Clinical trials: Weight Loss Maintenance
Obesity
Personalized Nutrition and eHealth: Lifestyle Intervention (LION) Study for Weight Loss Maintenance
Despite standardized intervention strategies, weight loss and weight loss maintenance largely differ from person to person. Factors which may contribute to these individual differences is current object of research.
- Trial name
- LION (NCT04023942)
- Testing
- Weight maintenance intervention
- Where
- Germany
- Volunteers
- 272 people
- Sponsor
- Technical University of Munich
Obesity, Overweight
FitLink: Improving Weight Loss Maintenance by Using Digital Data to Provide Support and Accountability
Most adults in the U.S. are overweight or obese and find maintenance of weight loss difficult. This study is designed to aid in the development of a lifestyle modification program that can facilitate weight loss maintenance…
- Conditions
- Obesity, Overweight, Overweight and Obesity, Weight Loss
- Trial name
- NCT03337139
- Testing
- Gold Standard Behavior Therapy for Weight Loss, Standard Remote Behavior Therapy for Weight Loss, Digital Data Sharing Behavior Therapy for Weight Loss
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Drexel University
Obesity
The Role of No-Calorie Beverages Within a Weight Loss Program
The no calorie drink study is looking for over 300 people to participate. The study is evaluating the effect of no calorie beverages on weight loss and weight maintained over time in people who drink diet beverages every day as…
- Trial name
- NCT01766700
- Testing
- 2 no calorie beverages per day, 2 water beverages per day
- Where
- 2 sites in United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight, Obesity
Effect of Soy Protein and Colorado Diet on Weight Loss and Maintenance
Dietary protein is a key element of most effective weight loss regimens. This study will investigate the effects of consuming soy protein on body composition and cardiometabolic health within the context of an effective weight…
- Conditions
- Overweight, Obesity, Weight Loss
- Trial name
- NCT03248804
- Testing
- Soy group, Non-soy group
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Overweight and Obese Adults, BMI >= 23
Dose Response of Leucine on Muscle Maintenance During Weight Loss
The objective of this research is to determine if there is dose response of leucine on muscle maintenance during 4-week of alternate-day fasting (ADF) on blood parameters, body composition, mood and parameters related to appetite…
- Trial name
- NCT07583875
- Testing
- leucine
- Where
- Singapore
- Volunteers
- 92 people
- Sponsor
- Nanyang Technological University
Obesity
Ketogenic Diets for Weight Loss Maintenance: Impact on Energy Expenditure and Appetite in Individuals With Obesity
The goal of this clinical trial is to investigate whether a Ketogenic Diet (KD) can increase Total Energy Expenditure (TEE), while benefiting appetite, during weight loss maintenance in reduced-obese individuals.
- Trial name
- KETOWEI (NCT06736028)
- Testing
- Diet Therapy, Calorie Restriction, Behavioral Support
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Healthy
Caloric Titration Method of Weight Loss and Maintenance
Study examined the effectiveness of daily self-weighing to prevent age related weight gain.
- Trial name
- NCT03553160
- Testing
- Frequent Self-Weighing
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cornell University
Overweight , Obesity
Phase 2 Study of MWN109 Tablet for Weight-Loss Maintenance in Participants With Overweight or Obesity
This study adopted a randomized, open-label design, aiming to preliminarily explore the weight-loss maintenance effect of MWN109 tablets when administered continuously for 24 weeks in non-diabetic overweight or obese…
- Trial name
- NCT07804797
- Testing
- MWN109 1, MWN109 2
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Breast Cancer, Insomnia
The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
The investigators propose a randomized controlled clinical trial in 250 women with a history of early stage breast cancer who are overweight or obese with insomnia to test whether a brief, cognitive-behavioral intervention for…
- Conditions
- Breast Cancer, Insomnia, Weight Gain
- Trial name
- COIN (NCT05780814)
- Testing
- Cognitive-Behavioral Therapy for Insomnia (CBT-I), Sleep Education Control (EDU)
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Johns Hopkins University
Breast Cancer, Overweight and Obesity
Cancer, Obesity/Overweight and Insomnia Study
This is a randomized pilot study to better understand the relationships among insomnia, weight loss, and breast cancer. This study will assess the effectiveness of a sleep intervention prior to a web- and phone-based weight loss…
- Conditions
- Breast Cancer, Overweight and Obesity, Insomnia
- Trial name
- COIN (NCT03542604)
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Obesity, Overweight
A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)
The main purpose of this study is to evaluate the efficacy and safety of orforglipron on maintenance of body weight reduction in participants who previously completed treatment with injectable tirzepatide (Zepbound) or injectable…
- Trial name
- NCT06584916
- Testing
- Orforglipron
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 376 people
- Sponsor
- Eli Lilly and Company
Childhood Obesity, NAFLD (Non-alcoholic Fatty Liver Disease)
Metabolic Syndrome and Gen-polymorphs Influence on Weightloss Among Children in Treatment for Overweight
Definition: the overall objective is to examine childhood obesity with focus on NAFLD and its treatment. Further, we aimed to investigate the impact of genetic variation on obesity.
