Clinical trials: Weight Loss Trial
Obesity, Adiposity
The Effects of Supplementation of Conjugated Linoleic Acid on Body Fat Reduction
This is a double-blinded randomized controlled trial, to evaluate the effectiveness of daily supplementation of 3.2 g CLA on body fat reduction and lipid profile in overweight or obese Chinese adults, during a lifestyle…
- Trial name
- NCT03915808
- Testing
- Conjugated linoleic acid group, Sunflower oil group
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Jiaomei Yang
Weight Loss
Evaluation of Efficacy of a Cashew Apple Extract on Weight Management and Associated Metabolic Risk Factors in Overweight/Obese Volunteers
The purpose of this study is to assess the efficacy and safety of a cashew apple extract on weight management and associated metabolic risk factors in overweight/obese volunteers, versus placebo, after 12 weeks of treatment.
- Trial name
- NCT02493140
- Testing
- Cashew apple extract (Cashewin)
- Where
- France
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Dialpha
Skin; Excess
Techniques for Abdominoplasty After Massive Weight Loss
Excess skin on the abdomen is a common problem for many individuals after massive weight loss. The surgical procedure of abdominoplasty is intended to remove excess skin and improve the shape of the torso in abdomen, in order to…
- Trial name
- NCT04805424
- Testing
- Lipo-abdominoplasty, Abdominoplasty
- Where
- Sweden
- Sponsor
- Karolinska University Hospital
Cardiometabolic Risk, Weight Loss
Effects of Caloric Restriction and Exercise on Body Weight, Immune Function, and Intestinal Flora
The purpose of this study is to estimate the effects of caloric restriction and exercise on body weight, cardiovascular metabolic markers, immune function, and intestinal flora among college students, as well as the underlying…
- Conditions
- Cardiometabolic Risk, Weight Loss, Immune System, Intestinal Microbiome
- Trial name
- NCT04275440
- Testing
- Exercise, Caloric restriction
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Obesity
Adults Regulating Their Weight Everyday With Mobile Internet Support
Adults Regulating Their weight Everyday with Mobile Internet Support (ARTEMIS) is a randomised controlled trial evaluating the effectiveness of a mobile app based weight loss intervention designed to increase self-regulation in…
- Trial name
- ARTEMIS (NCT05787652)
- Testing
- ARTEMIS mobile app
- Where
- United Kingdom
- Volunteers
- 1,294 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Advanced Cancer, Cachexia
Multimodal Treatment Strategy for Cancer Cachexia
The primary aim of this proposal is to present a novel, multimodal treatment strategy for increasing lean body mass in individuals with cancer who experience cachexia between baseline and day 29 (+/- 3 days).
- Trial name
- NCT00625742
- Testing
- Graded Resistance Training, Aerobic Exercise, Melatonin
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- M.D. Anderson Cancer Center
Metabolic Associated-dysfunction Steatotic Liver Disease (MASLD), Metabolic Associated-dysfunction Steatohepatitis (MASH)
Behavioral Lifestyle Intervention for Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) in Adults
The goal of this randomized control trial study is to compare an acceptance-based weight loss program with an occupational therapy behavioral lifestyle modification intervention in adults with metabolic associated-dysfunction…
- Trial name
- NCT06121999
- Testing
- Standard of care acceptance-based behavioral weight loss program, Occupational therapy dietary and lifestyle modifications
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Grand Valley State University
Overweight
Effect of a Dietary Supplement on Weight Loss and Psychological Wellbeing in Overweight Individuals
The aim of this randomized, parallel, two-arm, placebo-controlled, double-blind, multicenter clinical trial is to evaluate the efficacy of a dietary supplement on weight loss and psychological well-being in overweight individuals.
- Trial name
- NCT05758363
- Testing
- Consumption of dietary supplement., Consumption of control product
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Obesity
Integrating Small Changes and Positive Psychology to Improve Treatment Readiness: A Weight Loss Trial
The study is designed to compare short- and long-term changes in body weight (kg) and subjective well-being in adult females with obesity who have been randomized to receive one of two 6-month treatment conditions: INSPIRE or…
- Trial name
- INSPIRE (NCT04487158)
- Testing
- Small Changes, INSPIRE
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Overweight, Obesity
Evaluation of the Planetary Health Diet Included in a Lifestyle Program in Overweight or Obese Mexican Adults.
The EAT-Lancet Commission proposed the planetary health diet as a strategy to achieve health and sustainability goals. Currently, its effect in the treatment of obesity has not been evaluated.
