technical feasibility, and initial effectiveness (i.e., weight loss primarily measured as percent excess weight loss) of TGVR performed using the Bard RESTORe Suturing System
- Trial name
- TRIM (NCT00679848)
- Testing
- RS2 (RESTORe Suturing System)
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- C. R. Bard
Obesity
Pilot Study Testing Professional, Peer, and Mentor Health Coaches for Weight Loss
Participants will be randomly assigned to 1 of 3 types of health coaches, Peers, Mentors, or Professionals. The aim of this study is to examine the feasibility and preliminary efficacy of health coaching for weight loss.
- Trial name
- NCT01211574
- Testing
- peer coach, mentor, Professional
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
PCOS, Obesity
Polycystic Ovary Syndrome and Liraglutide as Add-on Therapy on Metformin
The purpose of this study was to determine whether combined treatment with liraglutide and metformin is more effective than liraglutide or metformin as monotherapy in the treatment of obese women with polycystic ovary syndrome…
- Trial name
- NCT01911468
- Testing
- metformin, liraglutide, metformin and liraglutide
- Where
- Slovenia
- Volunteers
- 36 people
- Sponsor
- University Medical Centre Ljubljana
Obesity, Weight Loss
Healthy Eating Patterns During a Lifestyle Intervention
The purpose of this study is to address the gap in knowledge regarding the relationship between eating frequency and weight loss.
- Trial name
- HEP (NCT01682317)
- Testing
- Eating Frequency
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Breast Cancer Female
Feasibility of High Levels of Energy Expenditure From Physical Activity for Breast Cancer Survivors
The purpose of the study is to demonstrate that breast cancer survivors who need to lose weight are able to follow a weight loss program which combines modest calorie restriction with a graduated activity program..
- Trial name
- NCT02963740
- Testing
- Supervised Exercise, Home-based Exercise, Group Phone Calls
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Kansas Medical Center
Obesity and Overweight, the Study Will Focus on Weight Reduction Through Lifestyle Changes Aided by Insights From Continuous Glucose Monitoring
The Impact of CGM on Weight Reduction
The goal of this randomized control study is to learn if continuous glucose monitoring (CGM) can aid in weight loss in overweight/obese women with no other chronic condition.
- Trial name
- NCT07026903
- Testing
- resistance exercise and calorie restrictive diet
- Where
- Croatia
- Volunteers
- 35 people
- Sponsor
- University of Zagreb
Diabetes Mellitus Risk, Obesity
Novel Intervention Linking Public Housing With Primary Care to Prevent Diabetes
(Sisters Health And Primary CarE Uniting and Preventing Diabetes; aka SHAPE UP) will consist of: 1) Neighborhood DPP Intervention: group DPP sessions and individual coaching; 2) Preventive Care Coordination to FQHC: referral…
- Conditions
- Diabetes Mellitus Risk, Obesity, Cardiovascular Risk Factor
- Trial name
- SHAPE-Up (NCT03526237)
- Testing
- 24 week community based DPP Group Lifestyle Balance Program, Wait-List Control community based DPP Group Lifestyle Balance Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obese, Weight Loss
Effects of Adding L-BAIBA or L-BAIBA + Grains of Paradise to Exercising Adult Overweight and Obese Men and Women
The goal of this intervention study is to examine changes in body composition, weight loss, and cardio-metabolic risk factors after adding supplementation of L-Beta aminoisobutyric acid (L-BAIBA) and Grains of Paradise to…
- Conditions
- Obese, Weight Loss, Body Weight, Cardiometabolic Syndrome
- Trial name
- GOP (NCT05775003)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Infertility, Overweight and Obesity
Healthy Parents - Healthy Children. Weight Loss Before Fertility Treatment
The detrimental effect of overweight and obesity on fecundity has been well documented. The investigators wish to investigate the intervention program for weight loss before fertility treatment.
- Conditions
- Infertility, Overweight and Obesity, Weight Loss, Vaginal Flora Imbalance
- Trial name
- NCT04721938
- Testing
- Systematic weight loss intervention
- Where
- Denmark
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Arthroplasties, Replacement, Weight Loss
Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App
The purpose of this trial is to assess the impact of a 12-week remote dietitian supervised dietary and physical activity weight loss intervention and mobile app for patients with morbid obesity prior to undergoing total joint…
- Conditions
- Arthroplasties, Replacement, Weight Loss, Nutrition
- Trial name
- NCT04330391
- Testing
- Remote dietitian supervised weight loss intervention and mobile app
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Diabetes Mellitus, Type 2
Digital Diabetes Remission Trial
This is a multicentre, open-label Randomised Controlled Trial run in the United Kingdom. The main aims are to assess whether the Habitual Remission Programme (digital therapeutics + 12-week 800kcal/day low-energy diet, delivered…
- Trial name
- DIGEST (NCT05647226)
- Testing
- Digital therapeutic and intensive lifestyle programme, Standard of care
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Habitual Health Ltd
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.