Clinical trials: Weight Loss, completed
Malnutrition, Diarrhoea
Reformulated F75 Milk to Treat Severe Acute Malnutrition
Inpatient treatment for complicated severe acute malnutrition (SAM) continues to have a high mortality in Africa. This is partly because children are commonly brought for admission because they are seriously ill, rather than…
- Conditions
- Malnutrition, Diarrhoea, Metabolic Disturbance
- Trial name
- F75 (NCT02246296)
- Testing
- Standard F75 Milk, Modified F75 Milk
- Where
- 3 sites in Kenya, Malawi
- Volunteers
- 842 people
- Sponsor
- University of Oxford
Aging, Cardiovascular Disease
CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet improves biomarkers of aging and prevents some age-related chronic diseases such as cancer, diabetes, and…
- Conditions
- Aging, Cardiovascular Disease, Diabetes Mellitus
- Trial name
- NCT00099151
- Testing
- Caloric Restriction (CR), Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Potential Abnormality of Glucose Tolerance, Appetite; Lack or Loss, Nonorganic Origin
Short-term Effects of a Carob Snack on Postprandial Glycemic Responses and Energy Intake and Satiety
This study investigated any potential associations between two preloads offered as snacks and postprandial glycemic response, subjective and objective appetite and energy intake in healthy, normal-weight adults.
- Trial name
- NCT02935829
- Testing
- Glucose as reference food, White bread as reference food, Carob snack as test food
- Where
- Greece
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Obesity
Recruiting and Retaining Young Adults in Behavioral Weight Loss Treatment
A randomized pilot study will be conducted, the goal of which is to determine which format represents the most viable approach to behavioral weight loss treatment with 18-25 year olds.
- Trial name
- SPARKRVA (NCT01889082)
- Testing
- Behavioral Weight Loss Intervention for Young Adults
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Virginia Commonwealth University
Obesity, Weight Loss
Longitudinal Effects of a Commercial Digital Weight Management Program on Weight Loss
This randomized controlled trial (RCT) will test how well a fully remote weight management program (Noom Weight) helps adults with overweight or obesity (BMI 25-45) achieve weight loss in both the short-term (16 weeks) and the…
- Trial name
- NCT06666842
- Testing
- Noom Weight, Educational Control
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Noom Inc.
Obesity
Effect of GLP-1 Receptor Agonism After Sleeve Gastrectomy
Observational studies suggest that bariatric surgery is the most effective intervention for weight loss. Comparative effectiveness of Roux-en-Y Gastric Bypass (RYGB) and Sleeve Gastrectomy (SG) demonstrate that RYGB is…
- Trial name
- NCT03115424
- Testing
- Saxenda, RYGB
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Schizophrenia
Pilot Trial of Naltrexone for Obesity in Women With Schizophrenia
The purpose of this clinical trial is to find out how effective low dose oral naltrexone is on reducing body weight when compared to placebo in women with schizophrenia and schizoaffective disorder.
- Conditions
- Obesity, Schizophrenia, Schizoaffective Disorder
- Trial name
- NCT00793780
- Testing
- Naltrexone 25mg
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Yale University
Weight Loss
VK2735 for Weight Management Phase 2
This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of VK2735 in adults who…
- Trial name
- VENTURE (NCT06068946)
- Testing
- VK2735
- Where
- 20 sites in United States
- Volunteers
- 176 people
- Sponsor
- Viking Therapeutics, Inc.
Fertility Issues
Impact of Bariatric Surgery on Women Fertility
Obesity is a multifactorial risk factor for subfertility, in relation to chronic hormonal change induced by adipose tissue. This prospective cohort study aims to evaluate the impact of bariatric surgery induced weight loss on…
- Trial name
- NCT05457413
- Testing
- Sleeve gastrectomy
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Psoriasis
Post-Marketing Surveillance Study of OTEZLA
To evaluate the safety and efficacy of OTEZLA in actual clinical settings of use in patients with Psoriasis vulgaris that is with an inadequate response to topical therapies and Psoriasis arthropathica 1.
