Clinical trials: Weight Reduction
Obesity, Obesity, Abdominal
Acupoint Catgut Embedding With Laser Acupuncture for Weight Loss in Adults With Obesity
Acupoint catgut embedding and laser acupuncture have each been studied as treatments for obesity in adults, but the two have not been evaluated in combination, and few trials have measured anthropometric, biochemical, and blood…
- Conditions
- Obesity, Obesity, Abdominal, Overweight
- Trial name
- NCT07770893
- Testing
- Acupoint catgut embedding, Active laser acupuncture, Dietary and exercise counseling
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei City Hospital
Deep Venous Thrombosis
Low-Molecular-Weight Heparin (LMWH) for Deep Venous Thrombosis (DVT) Prophylaxis
1. The use of LMWH following open reduction and internal fixation of ankle fractures will reduce the number of thrombi formed. 2. The rates of clinically significant DVT will be equivalent between two groups.
- Trial name
- NCT01029821
- Testing
- Low-Molecular-Weight Heparin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Obesity, Overweight
Environmental and Acceptance-Based Innovations for Weight Loss Maintenance
The major goal of this project is to evaluate an innovative approach to obesity involving modification of the home environment. The project also will evaluate if home environment modification is more effective when supplemented…
- Conditions
- Obesity, Overweight, Weight Loss
- Trial name
- ENACT (NCT01858714)
- Testing
- Behavior Therapy for Weight Loss, Behavior Therapy + Environment, Acceptance-based Behavior Therapy + Environment
- Where
- United States
- Volunteers
- 238 people
- Sponsor
- Drexel University
Obesity, Smoking Cessation
A Multiple Health Behavior Change (MHBC) Intervention for Weight Loss and Smoking Cessation for Pre-Bariatric Surgery Patients
The purpose of this research study is to evaluate a multiple health behavior change intervention for weight loss and smoking cessation using medication (Naltrexone + Bupropion) and behavior therapy in adults seeking bariatric…
- Conditions
- Obesity, Smoking Cessation, Bariatric Surgery Patients
- Trial name
- NCT07398404
- Testing
- Naltrexone hydrochloride, Bupropion Hydrochloride Extended-release, Cognitive-Behavioral Therapy
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Medical University of South Carolina
Obesity
A Prospective, Randomized Multicenter Study to Evaluate the Safety and Efficacy of the ReShape Duo™ Intragastric Balloon System in Obese Subjects
The REDUCE Pivotal Trial is a pivotal clinical study designed to develop valid scientific evidence regarding the safety and effectiveness of the ReShape Duo® as an adjunct to diet and exercise in the treatment of obese subjects…
- Trial name
- NCT01673698
- Testing
- ReShape Duo balloon, Diet counseling, Exercise counseling
- Where
- 8 sites in United States
- Volunteers
- 326 people
- Sponsor
- ReShape Lifesciences
Obesity
BEYOND Weight Loss Maintenance Study
A study to determine the effectiveness of two weight loss maintenance interventions in Counterweight Plus, a structured weight management programme.
- Trial name
- NCT02683798
- Testing
- Continuous energy restriction, Intermittent energy restriction
- Where
- 3 sites in United Kingdom
- Volunteers
- 63 people
- Sponsor
- NHS Greater Glasgow and Clyde
Polycystic Ovary Syndrome, Overweight
Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
The purpose of this study is to determine the effects of stress reduction on glucose, blood pressure, quality of life and overall health and well-being in overweight or obese women, either with Polycystic Ovary Syndrome (PCOS) or…
- Conditions
- Polycystic Ovary Syndrome, Overweight, Obesity, Stress, Physiological
- Trial name
- NCT01464398
- Testing
- Stress reduction, Stress reduction with Health education
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Milton S. Hershey Medical Center
Obesity
Weight Loss in Pre-diabetic, Obese Women
This is a six (6) month, single center, randomized, double-blind, parallel, controlled-feeding weight-loss study comparing two dietary groups (triglyceride and olestra) in pre-diabetic obese women.
- Trial name
- NCT00686816
- Testing
- Low calorie diet, Olestra
- Where
- Russia
- Volunteers
- 80 people
- Sponsor
- Procter and Gamble
Metabolic Syndrome
Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome
Background. The prevalence of type 2 diabetes mellitus (T2D) in the world is constantly increasing. Treatment of T2D is complicated by arterial hypertension and obesity (metabolic syndrome - MS).
- Trial name
- NCT06410352
- Testing
- Semaglutide, Empagliflozin, Minigastric bypass, Analimentary detoxication
- Where
- Kazakhstan
- Volunteers
- 220 people
- Sponsor
- University Medical Center, Kazakhstan
Weight Loss
Assessing the Bite Counter
This study is designed to test the usability of the Bite Counter in an attempt to reduce participants' daily bites while also increasing their daily steps.