- Trial name
- NCT05309044
- Testing
- Planetary Health Diet Group, Low-fat diet group, Waiting list group
- Where
- Mexico
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Sonora
Type 2 Diabetes Mellitus, Overweight
Lifestyle Modification for Obesity-Related Type 2 Diabetes
Dietary carbohydrate is the major determinant of postprandial glucose levels, and preliminary evidence suggests that low carbohydrate diets improve glycemic control when accompanied by weight loss.
- Conditions
- Type 2 Diabetes Mellitus, Overweight, Obesity
- Trial name
- NCT00415688
- Testing
- Low carbohydrate, ketogenic diet, Low glycemic index, reduced calorie diet
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Robert C. Atkins Foundation
Weight Loss, Obesity
The Impact of Abdominal Body Contouring Surgery on Physical Function After a Massive Weight Loss (BCSP)
Obesity is a growing chronic medical condition in which as of 2015, a total of 107.7 million children and 603.7 million adults were considered obese and since 1980 the prevalence of obesity has doubled in more than 70 countries.
- Trial name
- BCSP (NCT04516473)
- Testing
- Abdominal Body Contouring
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- University of British Columbia
Pre-diabetes
A Community-based Weight Loss Programme for Chinese Overweight Adults With Pre-diabetes
Type 2 diabetes (T2DM) is a serious chronic condition and one of the world's fastest growing health problems. The onset of T2DM is gradual, with most individuals progressing through a state of pre-diabetes.
- Trial name
- NCT03609697
- Testing
- group-based lifestyle intervention, Minimal intervention (SMS intervention)
- Where
- Hong Kong
- Volunteers
- 180 people
- Sponsor
- The University of Hong Kong
Malnutrition, Child
Effectiveness of a Positive Deviance Program in Reducing Childhood Undernutrition
Globally, childhood malnutrition remains a public health concern. Malnutrition can be diverse from undernutrition to overnutrition.
- Trial name
- NCT04688515
- Testing
- Nutrition program developed using positive deviance approach
- Where
- Malaysia
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Abdominal Obesity-Metabolic Syndrome
Effect of a Meal Replacement on Weight Loss Obesity Patients With Metabolic Syndrome
The purpose of this study is to determine whether meal replacement, SlimWell ®, is effective in the treatment of obesity patients with metabolic syndrome.
- Trial name
- SlimWell (NCT02626741)
- Testing
- meal replacement group, control group
- Where
- Thailand
- Volunteers
- 138 people
- Sponsor
- Mahidol University
Obesity
An Investigational Drug Study to Assess Weight Loss in Obese and Overweight Patients (0364-037)(TERMINATED)
A 1 year worldwide study in obese and overweight patients to assess the safety and effect on body weight of an investigational weight loss drug.
- Trial name
- NCT00384605
- Testing
- taranabant
- Volunteers
- 1,000 people
- Sponsor
- Merck Sharp & Dohme LLC
Obesity, Food Insecurity
TARGETing Healthy Weight Loss in the Context of Food Insecurity
This pilot and feasibility study will collect information from food insecure, as well as food secure, women with obesity to detail their desires and needs for healthy weight reduction.
- Conditions
- Obesity, Food Insecurity, Food Security, Body Weight
- Trial name
- TARGET P&F I (NCT05601804)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Cachexia, Neoplasms
Multimodal Intervention for Cachexia in Advanced Cancer Patients Undergoing Chemotherapy
Cancer cachexia is a multi-factorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive…
- Trial name
- MENAC (NCT02330926)
- Testing
- standard care, nutritional supplements and advice, home-based self-assisted exercise program
- Where
- 17 sites in United States, Canada and 4 more
- Volunteers
- 221 people
- Sponsor
- Norwegian University of Science and Technology
Obesity
Efficacy and Safety of Low-Carbohydrate Diet Combined With Probiotics for Weight Loss in Male Obese Patients.
Over the years, increasing obesity prevalence represents an important threat to national and global public health. Many strategies studied for weight loss have reported that low-carbohydrate diets showed beneficial effects on…
- Trial name
- NCT04886778
- Testing
- Low-carbohydrate diet, Probiotic compound preparations
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Sun Jia
Asthma, Obesity
Exercise Training to Lose Weight in Obese Asthmatics
Obese asthmatics have more severe symptoms, reduced lung function, poorer quality of life and a reduced response to inhaled corticosteroid medication compared to non-obese asthmatics.
- Trial name
- NCT02188940
- Testing
- Dietary, Education Program, Behavioral Therapy
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- University of Sao Paulo General Hospital