Clinical trials: Weight Loss, completed
Obesity, Inflammation
Effects of DHA on Pro-resolving Anti-inflammatory Mediators in Obese Patients Undergoing Weight-loss Treatment
Comparative, randomized, placebo-controlled, single-centre, single-blind clinical trial to assess the effectiveness of providing additional DHA omega-3 fatty acids supplements to increase the levels of pro-resolving and…
- Trial name
- NCT01865448
- Testing
- Omega-3 DHA
- Where
- Spain
- Volunteers
- 34 people
- Sponsor
- Protein Supplies SL
Eating Behavior, Obesity
Effect of Gut-Cued Eating on BMI and Efficacy of Open-Label Placebo to Augment Weight Loss
The study will assess the effect of attending to stomach-cues of hunger and fullness on body weight and any additional benefit provided by open-label placebo.
- Conditions
- Eating Behavior, Obesity, Body Weight, Hunger
- Trial name
- GCE (NCT03850990)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obesity
Effect of Weight Loss on Myocardial Metabolism and Cardiac Relaxation in Obese Adults
Obesity adversely affects myocardial (muscular heart tissue) metabolism, efficiency, and diastolic function. The objective of this study was to determine if weight loss could improve obesity-related myocardial metabolism and…
- Trial name
- NCT00572624
- Testing
- Diet, Gastric bypass surgery
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Knee Osteoarthritis
The Arthritis, Diet, and Activity Promotion Trial
The primary purpose of this study was to determine the effect of dietary weight-loss, exercise training, or a combination of both on physical function in overweight and obese adults with knee osteoarthritis (OA).
- Trial name
- ADAPT (NCT00979043)
- Testing
- Dietary Weight-loss, Exercise
- Where
- United States
- Volunteers
- 318 people
- Sponsor
- Wake Forest University Health Sciences
Pediatric Obesity
Packaging and Disseminating the JOIN for ME Program in Low-Income Settings
One in five children in the United States have obesity, and under-served populations are differentially impacted by both obesity and its related health consequences.
- Trial name
- NCT04647760
- Testing
- JOIN for ME
- Where
- United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity; Excess Calories, Overweight and Obesity
Efficacy and Safety of Litramine in 1 Year Weight Loss Study
To evaluate the efficacy of Litramine in reducing body weight in the context of an energy-restricted diet in overweight and moderately obese subjects
- Conditions
- Obesity; Excess Calories, Overweight and Obesity, Weight Loss
- Trial name
- NCT03227276
- Testing
- Litramine
- Where
- Germany
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Polycystic Ovarian Syndrome, Weight Loss
Comparison of Intermittent Fasting and Caloric Deficit for Weight Loss in Women With Polycystic Ovarian Syndrome
Time restricted feeding (TRF) has been emerging as a potential weight loss strategy that avoids major dietary changes but achieves strong effects. It also improves insulin sensitivity through increased human growth hormone.
- Conditions
- Polycystic Ovarian Syndrome, Weight Loss, Intermittent Fasting
- Trial name
- NCT04452968
- Testing
- intermittent fasting, Caloric restriction
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Karachi Medical and Dental College
Binge Eating, Eating Disorders in Adolescence
Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
This study will develop and test a cognitive-behavioral intervention for adolescents with binge/loss-of-control eating.
- Conditions
- Binge Eating, Eating Disorders in Adolescence, Overweight and Obesity
- Trial name
- NCT04088097
- Testing
- Cognitive-Behavioral Therapy for Adolescent Binge/Loss-of-Control Eating, Control Condition
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Yale University
Obesity & Overweight
Effects of Diet, Exercise, and Electrical Muscle Stimulation in Overweight and Obese Women
This randomized controlled study evaluated the effects of diet, exercise, and electrical muscle stimulation (EMS) on body measurements, blood test results, and appetite in women with overweight or obesity.
- Trial name
- NCT07778550
- Testing
- Individualized Energy-Restricted Diet, Moderate-Intensity Walking, Electrical Muscle Stimulation (EMS)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dicle University
Obesity
Retrospective Chart Review of the 5 & 2 & 2 and 4 & 2 & 1 Plans
The purpose of this study is to retrospectively and systematically review records of overweight and obese Medifast Weight Control Center (MWCC) members who have been assigned to the 5 \& 2 \& 2 Plan or the 4 \& 2 \& 1 Plan for…
- Trial name
- NCT02150837
- Testing
- 5 & 2 & 2 Plan, 4 & 2 & 1 Plan
- Where
- United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Medifast, Inc.