- Conditions
- Childhood Obesity, NAFLD (Non-alcoholic Fatty Liver Disease), Hypertension, Hyperlipidemia
- Trial name
- NCT00823277
- Testing
- Chronic care multidisciplinary intervention of childhood obesity
- Where
- Denmark
- Volunteers
- 517 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Obesity
Financial vs. Non-Financial Rewards for Weight Loss and Weight Maintenance
Three of every four Veterans are overweight or obese, and weight loss is associated with reduced morbidity and mortality. The VA MOVE! program for weight loss is moderately effective but only reaches a small percentage of…
- Trial name
- NCT02957539
- Testing
- Financial rewards, Non-Financial rewards
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- VA Office of Research and Development
Obesity
The Use of the Internet to Facilitate Weight Loss and Maintenance.
This project is assessing the effectiveness of using the Internet as a tool to facilitate the maintenance of weight lost in a behavioral weight control program.
- Trial name
- NCT00008827
- Testing
- Behavioral weight loss
- Where
- United States
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Feasibility of a Sleep Improvement Intervention for Weight Loss and Its Maintenance in Sleep Impaired Obese Adults
The primary objective of the proposed study is to develop, deliver and assess the feasibility and adherence to a targeted behavioral sleep intervention for sleep impaired obese patients.
- Trial name
- NCT04243317
- Testing
- Lifestyle & diet, Lifestyle, diet & sleep
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Zayed University
Obesity, Overweight
PILI at Work a 5-Year Controlled Intervention Trial: Testing DVD Versus Group Delivery of a Weight-Loss Maintenance Intervention in Native Hawaiian- Serving Worksites
The PILI @ Work project is a 5 year randomized control trial to adapt a weight loss program for the employees of Native Hawaiian-serving organizations in Hawai'i.
- Conditions
- Obesity, Overweight, Weight Loss, Weight Loss Maintenance
- Trial name
- P@W (NCT01652989)
- Testing
- Weight loss maintenance intervention face-to-face, Weight loss maintenance intervention delivered via DVD
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Hawaii
Obesity
What is the Impact of Probiotics on Weight Loss Maintenance in Individuals With Obesity?
Weight loss maintenance is the biggest challenge in obesity management, with the majority of weight-reduced individuals experiencing weight regain.
- Trial name
- NCT03287726
- Testing
- probiotics
- Where
- Norway
- Volunteers
- 76 people
- Sponsor
- Norwegian University of Science and Technology
Overweight and Obesity
Effect of the LEVAmethod by Bertz et al © in Subjects With Overweight or Obesity in Primary Health Care.
This study evaluates weight loss effect of the method LEVA by Bertz et al in subjects with overweight or obesity that are remitted to Primärvårdens Dietistenhet.
- Trial name
- LEVA-POP (NCT04184479)
- Testing
- LEVAmethod by Bertz et al
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Weight Trajectory
Gamma-linolenic Acid Supplementation Study
Weight regain following weight loss is common. In rodent models of obesity and pilot studies in humans, increasing membrane arachidonic acid content improves fuel partitioning and prevents weight regain.
- Trial name
- GLASS (NCT04481724)
- Testing
- gamma-linolenic acid
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- Virta Health
Cancer, Cancer Cachexia
A Fish Oil Supplement to Maintain Body Weight in Patients With Disease-Related Weight Loss
The purpose of this study is to evaluate the safety and effectiveness of fish oil supplements in maintaining weight in people with disease-related weight loss and/or cachexia.
- Conditions
- Cancer, Cancer Cachexia, Chronic Obstructive Pulmonary Disease, Chronic Heart Failure
- Trial name
- NCT00094562
- Testing
- Fish oil supplement
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins