Clinical trials: Weight Loss, completed
Morbid Obesity
Laparoscopic Internal Gastric Banding, New Simple and Costless Weight Loss Procedure
The purpose of this study is to study the effectiveness of laparoscopic internal gastric banding as a treatment for morbid obesity in comparison to laparoscopic sleeve gastrectomy
- Trial name
- LIGB (NCT02878525)
- Testing
- Laparoscopic internal gastric banding, laparoscopic sleeve gastrectomy
- Where
- 2 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Minia University
Weight Loss
Testing Strategies to Encourage Weight Loss in an Employer Setting
This is a 3-arm pilot randomized controlled trial to evaluate the effectiveness of two novel ways of structuring financial incentives to motivate and sustain long-term weight loss.
- Trial name
- NCT01208350
- Testing
- No intervention, Group-based payout, Individual payout
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Acute Malnutrition in Childhood, Wasting
Treatment of Acute Malnutrition in Outpatient Care Services in Venezuela: a Prospective Cohort Research
The goal of this observational study is to compare the effectiveness, safety, and efficiency of the simplified protocol, which includes the following three modifications: a) use of a single treatment product (RUTF), b) reduced…
- Conditions
- Acute Malnutrition in Childhood, Wasting, Child Malnutrition
- Trial name
- NCT06287827
- Testing
- Simplified protocol, Standard protocol
- Where
- 4 sites in Venezuela
- Volunteers
- 299 people
- Sponsor
- UNICEF - Venezuela
HIV, Pregnancy
Maternal Determinants of HIV-exposed and HIV-unexposed Fetal Growth, Birth Outcomes and Early Infant Growth
The purpose of this study is to understand how differences in the nutritional status and concentration of hormones and cytokines associated with cachexia in HIV+ and HIV- pregnant women living in a semi-rural and rural region of…
- Conditions
- HIV, Pregnancy, Malnutrition, Cachexia
- Trial name
- NCT01647841
- Where
- Tanzania
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- Cornell University
Obesity
A Study of the TransPyloric Shuttle™ (TPS™) for Weight Reduction in Obese Subjects
The purpose of this study is to assess the feasibility of the TransPyloric Shuttle™ (TPS™) when used to treat obesity.
- Trial name
- NCT01386905
- Testing
- BAROnova™ TransPyloric Shuttle™ (TPS™)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- BaroNova, Inc.
Obesity
Impact of Weight Loss on Physical Function
We are proposing a trial to directly compare a high intensity weight loss protocol to a moderate intensity weight loss protocol to determine which leads to greater improvements in physical function in severely obese older adults.
- Trial name
- OPTIFAST (NCT02079051)
- Testing
- Moderate intensity weight loss, High intensity medical weight loss
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Functional Dyspepsia
Mirtazapine Versus Placebo in Functional Dyspepsia
Double-blind randomized controlled trials of 8 weeks mirtazapine 15 mg daily or placebo, followed by 8 weeks of open-label mirtazapine 15 mg daily
- Trial name
- NCT01240096
- Testing
- Mirtazapine
- Where
- Belgium
- Volunteers
- 35 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Obesity, Hypertension
Feasibility of Integrating Indirect Calorimetry (IC) Technology in Primary Care
The purpose of this study is to evaluate the feasibility of using indirect calorimetry (IC) within a comprehensive weight reduction program.
- Trial name
- NCT00750022
- Testing
- Individualized IC treatment, Usual Care
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Chronic Care Innovations, Inc.
Obesity
Evaluating the Efficacy of AI-Guided (GenAIS TM) vs. Standard Physician-Guided Dietary Supplement Prescriptions for Weight Loss in Obese Patients
Obesity, a chronic disease characterized by excessive fat accumulation, significantly impacts health. Genetic factors influence the development of obesity by affecting behavioral, dietary habits, and metabolic processes.
- Trial name
- NCT06458296
- Testing
- Control Group, AI-Guided Group
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- S.LAB (SOLOWAYS)
Obesity
Support and Tracking to Achieve Results (Project STAR)
The investigators propose to conduct a randomized controlled trial assessing the impact of phone-based extended care delivered on an ADAPTIVE (when participants are at "high risk" for weight regain as assessed by a predictive…
- Trial name
- NCT04116853
- Testing
- ADAPTIVE Extended-Care Program, STATIC Extended-Care Program
- Where
- United States
- Volunteers
- 255 people
- Sponsor
- University of Florida
Overweight, Obesity
Healthy Families Healthy Forces Study
U.S. Army Medical Research \& Materiel Command Telemedicine and Advanced Technology Research Center (TATRC) is sponsoring the HF2 (Healthy Families, Healthy Forces) Study.
- Trial name
- HF2 (NCT02348853)
- Testing
- Healthy Weight for Living (HWL), Current Best Practice (CBP)
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- Tufts University
Obesity
Tangji Gastric Bypass Stent Study for Obesity
The Gastric Bypass Stent System is intended to be used in weight loss treatment for obesity in patients with a BMI ≥ 30 kg/m2. In this clinical investigation the Sponsor seeks to demonstrate the safety and performance of the…
- Trial name
- NCT05938231
- Testing
- Gastric Bypass Stent System, Dietary Intervention
- Where
- 7 sites in China
- Volunteers
- 99 people
- Sponsor
- Hangzhou Tangji Medical Technology Co., Ltd.
Type 2 Diabetes Mellitus
Dietary Fatty Acids As Complementary Therapy in Type 2 Diabetes Mellitus
The purpose of the study is to see how a dietary oil called conjugated linoleic acid, or CLA, might be useful in combination with diabetes medication. Some studies show that CLA can modestly reduce body weight and body fat.
- Trial name
- FACT (NCT00607945)
- Testing
- Rosiglitazone (Avandia) OR other diabetes medication currently prescribed to participant, conjugated linoleic acid (CLA)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Ohio State University
Sarcopenic Obesity, Bariatric Surgery Candidate
Effect of Protein Supplementation and a Structured Exercise Program on Muscle in Women After Bariatric Surgery.
Obesity is considered a chronic disease that increases the risk of developing diseases that reduce life expectancy. The treatment of obesity is complex.
- Conditions
- Sarcopenic Obesity, Bariatric Surgery Candidate, Nutritional Deficiency, Protein Intolerance
- Trial name
- SarcoFit (NCT04771377)
- Testing
- Protein Supplementation
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Clinic of Barcelona
Advanced Heart Failure, Cardiac Cachexia
Cardiac Cachexia in Advanced Heart Failure
Heart failure is a condition in which the heart stops pumping effectively, causing symptoms such as breathlessness or leg swelling. It affects around 900,000 people in the United Kingdom.
- Conditions
- Advanced Heart Failure, Cardiac Cachexia, Weight Loss
- Trial name
- CACH-IT-AHF (NCT06259045)
- Where
- United Kingdom
- Volunteers
- 261 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
PreDiabetes, Obesity
Development of an Adaptive Treatment for Weight Loss in People With Prediabetes
This 16-week study will use an experimental approach called the Sequential Multiple Assignment Randomized Trial to help determine which combination and sequence of weight loss program features are most effective in people who are…
- Trial name
- NCT04745572
- Testing
- High Carbohydrate Diet, Reduced Carbohydrate Diet
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Breast Cancer, Overweight
Reducing Breast Cancer Recurrence With Weight Loss
The purpose of the ENERGY trial is to explore whether two different programs that are focused on weight management, through increased exercise and a healthy diet, are feasible, and have an impact on body weight, quality of life…
- Conditions
- Breast Cancer, Overweight, Obesity
- Trial name
- ENERGY (NCT01112839)
- Testing
- Less Intensive, Intensive Group
- Where
- 4 sites in United States
- Volunteers
- 692 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Men, Life Style
Dietary Effects on Weight Loss and Lipid Profile in Sedentary Men
Negative-calorie diet is among the popular dieting guides for weight loss; however, there is still little knowledge about this method.
- Conditions
- Men, Life Style, Lipid Metabolism Disorders, Obesity
- Trial name
- NCT03082794
- Testing
- NCD, LCD
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- P.L.Shupik National Medical Academy of Post-Graduate Education
Overweight, Obesity
The Healthy Weight for Life Program
This study is a randomized controlled pilot of a work site weight control intervention. The purpose of the pilot is to obtain preliminary data for future NIH submissions.
- Conditions
- Overweight, Obesity, Compliance Behavior
- Trial name
- HWL (NCT01470222)
- Testing
- Weight loss intervention
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Tufts University
Insulin Resistance, Hypertriglyceridemia
Comparing Tricor, Avandia, or Weight Loss to Lower Cardiovascular Risk Factors in People With High Triglycerides.
Approximately 1/4 of the US population has insulin resistance and the associated risk factors such as elevated lipid levels -triglycerides (type of fat from what we eat and what the liver produces and low HDL cholesterol which is…
- Trial name
- NCT00186537
- Testing
- Rosiglitazone, Fenofibrate, Weight Loss
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Stanford University
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