- Trial name
- NCT02763358
- Testing
- Bite Counter
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obesity
Increasing Uptake of Behavioral Weight Loss Programs Among Primary Care Patients
This pilot trial will test feasibility and acceptability of a primary care-based intervention that aims to increase the portion of patients who enter evidence-based behavioral weight loss treatment.
- Trial name
- NCT02708121
- Testing
- Motivational Intervention, Comparator Intervention
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Florida
Obesity in Diabetes, Obesity/Therapy
Semaglutide Treatment in Type 1 Diabetes
The goal of this clinical trial is to investigate the efficacy of semaglutide on body weight, insulin dose requirements and improvements in glucose control and safety aspects in regards to risk of hypoglycemia and diabetic…
- Conditions
- Obesity in Diabetes, Obesity/Therapy, Type 1 Diabetes Mellitus (T1DM), Insulin Sensitivity/Resistance
- Trial name
- OBES1TY (NCT06909006)
- Testing
- Semaglutide 2.4mg
- Where
- Denmark
- Volunteers
- 122 people
- Sponsor
- Nordsjaellands Hospital
Obesity
Evaluation of a SlimFast Internet Behavioral Weight Loss Program
The Internet has been used effectively in behavioral weight loss programs. Most of these programs have involved a therapist who provides email counseling.
- Trial name
- NCT00200304
- Testing
- Internet weight loss with SlimFast and human counseling, Internet weight loss with SlimFast and computer counseling, Internet weight loss program with SlimFast
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- The Miriam Hospital
Obesity, HIV-1-infection
Semaglutide's Efficacy in Achieving Weight Loss for Those With HIV
The prevalence of obesity is rising worldwide, both in low- and high-income countries, including people with HIV (PWH). Semaglutide's efficacy in achieving weight loss in obese PWH is still unexplored.
- Trial name
- SWIFT (NCT04174755)
- Testing
- Semaglutide Injectable Product, Standard of care
- Where
- Ireland
- Volunteers
- 80 people
- Sponsor
- University College Dublin
Weight Loss, Metabolic Syndrome
The Impact of Time Restricted Feeding (TRF) in Improving the Health of Patients With Metabolic Syndrome
The investigators intend to measure the health impact of a dietary intervention known as time restricted feeding (TRF) on patients with metabolic syndrome (three or more of: increased waist circumference, abnormal cholesterol…
- Conditions
- Weight Loss, Metabolic Syndrome, Overweight and Obesity
- Trial name
- NCT03182985
- Testing
- Time Restricted Feeding
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of California, San Diego
Breast Cancer
Behavioral Weight Loss and Exercise After Treatment (BEAT)
Overweight and physically inactive breast cancer survivors are at increased risk of breast cancer recurrence and mortality. Cancer treatment-related changes that likely mediate weight loss and exercise success include the long…
- Trial name
- BEAT (NCT02052115)
- Testing
- 12 month exercise and weight loss intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Vermont
Obesity, Bariatric Surgery Candidate
The Collateral Impact of Bariatric Surgery on Families
This proposal is designed to examine the impact of bariatric surgery on the health of patients and their families. The shared environment of spouses/cohabitating partners suggests that patients' families are exposed to the…
- Conditions
- Obesity, Bariatric Surgery Candidate, Weight Loss
- Trial name
- Collateral (NCT02021630)
- Testing
- Outcomes
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Geisinger Clinic
Obesity
Study To Determine The Effects And Safety Of A Weight Loss Compound On Overweight, Otherwise Healthy, Volunteers
The purpose of this study is to determine whether CP-866,087 is effective in the weight loss of overweight patients.
- Trial name
- NCT00479492
- Testing
- CP-866,087
- Where
- 4 sites in United States
- Volunteers
- 94 people
- Sponsor
- Pfizer
Obesity, Overweight
Obex, a Nutritional Supplement, in Overweight and Obese Spanish Women
The aim of the study is to evaluate the effects of a dietary supplement (Obex®) on anthropometric and physiological variables in Spanish women between 35 and 60 years who are overweight or obese.
- Trial name
- NCT01934036
- Testing
- Obex
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Catalysis SL
Obesity, Weight Loss
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
In the proposed study, we will be evaluating the effects of pylorus sparing antral myotomy alone, without concomitant endoscopic sleeve gastroplasty (ESG), on weight loss for subjects undergoing the procedure with a history of…
- Conditions
- Obesity, Weight Loss, Delayed Gastric Emptying Following Procedure, Obesity, Mild
- Trial name
- BEAM (NCT05713071)
- Testing
- Bariatric Endoscopic Antral Myotomy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital