Clinical trials: Weight Loss Trial
Obesity
Effects of Self-conditioning Techniques in Promoting Weight Loss in Patients With Obesity. A Randomized Controlled Trial
The investigators hypothesized that hypnosis is an alternative technique that could be applied to help patients with obesity to lose weight.
- Trial name
- NCT02978105
- Testing
- self-conditioning techniques, standard care (diet, exercise and behavioral therapy)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Turin, Italy
Obesity, Obesity (Body Mass Index >30 kg/m2)
ENLIGHT Trial: ESG With Fundal Mucosal Ablation
The ENLIGHT Trial is a single-center, randomized controlled trial evaluating whether adding fundal mucosal ablation (FMA) to endoscopic sleeve gastroplasty (ESG) improves weight loss and metabolic outcomes in adults with obesity.
- Trial name
- NCT07792226
- Testing
- Endoscopic Sleeve Gastroplasty (ESG), Fundal Mucosal Ablation
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- West Virginia University
Cachexia, Head and Neck Cancer
Low Antioxidant Diet in Controlling Cachexia in Patients With Oropharyngeal Cancer Receiving Chemotherapy and Radiation Therapy
RATIONALE: Eating a diet that is low in antioxidants may control cachexia in patients with oropharyngeal cancer. PURPOSE: This randomized phase I trial is studying the side effects of a low antioxidant diet in controlling…
- Conditions
- Cachexia, Head and Neck Cancer, Weight Changes
- Trial name
- NCT00486304
- Testing
- ADD
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Weight Cycling, Obesity & Overweight
Effect of Meal Frequency on Diet Self-Efficacy and Perceived Stress in Women With Weight Cycling
The World Health Organization (WHO) defines obesity as abnormal or excessive fat accumulation in the body that may adversely affect health.
- Conditions
- Weight Cycling, Obesity & Overweight, Dietary Self-efficiacy, Perceived Stress
- Trial name
- NCT07582952
- Testing
- 3-meal diet plan, A dietary intervention comprising 3 main meals and 3 snacks
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara Medipol University
Overweight and Obesity
A Theory-based Digital Intervention to Promote Weight Loss and Weight Loss Maintenance
Obesity can severely reduce quality and longevity of life and there is an urgent need to help people lose weight and maintain weight loss long term.
- Trial name
- NCT04291482
- Testing
- Choosing Health Intervention, Choosing Health Control
- Where
- Poland
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Bariatric Surgery Patients
Is Resistance Exercise More Effective Than Endurance in Reducing Obesity Relapse in Post-bariatric Surgery Patients
The goal of this clinical trial is to compare the effects of resistance exercise and endurance in post-bariatric surgery patients with insuficcient weight loss.
- Trial name
- BariOptimize (NCT05632718)
- Testing
- Exercise
- Where
- Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Obesity
A Randomized Trial Comparing Two Doses of Portion-Controlled Foods Within a Primary Care Weight Loss Program
We hypothesize that individuals provided with 1 meal per day of portion-controlled foods (shakes and prepared entrees) will lose as much weight as individuals provided with 2 meals per day of portion-controlled foods.
- Trial name
- PCPCWLS (NCT00907660)
- Testing
- Weight loss counseling, Portion-Controlled Foods
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kaiser Permanente
Obesity
Lifestyle Modification and Lorcaserin for Weight Loss Maintenance
The proposed 12-month randomized controlled trial will assess the efficacy of lifestyle counseling, combined with lorcaserin (10 mg BID) or placebo, in maintaining weight loss achieved during a prior 14-week dietary run-in.
- Trial name
- NCT02388568
- Testing
- Lorcaserin
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- University of Pennsylvania
Obesity, Overweight
Project THRIVE: Evaluating Different Approaches to Dietary Self-Monitoring for Weight Loss
This randomized pilot trial will compare two approaches to dietary self-monitoring for weight loss in the context of a low-intensity, remotely-delivered lifestyle modification program.
- Trial name
- NCT05241353
- Testing
- Reduced Frequency Self-Monitoring, Full-Frequency Self-Monitoring, Standard Behavioral Treatment
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Drexel University
Hip Osteoarthritis, Overweight and Obesity
Effects of a Weight Loss Program in People With Hip Osteoarthritis
This randomised controlled trial will compare the effects of a weight loss and exercise program to exercise only on clinical outcomes in 100 people with hip osteoarthritis (OA) and overweight or obesity.
- Trial name
- ECHO (NCT04825483)
- Testing
- Weight loss, Exercise
- Where
- Australia
- Volunteers
- 101 people
- Sponsor
- University of Melbourne
Obesity & Overweight
Trial of Food Is Medicine Approaches for Obesity Treatment in Adults With Food Insecurity
The goal of this clinical trial is to learn if increased access to healthy foods, combined with behavioral weight loss (BWL) interventions, results in greater weight loss for adults with obesity and food insecurity.
- Trial name
- EatWell Rx (NCT07396805)
- Testing
- BWL, VOUCHER, HOME
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Knee
Changes in Skin Autoflouresence Following Weight Loss and Maintenance Using Liraglutide in Knee Osteoarthritis
This is sub-study to a randomised, double blind, placebo-controlled, parallel group, and single-centre trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis…
- Trial name
- NCT02910570
- Testing
- Liraglutide 3 mg (Saxenda)
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Parker Research Institute
Obesity, Hypercholesterolemia
Improving the Management of Obesity in Primary Care Practice (The Power-UP Trial)
The purpose of the study is to compare three methods of achieving weight loss in primary care medical practice. The study will be conducted in six primary care practices.
- Conditions
- Obesity, Hypercholesterolemia, Metabolic Syndrome, Hypertension
- Trial name
- Power-UP (NCT00826774)
- Testing
- Usual Care, Brief Lifestyle Counseling, Enhanced Brief Lifestyle Counseling
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Obesity, Glomerulopathy
Dietary Intervention in Obesity-related Glomerulopathy
Obesity-related glomerulopathy (ORG) is a silent comorbidity associated with obesity whose incidence is increasing in parallel to the obesity epidemic.
- Trial name
- ORG-VLCD-2022 (NCT05294770)
- Testing
- Optisource® Plus: Very Low Calorie Diet treatment, Hypocaloric Mediterranean Diet
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud
Randomized Versus Placebo, Controlled
Effect of the Alpha-galacto-oligasaccharides on Weight Loss in Overweight or Moderately Obeses Adults : A Randomized Controlled Double Blinded Trial Versus Placebo
Clinical intervention on overweight or moderately obeses adults. The objective of this trial is to demonstrate the superior eficacy of Alphagos to placebo on weight loss during a low-calorie diet of 12 weeks.
- Conditions
- Randomized Versus Placebo, Controlled, Double Blind
- Trial name
- NCT02228746
- Testing
- Alpha-galacto-oligosaccharides
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Olygose
OSA - Obstructive Sleep Apnea
Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients
Study Overview: Obesity and Obstructive Sleep Apnea (OSA) are strongly linked. This study aims to understand whether a procedure called Endoscopic Sleeve Gastroplasty (ESG), along with lifestyle changes like healthy eating and…
- Trial name
- OSA (NCT07082608)
- Testing
- Endoscopic Sleeve Gastropathy, Lifestyle Modification alone
- Where
- India
- Volunteers
- 74 people
- Sponsor
- Asian Institute of Gastroenterology, India