Obesity
Effect of Weight Loss and Exercise on Liver and Muscle Fat in Obese Elderly
The purpose of this study is to determine the effect of weight loss and exercise on liver and muscle fat.
- Trial name
- NCT00779207
- Testing
- weight loss and exercise, weight loss
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity
Evaluation of the Association Between the Menstrual Cycle and Weight Loss in Healthy, Overweight Premenopausal Women
Achievement and maintenance of weight loss in obese individuals has proven difficult. Many hypotheses have suggested potential biological mechanisms to explain why weight loss attempts often fail, and the surrounding obesogenic…
- Trial name
- MENSTRALEAN (NCT01622114)
- Testing
- Evaluation of the Association between the Menstrual Cycle and Weight Loss in Healthy, Overweight Premenopausal Women
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Weight Loss, Other Effects of High Altitude
Substrate Utilization, Exercise Performance, and Skeletal Muscle Response to Energy Deficit and Altitude Acclimatization
This research will evaluate nutrition requirements for missions at high altitude (i.e. >7800 feet above sea level) and the information obtained can be used to optimize nutrient content specifications for combat rations.
- Trial name
- NCT02731066
- Testing
- Standard pro, High pro, carbo bev
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Obesity and Overweight, Hypertriglyceridaemia
Comparison of Cardiometabolic Markers in Individuals With Hypertriglyceridemia With Low and High Weight Loss Responses to an Energy-restricted Diet
Total RNA is extracted from isolated white blood cells, and cDNA is synthesized from these samples. Subsequently, the expression levels of the SIRT1 and leptin receptor genes are determined through quantitative PCR.
- Trial name
- NCT07012226
- Testing
- Low-calorie diet
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Frailty
Ghrelin in Healthy and Frail Older Women
The purpose of this research study is to see if giving women a hormone called "ghrelin" will increase levels of growth hormone in the blood and increase appetite.
- Trial name
- NCT00520884
- Testing
- Ghrelin Infusion - Healthy, Ghrelin Infusion - Frail
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Weight Loss, Blood Pressure
Feasibility & Implementation of a Plant-Based Weight-Loss Program in an Office-Based Setting
This prospective study aims to assess the feasibility and implementation of a plant-based, weight-loss program in an office setting.
- Conditions
- Weight Loss, Blood Pressure, Lipid Disorder, PreDiabetes
- Trial name
- NCT04091516
- Testing
- Low-fat plant-based diet
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Obesity
Effect of Specific Diet and Physical Activity on Weight and/or Fat Loss
The main purpose of this study is to assess metabolic effects (decreased amount of body fat content, insulin sensitivity and lipid profile improvement) of weight loss intervention based on specific life style counseling (low…
- Trial name
- NCT02325804
- Testing
- Lifestyle Counseling
- Where
- Slovakia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Slovak Academy of Sciences
Childhood Obesity
Kaledo Game and The Nutrition Education Prepared According to Health Belief Model
According to the World Health Organization, childhood obesity is the most serious problem of this century. Childhood obesity is an important risk factor for many chronic diseases such as insulin resistance, dyslipidemia…
- Trial name
- NCT04620044
- Testing
- Kaledo game, Education, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Physical Activity
An Adaptive Physical Activity Intervention for Overweight Adults
The purpose of this study is to develop and evaluate an adaptive shaping intervention based on Behavioral Economics and Operant principles to promote physical activity behaviors (adaptive group) and compare to a static physical…
- Trial name
- NCT01793064
- Testing
- Adaptive Intervention (AI), Static Intervention (SI)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Obesity
The EMBER Trial for Weight Management Engagement
This study will test whether EMBER, a self-help tool to increase weight loss treatment engagement, helps veterans engage in Veterans Health Administration (VHA) weight management programs.
- Trial name
- NCT05424081
- Testing
- EMBER, Control
- Where
- 2 sites in United States
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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