Clinical trials: Weight Loss, completed
Obesity
Vestibular Stimulation to Trigger Adipose Loss (VeSTAL) Clinical Trial
A randomized, double blind sham controlled clinical trial to evaluate the efficacy of vestibular nerve stimulation (VeNS), combined with a lifestyle modification program, compared to a sham control and a lifestyle modification…
- Trial name
- VeSTAL (NCT03640286)
- Testing
- VeSTAL
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Neurovalens Ltd.
Overweight and Obesity
Effect of ANACA3 Slimming Gel on Loss of Abdominal and Thigh Circumferences in Healthy Volunteers
Overweight and obesity is defined, according to the World Health Organization (WHO), by abnormal or excessive accumulation of adipose or fatty tissue that may be harmful to health.
- Trial name
- NCT03685656
- Testing
- Slimming gel
- Where
- France
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Nutravalia
Cachexia; Cancer, Non Small Cell Lung Cancer
A Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) - 1
The goal of this clinical trial was to compare the efficacy and safety of anamorelin HCl (the investigational drug) to that of placebo (tablet with no drug) in patients with advanced non-small cell lung cancer and cachexia…
- Trial name
- NCT03743051
- Testing
- Anamorelin Hydrochloride
- Where
- 72 sites in United States, Bulgaria and 5 more
- Volunteers
- 318 people
- Sponsor
- Helsinn Healthcare SA
Weight Loss
Measuring Eating, Activity and Strength: Understanding the Response -Using Protein
The purpose of the trial is to assess the effects of weight loss on functional status and lean muscle mass in frail, obese older adults (>/= 60) who participate in a 6 month weight reduction intervention.
- Trial name
- MEASUR-UP (NCT01715753)
- Testing
- Protein supplementation, Diet counseling and group education lessons
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- Duke University
Weight Loss
The Personalized Nutrition Study
A person's genetic code is believed to affect how much weight he/she will lose during diets that vary in carbohydrate and dietary fat content.
- Trial name
- POINTS (NCT04145466)
- Testing
- High-fat diet, High-carbohydrate diet
- Where
- United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Pediatric Obesity
PrOtein and WEight Loss in teenageRs
The aim of the proposed study is to provide important data on weight loss efficacy in overweight and obese adolescents on an isocaloric higher protein diet vs a lower protein diet utilizing the U.S.
- Trial name
- POWER (NCT02079831)
- Testing
- Energy Restriction, Higher protein, Lower Protein
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Breast Cancer Female
High Physical Activity During a Weight Loss Intervention for Breast Cancer Survivors and High Risk Women
The purpose of this second pilot study is to extend the feasibility demonstrated in NCT02963740 that the intervention achieves high levels of moderate to vigorous physical activity (MVI PA) and modulates risk biomarkers for…
- Trial name
- NCT03270111
- Testing
- Supervised Exercise, Home-based Exercise, Reduced Energy Diet
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Weight Loss
Effects of a Minimal-Contact Lifestyle Intervention on Physical Activity, Diet, and Body Weight
The purpose of this study is to conduct a pilot randomized controlled trial, to determine whether providing financial incentives for meeting daily step goals (a) increases the daily step counts of participants, (b) increases…
- Trial name
- STEP (NCT02008071)
- Testing
- Daily step goal financial incentive, Standard of Care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Cachexia, Depression
Computerized Questionnaires in Assessing Symptoms, Pain, Depression, and Physical Function in Patients With Metastatic and/or Advanced Locoregional Cancer
RATIONALE: A computer-based system for assessing symptoms may be effective for patients with metastatic or advanced cancer. PURPOSE: This clinical trial is studying how well computerized questionnaires work in assessing symptoms…
- Conditions
- Cachexia, Depression, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00972634
- Testing
- computer-assisted intervention, questionnaire administration, assessment of therapy complications
- Where
- Norway
- Volunteers
- 1,051 people
- Sponsor
- Norwegian University of Science and Technology
Ischemic Heart Disease, Obesity
Copenhagen Study of Obese Patients With Ischemic Heart Disease Undergoing Low Energy Diet or Interval Training
The purpose of the study is to make a head-to-head comparison of weight loss and interval training as methods of secondary prevention in overweight patients with ischemic heart disease.
- Trial name
- CUT-IT (NCT01724567)
- Testing
- Interval Training, Weight Loss
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Eva Prescott
Obesity, Metabolic Surgery
Qsymia as an Adjunct to Surgical Therapy in the Superobese
This study tests the efficacy of the medication, Qsymia, as an adjunct therapy in superobese individuals planning to undergo weight loss surgery.
- Conditions
- Obesity, Metabolic Surgery, Weight Loss, Bariatric Surgery Procedures
- Trial name
- NCT02301416
- Testing
- Phentermine/topiramate, low calorie diet
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wake Forest University Health Sciences
Obstructive Sleep Apnoea, Obesity
Lifestyle Intervention in Obstructive Sleep Apnoea
Obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is a common disorder characterised by interrupted breathing while sleeping. It is associated with cardiovascular problems such as high blood pressure, heart attack and stroke.
- Trial name
- NCT01546792
- Testing
- Combined lifestyle intervention
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis
The Liver Health Study for Patients with NAFLD
The study will investigate whether the level of fat stored in the liver is related to the liver's ability to burn fat.
- Conditions
- Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis, Obesity
- Trial name
- NCT03151798
- Testing
- Phase II: Lifestyle treatment, Phase II: Control treatment, Phase I: Observational studies
- Where
- United States
- Volunteers
- 336 people
- Sponsor
- University of Missouri-Columbia
Overweight and Obesity
Neurocognitive Benefits of a Weight Management Program
This study will assess whether weight loss induced through diet and physical activity can change neural responses to high- and low-calorie food images.
- Trial name
- NCT04202133
- Testing
- WW (formerly Weight Watchers), Waitlist
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Overweight and Obesity
The WEIGH Study: Weighing to Improve and Gain Health
The purpose of this research project is to assess the efficacy of a weight loss intervention for chronic disease prevention that focuses on daily self-weighing as the primary self-monitoring strategy compared to a…
- Trial name
- WEIGH (NCT01369004)
- Testing
- Daily Self-weighing + weekly feedback+ weekly lessons
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Polybrominated Biphenyl Poisoning
Weight Loss Aid in an Exposed Population
This study will explore whether the use of orlistat results in weight loss that is accompanied by a reduction in the body burdens of polybrominated biphenyls (PBB) and other Persistent Organic Pollutants (POPs).
- Trial name
- NCT03582722
- Testing
- Orlistat, Multivitamin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Emory University
Diabete Type 2, Diabetes
The Healthy Eating and Active Living to Reverse Diabetes Pilot Study
The HEAL Diabetes Program is a multicomponent intensive plant-forward healthy eating program designed to reverse diabetes. Several recent studies, most notably the Diabetes UK-funded Diabetes Remission Clinical Trial (DiRECT) in…
- Conditions
- Diabete Type 2, Diabetes, Overweight , Obesity
- Trial name
- HEAL Diabetes (NCT07316569)
- Testing
- Intensive Multicomponent Healthy Eating and Weight Loss Intervention, Enhanced Usual Diabetes Care
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Tennessee
Obesity, Overweight
Effect of Calcium/Vitamin D Supplementation on Body Weight and Fat Loss.
The aim of this study was to assess the effect of calcium/vitamin D supplementation (Caltrate 600 +D®) on body weight loss during a weight-reducing program
- Trial name
- NCT00353054
- Testing
- Caltrate® 600 + D, Weight loss intervention
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Laval University
Obesity; Familial, Pregnancy Related
Pre-Pregnancy Weight Loss and Baby Behavior Study
This study will help researchers learn more about how babies respond to bottle nipples with larger or smaller holes. Researchers guess that infants of mothers with obesity who did not lose weight prior to pregnancy will have the…
- Conditions
- Obesity; Familial, Pregnancy Related, Infant Behavior
- Trial name
- NCT06358729
- Testing
- Typical Nipple, Challenging Nipple
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Inadequate Child Growth
Enhancing Milk Consumption for Improved Nutrition in Rwanda
This study is a mixed-methods cluster-randomized controlled trial in Rwanda designed to measure the impact of a dairy asset transfer program with or without nutrition education promoting the home consumption of dairy milk and…
- Trial name
- NCT03455647
- Testing
- ASF promotion plus Girinka
- Where
- 2 sites in Rwanda
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- RTI International
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