Clinical trials: Weight Management
Weight Management, Obesity
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
This study aims to elucidate the differences in the gut microbiome functional activity and metabolome in adult premenopausal women with distinctive fitness levels and BMIs (with obesity, w/o obesity).
- Conditions
- Weight Management, Obesity, Exercise, Women
- Trial name
- FITGut-W (NCT06691100)
- Testing
- Aerobic Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- George Washington University
Lifestyle, Healthy, Weight Management
Implementing Strategies for Eating Behaviour Modification Based on Portion Control
This is a pre-post intervention study designed to evaluate the feasibility of a self-applied weight management intervention based on portion control.
- Conditions
- Lifestyle, Healthy, Weight Management, Behavior Change
- Trial name
- PORTIONS-4 (NCT06519539)
- Testing
- PORTIONS-4 behaviour change strategies
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Metabolic Health, Weight Management
A Clinical Trial to Evaluate the Effects of A Supplement on Supporting Signs of Metabolic Health
This study evaluates the effects of the Love Wellness supplement Hello Burn Activate on supporting metabolic health in adult females.
- Conditions
- Metabolic Health, Weight Management, Body Confidence, Gut Health
- Trial name
- NCT07765394
- Testing
- Hello Burn Activate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Poor Energy Levels, Poor Metabolism
A Clinical Trial to Evaluate the Effects of a Supplement on Supporting Signs of a Healthy Metabolism
This study evaluates the effects of Love Wellness Energize, a dietary supplement, on supporting signs of a healthy metabolism in women aged 25-45 who report poor energy levels, perception of poor metabolism, difficulty with…
- Conditions
- Poor Energy Levels, Poor Metabolism, Difficulty With Weight Management, Bloating
- Trial name
- NCT07765407
- Testing
- Love Wellness Energize
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Love Wellness
Physical Symptom Distress, Weight Management
A Self-management Based Survivorship Intervention for Chinese Cancer Survivors
This study, using a sequential multiple assessment randomized controlled trial (SMART) approach, will evaluate a cancer survivorship care intervention on physical symptom distress, weight management, self-efficacy in managing…
- Conditions
- Physical Symptom Distress, Weight Management, Neoplasms
- Trial name
- NCT05534386
- Testing
- Cancer survivorship care intervention, Step-up targeted personalized intervention, First stage control intervention
- Where
- 7 sites in Hong Kong
- Volunteers
- 486 people
- Sponsor
- The University of Hong Kong
Chronic Management of Body Weight
A Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Tablets in Overweight or Obese Subjects
This study aims to evaluate the efficacy and safety of HRS9531 tablets compared with placebo in reducing body weight in overweight or obese subjects after 52 weeks of treatment.
- Trial name
- NCT07670884
- Testing
- HRS9531 Tablet
- Where
- 2 sites in China
- Volunteers
- 675 people
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Endometrial Cancer Survivors, Weight Management
Weight Loss Management in Endometrial Cancer Survivors
This study is being done to understand how oncologists can engage a multidisciplinary team to help endometrial cancer survivors with obesity to engage in a weight management program and potentially start a weight loss medication.
- Conditions
- Endometrial Cancer Survivors, Weight Management, Early Stage Endometrial Cancer
- Trial name
- ECS Weight (NCT06877572)
- Testing
- Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Kansas Medical Center
Gut Health, Body Composition
A Clinical Trial to Evaluate the Effects of Cowboy Colostrum on Gut Health, Body Composition, Hair Growth, and Skin Appearance
This study evaluates the effects of Cowboy Colostrum bovine colostrum powder on gut health, body composition, hair growth, and skin appearance in generally healthy adults aged 21-47 with concerns in these areas.
- Conditions
- Gut Health, Body Composition, Hair Growth, Skin Appearance
- Trial name
- NCT07756866
- Testing
- Cowboy Colostrum
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Cowboy Colostrum
Obesity, Overweight, or Chronic Weight Management
A Phase 2b, Dose-range Finding Study of the Efficacy and Safety of Multiple Doses of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity
This study is a randomized, double-blind, placebo-controlled, dose-range finding study of the efficacy, safety, tolerability, PK, and PD of multiple doses of aleniglipron in participants living with overweight or obesity with at…
- Trial name
- ACCESS (NCT06693843)
- Testing
- Aleniglipron
- Where
- 39 sites in United States
- Volunteers
- 230 people
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Weight Management, Obesity Prevention
Advancing Biopsychosocial Care Training Initiative
This project will compare two training approaches for US Preventive Services Task Force recommended obesity care in Federally Qualified Health Centers (FQHC) across four aims.
- Conditions
- Weight Management, Obesity Prevention, Obesity and Obesity-related Medical Conditions, Obesity and Overweight
- Trial name
- ABC Initiative (NCT07049861)
- Testing
- Comprehensive Multidisciplinary Obesity Care, Implementation as Usual Control
- Where
- United States
- Volunteers
- 6,200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obesity, Overweight
Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)
Study GSBR-1290-12 is a Phase 3 pivotal, multicenter, global, randomized, placebo-controlled, double-blind study to investigate the long-term efficacy, safety, and tolerability of 3 maintenance doses of aleniglipron once daily…
- Conditions
- Obesity, Overweight, Chronic Weight Management
- Trial name
- NCT07654361
- Testing
- Aleniglipron
- Where
- 71 sites in United States
- Volunteers
- 3,600 people
- Sponsor
- Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics
Weight Management
A Study of YP05002 in Healthy Participants
This is a phase I, randomized, double-blind, placebo-controlled, single and multiple ascending dose study to evaluate the safety, tolerability, pharmacokinetics, efficacy, food effect of YP05002 Tablets in healthy participants
- Trial name
- NCT07089823
- Testing
- YP05002
- Where
- Australia
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Yaopharma Co., Ltd.
Obesity and Overweight, Obese Adolescents
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
The goal of this clinical trial is to learn if the drug semaglutide changes markers of disease risk as it relates to weight in children ages 12-15 years old who are obese (class 2 or 3).
- Conditions
- Obesity and Overweight, Obese Adolescents, Weight Management, Weight Loss
- Trial name
- MODERN (NCT06967389)
- Testing
- Ozempic®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- John Bauer
Obesity & Overweight, Weight Management
Family-Based Weight Wellness Treatment Through Food is Medicine and Group Medical Visits in Pediatric and Adult Primary Care
The proposed project aims to implement and evaluate a novel, family-based lifestyle medicine intervention integrating group Shared Medical Appointments (SMAs) for parents and adolescents with a twelve-month medically tailored…
- Trial name
- NCT07717658
- Testing
- Culinary medicine classes, Medically Tailored Groceries, Shared Medical Appointments
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Tufts University
Chronic Weight Management
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ASC30 Injection in Participants With Obesity
This randomized, double-blind, placebo-controlled single ascending dose (SAD)/ multiple ascending dose (MAD) study is designed to evaluate the safety, tolerability, pharmacokinetics, and efficacy of ASC30 injection
- Trial name
- NCT06679959
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Ascletis Pharma (China) Co., Limited
Adult Obesity, Weight Management
MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial
The primary objective of this trial is to evaluate the effect of oral ECC4703 on body weight reduction and in a sub-study on liver fat content as assessed by change in magnetic resonance imaging proton density fat fraction…
- Trial name
- NCT07505303
- Testing
- ECC4703, Semaglutide
- Where
- 15 sites in United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Eccogene
Weight Management, Type 2 Diabetes
A Clinical Study to Evaluate the Effect of Different Dosing Conditions on the Pharmacokinetics of HRS9531 Tablets in Healthy Participants
The study is being conducted to evaluate the effects of different dosage regimen on the pharmacokinetics of HRS9531 tablets in healthy subjects.
- Trial name
- NCT06506175
- Testing
- HRS9531 tablets
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Weight Management
White Mulberry Leaf Extract for Metabolic Health in Overweight Adults Taking Metformin
This study tests whether a mulberry leaf extract can help adults with early cardiometabolic risk lose more weight while taking metformin.
- Trial name
- NCT07451639
- Testing
- Mulberry Leaf Extract
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Weight Management
TTM-Based Intervention for Weight Management Among High School Female Students
To examine the efficacy of a Transtheoretical Model (TTM)-based intervention in improving weight management behaviors. 1. To identify if the student age, body mass index (BMI) and socioeconomic status can predict WMB. 2.
- Trial name
- TTM-WMHSFS-RCT (NCT07604649)
- Testing
- Transtheoretical Model (TTM)-Based Behavioral Intervention for Weight Management
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Weight Management
CORE Study - Research Into Weight Management Services in the UK
Weight management services (previously known as Tier 3 services) represent a multidisciplinary specialist approach, available in community or secondary care settings.
- Trial name
- CORE (NCT07559409)
- Where
- United Kingdom
- Volunteers
- 41,000 people
- Sponsor
- Society for Endocrinology