Clinical trials: Weight Regain
the Management of Weight Regain After Gastric Bypass by Endoscopic Suturing
Assessment of the Overstich Technique for the Management of Weight Regain After Gastric Bypass.
Prospective multicenters randomized study to compare the efficiency and the socioeconomic impact of the endoscopic management (Overstitch technique) of weight regain after gastric bypass surgery to non invasive treatment
- Trial name
- APOLLO (NCT02048033)
- Testing
- Regular endoscopy + endogastric suturing, Regular endoscopy
- Where
- 7 sites in France
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Obesity, Weight Loss
Empowered With Movement to Prevent Obesity and Weight Regain
This study will help determine the appropriate type, amount and intensity of physical activity most beneficial for preventing weight regain after weight loss in older adults.
- Conditions
- Obesity, Weight Loss, Sedentary Lifestyle
- Trial name
- EMPOWER (NCT02923674)
- Testing
- Weight loss, Exercise, Sitless
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- Wake Forest University Health Sciences
Obesity
Engaging Motivation for the Prevention of Weight Regain
The purpose of this study is to determine whether a 12 week Mindfulness-Based Weight Loss Maintenance (MBWLM) intervention is effective in maintaining recent loss of 10% or more of initial body weight.
- Trial name
- EMPOWER (NCT01169428)
- Testing
- Mindfulness Based Weight Loss Maintenance (MBWLM), Behavioral: Standard Behavioral Weight-Loss Maintenence
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Duke University
Obesity
Adipogenic Capacity as a Mediator of Weight Gain
To demonstrate differences in response of subjects with a high, low or medium predisposition for weight regain after weight reduction in terms of: body composition; energy expenditure; physical activity; and adipogenic capacity.
- Trial name
- NCT01015508
- Testing
- Very Low Energy Diet (VLED), Weight maintenance
- Where
- Netherlands
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Obesity, Morbid
Procedure for Duodenal-Ileal Diversion for Patients With Weight Regain Following Sleeve Gastrectomy
Study will monitor weight loss and metabolic indicators for subjects in single-center, single arm trial.
- Trial name
- SNAP-PS (NCT05049824)
- Testing
- Self Forming Magnetic (SFM) Anastomosis System
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- GI Windows, Inc.
Weight Loss, Weight Gain
Role Of Metabolic Adaptation In Weight Regain
In a previous study (NCT04081337), 55 participants with obesity participated on a 18-week lifestyle intervention to reduce their body weight, targeting 10% body weight loss.
- Conditions
- Weight Loss, Weight Gain, Obesity
- Trial name
- EXPEND-FU (NCT05766358)
- Testing
- Intensive lifestyle change therapy, Tirzepatide
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Pennington Biomedical Research Center
Abdominal Fat, Body Weight
Effects of Whole Grain on Weight Maintenance
Epidemiological studies suggest that whole grain consumption affects measures of obesity including BMI, body fat tissue, and body weight.
- Trial name
- NCT01239147
- Testing
- Diet rich in whole grain, Refined grain
- Where
- France
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Cereal Partners Worldwide
Obesity
Pharmacotherapy in Conjunction With Lifestyle Counseling for Management of Weight Regain After Bariatric Surgery
This is a randomized controlled trial employing a Sequential Multiple Assignment Randomized Trial (SMART) design to test whether pharmacotherapy, in conjunction with lifestyle counseling, can reverse weight regain after bariatric…
- Trial name
- PROJECT-BARI (NCT05975580)
- Testing
- Topiramate, Phentermine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Irvine
Anorexia Nervosa
Impact of Body Schema Distortion on Remission and Weight Regain in Anorexia Nervosa
Anorexia nervosa is a predominantly female eating disorder that most often appears in adolescence. The latter leads to strict and voluntary food deprivation for several months or even years.
- Trial name
- SCAM (NCT05682417)
- Testing
- Body Map Assessment Tool: MOVE Tool, PAQ questionnaire, F-DFlex questionnaire
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Hospices Civils de Lyon
Obesity
Endoscopic Stomach and Pouch Reduction in Patients With Weight Regain Following Roux-En-Y Bypass Surgery
The Roux-En-Y gastric bypass procedure is the most commonly performed bariatric procedure in the United States. Despite initial weight loss, some patients experience weight regain that may be related to an increase in the size of…
- Trial name
- NCT00411489
- Testing
- endolumenal surgery
- Where
- 4 sites in United States
- Sponsor
- USGI Medical
Morbid Obesity
Banded Versus Non-banded Roux-en-Y Gastric Bypass
This is a prospective randomized Study comparing Weight loss, Esophageal Motility and Reflux in lap. Gastric Bypass vs. lap. Banded-Gastric Bypass using the A.M.I. Soft Gastric Bypass Band (B-Band.
- Trial name
- NCT01078181
- Testing
- gastric bypass
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Obesity
Roux-en-Y Gastric Bypass and Weight Regain
This study compares eating behaviors, meal size, and the size of the gastric pouch and connection between the gastric pouch and small intestine in patients who had gastric bypass surgery two or more years ago and regained weight…
- Trial name
- NCT02302898
- Testing
- Eating Behavior Evaluation, Measurement of Functional gastric volume, Measurement of gastric pouch and GJ size
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Washington University School of Medicine
Obesity, Morbid, Bariatric Surgery Candidate
Use of Mysimba in Patients With Weight Regain After Bariatric Surgery
Although bariatric surgery is currently the most effective treatment for morbid obesity, weight regain occurs in 16-37% of the patients (1). Weight regain is not regularly treated with antiobesity medications (AOMs).
- Conditions
- Obesity, Morbid, Bariatric Surgery Candidate, Medication Persistence
- Trial name
- NCT04902625
- Testing
- Naltrexone-Bupropion Combination
- Where
- Netherlands
- Volunteers
- 116 people
- Sponsor
- Zuyderland Medisch Centrum
Weight Regain, Weight Loss
Randomized Study on Transoral Outlet Reduction and Lifestyle Changes for Weight Regain After Gastric Bypass
The goal of this clinical trial is to evaluate weight loss with TORe and moderate to intensive lifestyle modification versus moderate to intensive lifestyle modification alone in subjects who have regained weight following a…
- Trial name
- REIGNITE (NCT07015424)
- Testing
- TORe with OverStitch, Intensive lifestyle modification
- Where
- 12 sites in United States
- Volunteers
- 108 people
- Sponsor
- Boston Scientific Corporation
Obesity
Investigating Physiological Adaptations to Weight Loss
The purpose of this study is to examine the effect of diet-induced weight loss on the levels of circulating nutrients and hormones which are involved in feelings of hunger and satiety.
- Trial name
- NCT00870259
- Testing
- Optifast VLCD
- Where
- Australia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Obesity
A Trial Evaluating the Effectiveness of Contrave in Patients Who Have Weight Recidivism Following Bariatric Surgery
Contrave (naltrexone HCl and bupropion HCl) extended-release tablet is an approved drug and indicated to be used with a low calorie diet and increased physical activity for chronic weight management in obese adults (BMI 30 Kg/m2…
- Trial name
- COR-WR (NCT04587843)
- Testing
- Contrave 8Mg-90Mg Extended-Release Tablet
- Where
- 4 sites in Canada
- Volunteers
- 18 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Obesity
Gut Microbiota Post Roux-en-Y Gastric Bypass Surgery
The purpose of this study is to investigate mechanisms responsible for weight change in patients who have undergone weight loss surgery.
- Trial name
- NCT02654496
- Testing
- Meal challenge
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- North Dakota State University