- Trial name
- NCT03284879
- Where
- Japan
- Volunteers
- 1,086 people
- Sponsor
- Amgen
Weight Loss
The Safety and Efficacy of a Bone Broth Diet on Weight Loss in Obese Adults
The primary objective of this study is to investigate the safety and efficacy of a bone broth diet on weight loss in obese adults.
- Trial name
- NCT05740670
- Testing
- Dr. Kellyann's Bone Broth
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Veyl Ventures LLC
Dysphagia, Dysplasia
Esophageal Cytology With FISH in Detecting Esophageal Cancer
This clinical trial studies whether esophageal cytology plus fluorescence in situ hybridization (FISH) is equal to or better than esophago-gastro-duodenoscopy (EGD) or upper endoscopy for the early detection of esophageal cancer.
- Conditions
- Dysphagia, Dysplasia, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma
- Trial name
- NCT02100189
- Testing
- Cytology Specimen Collection Procedure, Esophagogastroduodenoscopy, Laboratory Biomarker Analysis
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Obesity, Obesity; Drug
Latino Semaglutide Study
The purpose of this study to understand better how this anti-obesity medication works to assist individuals to lose weight and maintain weight loss.
- Conditions
- Obesity, Obesity; Drug, Overweight or Obesity, Weight Loss
- Trial name
- LSS (NCT05087342)
- Testing
- Semaglutide 2.4mg
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Loma Linda University
Cancer, Cancer Cachexia
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
The purpose of this study is to evaluate the safety and effectiveness of fish oil supplements in maintaining weight in people with disease-related weight loss and/or cachexia.
- Conditions
- Cancer, Cancer Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00094562
- Testing
- Fish oil supplement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Overweight, Obesity
LIVE SMART: Smartphone Intervention for Weight Control
The purpose of this study is to compare three methods of delivering behavioral weight loss treatment.Participants are randomly assigned to one of three 18-month weight loss treatments (group, individual, or smartphone treatment).
- Trial name
- NCT01724632
- Testing
- Lifestyle Counseling
- Where
- United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Body Image, Self Esteem
The Effectiveness on an Application-Based Lifestyle Change Program on Health in Women
The purpose of this study will be to examine the effectiveness of an application-based lifestyle change program on body composition, body shape, body, image, and self-esteem in females following a 6-week period.
- Conditions
- Body Image, Self Esteem, Weight Loss, Health Behavior
- Trial name
- NCT05813548
- Testing
- FASTer Way Intervention, Control Group Intervention
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Obesity and Overweight, HIV
Effects of Tirzepatide on Weight Loss and Chronic Inflammation in People With HIV
This is a prospective cohort study of 12 overweight (with one or more weight-related condition) or obese adults with well controlled HIV-1 on antiretroviral therapy (ART).
- Conditions
- Obesity and Overweight, HIV, Chronic Inflammation
- Trial name
- NCT06935838
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Hawaii
Overweight and Obesity
Weight Watchers and Families
Research suggests that when one spouse loses weight, the other spouse does too. This study will examine whether a ripple effect is observed in untreated spouses and children of individuals participating in a nationally available…
- Trial name
- NCT03042208
- Testing
- Self guided handout, Weight Watchers
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Type 2 Diabetes, Overweight
Effects of Replacing Diet Beverages With Water on Weight Loss and Plasma Glucose Control in Type 2 Diabetes
The purpose of the present study is to evaluate the effect of replacing diet beverages with water on weight loss and biochemical indicators for insulin sensitivity and cardiometabolic risk factors of diabetic obese and overweight…
- Conditions
- Type 2 Diabetes, Overweight, Obese
- Trial name
- NCT02412774
- Testing
- DBs at the end of the main meal + Diet, Water at the end of the main meal+ Diet
- Where
- Iran
- Volunteers
- 81 people
- Sponsor
- Novindiet Clinic
Severe Obesity
VLCD by Enteral Route for Weight Loss
Body weight excess, from overweight to overt obesity, is associated with adverse health outcomes. In view of the time-trends of the obesity epidemic and the related cost burden, the search for effective strategies for weight…
- Trial name
- NEP (NCT01965990)
- Testing
- NEP
- Where
- Italy
- Volunteers
- 364 people
- Sponsor
- San Giuseppe Moscati Hospital
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