Clinical trials: Weight Loss
Obesity
A Study to Assess the Compliance and Impact on Weight of Kurbo, a Pediatric Centered Weight Loss App
Kurbo is a health and fitness app that is targeted toward the pediatric population. It utilizes games and activities to educate children about healthy eating, portion control/size and exercise.
- Trial name
- Kurbo (NCT02880254)
- Testing
- Kurbo, Personal Health Coach
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Obesity
BLOOM-DM: Behavioral Modification and Lorcaserin for Overweight and Obesity Management in Diabetes Mellitus
The purpose of this study is to assess the weight loss effect of lorcaserin during and at the end of 1 year of treatment in overweight and obese patients with Type II diabetes mellitus treated with metformin, sulfonylurea (SFU)…
- Trial name
- NCT00603291
- Testing
- Lorcaserin 10 mg once daily (QD), Lorcaserin 10 mg twice a day (BID)
- Where
- United States
- Volunteers
- 604 people
- Sponsor
- Eisai Inc.
Obese, Cigarette-smoking
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.
- Conditions
- Obese, Cigarette-smoking, Schizophrenia
- Trial name
- NCT02736474
- Testing
- Naltrexone, Bupropion
- Volunteers
- 22 people
- Sponsor
- Shanghai Mental Health Center
Body Weight, Weight Loss
Computer-Based Weight Maintenance in Primary Care
This randomized trial tested the hypothesis that there would be an incremental benefit of personalized coaching and PCP support in an EHR-based intervention designed to help primary care patients maintain recent intentional…
- Conditions
- Body Weight, Weight Loss, Motor Activity
- Trial name
- MAINTAIN-PC (NCT01946191)
- Testing
- 24 months of personalized coaching through the EHR patient portal, with 24 scheduled contacts., Online self-monitoring, Real-time updates to Primary Care physicians
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- University of Pittsburgh
Weight Loss, Starvation
Effect of Caloric Restriction and Protein Intake on Metabolism and Anabolic Sensitivity
The purpose of this study is to determine if an increased protein intake can attenuate the suppression of metabolic and anabolic hormones during caloric restriction
- Trial name
- NCT02945410
- Testing
- Caloric Restriction, Protein, Exercise
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Obesity, Overweight
FitLink: Improving Weight Loss Maintenance by Using Digital Data to Provide Support and Accountability
Most adults in the U.S. are overweight or obese and find maintenance of weight loss difficult. This study is designed to aid in the development of a lifestyle modification program that can facilitate weight loss maintenance…
- Conditions
- Obesity, Overweight, Overweight and Obesity, Weight Loss
- Trial name
- NCT03337139
- Testing
- Gold Standard Behavior Therapy for Weight Loss, Standard Remote Behavior Therapy for Weight Loss, Digital Data Sharing Behavior Therapy for Weight Loss
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Drexel University
Obesity
Evaluation of Pulse Fibre Supplementation on Obesity and the Metabolic Syndrome
The recent dramatic increase in obesity has been linked to a reduction of dietary fibre intake. We hypothesized that supplementing the diet of overweight and obesity adults with pulse fibre will improve their metabolic status…
- Trial name
- NCT01719900
- Testing
- Pulse fibre, Control
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Overweight and Obesity
Preventing Weight Gain Among Those Who Decline Behavioral Weight Loss Treatment (STEADY)
The goal of this pilot trial is to pilot test an intervention to help prevent weight gain or produce weight loss among adults with obesity. Participants are asked to self-weigh on a smart scale for one year.
- Trial name
- STEADY (NCT04751656)
- Testing
- Steady Intervention
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Florida
Obesity, Patient Education
Teaching Obesity Treatment Options to Adult Learners Trial
Obesity is the second leading cause of death in the U.S. The treatment of obesity and its related health issues, including cardiovascular disease and diabetes, exceeds $150 billion annually.
- Conditions
- Obesity, Patient Education, Weight Loss
- Trial name
- TOTAL (NCT03856320)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- VA Office of Research and Development
Cachexia, Non-Small Cell Lung Cancer
Safety and Efficacy of Anamorelin HCl in Patients With Non-Small Cell Lung Cancer-Cachexia (ROMANA 1)
The administration of Anamorelin in patients with Stage III-IV non-small cell lung cancer-cachexia (NSCLC-C) is expected to increase appetite, lean body mass, weight gain, and muscle strength.
- Trial name
- NCT01387269
- Testing
- Anamorelin HCl
- Where
- 60 sites in United States, Belarus and 14 more
- Volunteers
- 484 people
- Sponsor
- Helsinn Therapeutics (U.S.), Inc
Weight Loss
Healthy Immigrant Community: Mobilizing the Power of Social Networks
The objective of this study is to leverage existing social networks for health behavior change relevant to obesity and cardiovascular risk among immigrant populations in Southeast, Minnesota.
- Trial name
- NCT05136339
- Testing
- Community-based mentoring and education sessions
- Where
- United States
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Obesity, Overweight
The Peer Assisted Lifestyle Intervention
The PAL intervention uses a new software tool delivered on tablets to facilitate 5As-based weight management counseling with a peer health coach and the VA PACT healthcare team to promote goal-setting, behavior change, and weight…
- Trial name
- PAL (NCT03163264)
- Testing
- Peer Assisted Lifestyle, Enhanced Usual Care
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- VA Office of Research and Development
Obesity
Integrating Online Weight Management With Primary Care Support
The goal of this project is to adapt an evidence-based online weight management program and integrate it with population management support from primary care practices.
- Trial name
- PROPS (NCT02656693)
- Testing
- Online weight management program, Population health management support
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Brigham and Women's Hospital
Obesity, Apathy
Role of Apathy in the Effectiveness of Weight Loss Interventions
The purpose of this study is to determine whether treating apathy with methylphenidate or medical Crisis counselling will increase adherence to weight loss programs thereby increasing their effectiveness
- Trial name
- NCT00548652
- Testing
- MOVE, medical crisis councelling, methyphenidate
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- VA Nebraska Western Iowa Health Care System
Metabolic Syndrome
A Short Term Evaluation of a Structured Weight Loss Plan in Overweight and Obese Adults
The present study is designed to examine the effect of changes in body weight and related parameters associated with a commercially-available, low-carbohydrate diet plan.
- Trial name
- NCT02774668
- Testing
- "Grab-and-Go" meal plan, "Jump-Start" meal plan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Overweight and Obesity
Novel Executive Function Training for Obesity
Currently, the best behavioral treatments for obesity only work for 50% of adults, and of those who initially succeed, most do not maintain their weight loss.
- Trial name
- NEXT (NCT03724396)
- Testing
- Behavioral Weight Loss - BWL, Novel Executive Function Training - NEXT
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of California, San Diego
Obesity
A Multicenter Study for Pre-Surgical Weight Loss
The purpose of the study is to evaluate the safety and initial efficacy of the EndoBarrier device compared to a diet control in patients who require weight loss prior to their Bariatric surgery.
- Trial name
- NCT00830440
- Testing
- EndoBarrier Device, Diet & Lifestyle Counseling
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Morphic Medical Inc.
Weight Loss
Facebook and Friends: Developing an Effective Online Social Network for Weight Loss
In a pilot randomized trial of 160 obese participants, investigators will test the feasibility of a behavioral weight loss program delivered entirely via Facebook. We will recruit in 2 separate waves of 80 participants each.
- Trial name
- NCT02656680
- Testing
- Continuous Enrollment, Closed Enrollment
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Obesity, Morbid
GLP-1 Therapy for Weight Loss and Improved Glucose Tolerance in Obese Children
The prevalence of severely obese children is on the rise. Behavioral therapies for weight loss are successful in some, but others need more aggressive approaches such as drug therapy.
- Trial name
- NCT00886626
- Testing
- Exenatide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Minnesota
Bleeding, Hemorrhage
Protamine in Cardiac Surgery and Haemostasis
Protamine is used after Cardiopulmonary Bypass (CPB) to reverse the anticoagulant effects of heparin and restore coagulation. Convincing evidence from in-vitro and in-vivo studies suggest that an overdose of protamine has…
- Trial name
- PROTT (NCT01608971)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia