Clinical trials: Well Aging
Healthy Aging, Alzheimer's Disease
The Feasibility, Safety and Tolerability of VR-based Audiovisual Stimulation
This single-session, within-subject, sham-controlled early feasibility study evaluated the safety, tolerability, and feasibility of delivering 40 Hz audiovisual (gamma sensory) stimulation through a virtual reality (VR) headset…
- Conditions
- Healthy Aging, Alzheimer's Disease, Mild Cognitive Impairment
- Trial name
- CFS (NCT06234930)
- Testing
- Audiovisual stimulation VR system
- Where
- 2 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Clarity Health Technologies, Inc
Joint Discomfort, Wellbeing
Assessing the Potential for Improved Joint Health and Wellbeing by Providing a Whole Salmon Oil With Undenatured Type II Collagen Compared to Type II Collagen Alone
This study evaluates the combination of NT-II® salmon undenatured type II collagen with OmeGo® salmon oil in adults who regularly experience knee discomfort.
- Conditions
- Joint Discomfort, Wellbeing, Quality of Life
- Trial name
- NCT07875101
- Testing
- Undenatured collagen, Whole salmon oil
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hofseth Biocare ASA
Healthy Aging, Muscle Function
The Effect of Urolithin A (Mitopure®) Supplementation on Muscle Strength in Healthy Middle-Aged Adults
This is a randomised, double-blind, placebo-controlled, parallel study to assess the effects of Urolithin A (Mitopure®) supplementation on muscle strength and performance in healthy middle-aged adults.
- Trial name
- ATLAS 2 (NCT07231783)
- Testing
- Mitopure® 500mg, Mitopure® 1000mg
- Where
- Ireland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Healthy
Behavioral and Physiological Effects of Visual Training
The primary objective of this study is to evaluate the learnability of a 3 week, 40 minutes per day, 5 day per week, computer-based visual training exercise by healthy mature individuals undergoing normal aging.
- Trial name
- NCT00526942
- Testing
- SAAGE-designed, visual memory-based cognitive training
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Intervention Group, Control Group
Innovative Web-based Service Platform Called Adult Wellbeing CheckUp (AWC) to Assess Older Adults Wellbeing, Obtain Evidence-based Recommendations, and Receive Support to Take Action.
The goal of this clinical trial is to learn whether a web-based program called the Adult Wellbeing CheckUp (AWC) can help older adults improve their wellbeing and take actions to support healthy aging.
- Trial name
- NCT07489170
- Testing
- Adult Wellbeing CheckUp (AWC), General Healthy Aging Information
- Where
- United States
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- BellAge Inc.
Healthy Aging
A Pharmacokinetic Study of a Novel Nutritional Product on Healthy Men and Women
This study is a randomized, double-blind, placebo-controlled study of N=16 apparently healthy men and women. The purpose of this study is to examine the bioavailability of a health and wellness supplement.
- Trial name
- NCT06316700
- Testing
- Nutritional supplement
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Aging
The Bioavailability of Compounded and Generic Rapamycin in Normative Aging Individuals
This study collected real-world evidence to better understand and define the relative bioavailability ratio between compounded rapamycin and generic rapamycin, with a specific focus on relative efficacy in increasing rapamycin…
- Trial name
- NCT06550271
- Testing
- Rapamycin
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- AgelessRx
Hearing Loss
Evaluation of the Benefits for Overall Health Following Cochlear Implant Treatment in the Elderly Population
The purpose of this study is to show that cochlear implant treatment improves the overall health related quality of life and general well-being in elderly individuals.
- Trial name
- NCT03072862
- Testing
- Commercial Nucleus Cochlear Implant Systems
- Where
- 8 sites in France, Israel and 2 more
- Volunteers
- 100 people
- Sponsor
- Cochlear
Skin Aging of Face and Hands, Cicatrix
A Clinical Study Testing How Well the Medical Device HTIC (a Type of Animal-derived Collagen) Works in Treating Skin Problems, Such as Scars, Loss of Firmness, and Volume in Certain Areas of the Face and Body
This clinical trial aims to evaluate the efficacy of the experimental medical device HTIC, which contains Type I collagen of animal origin, in treating skin defects such as scars, loss of tone, and volume in certain areas of the…
- Conditions
- Skin Aging of Face and Hands, Cicatrix, Scars, Atrophic Scar
- Trial name
- NCT07153393
- Testing
- Type I Bovine Collagen (HTIC)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Centro Studi Dermatologici S.r.l.
Cognitive Decline, Cognitive Function
A Clinical Trial to Investigate the Efficacy of a Supplement to Improve and Maintain Cognitive Function and Memory
This study will evaluate the efficacy of 1MD Nutrition's MindMD supplement in improving and maintaining cognitive function and memory.
- Trial name
- NCT06523218
- Testing
- MindMD Supplement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Scale Media Inc
Systemic Inflammation (hsCRP), Healthy Aging
Evaluation of AppleX™ Apple Extract on Anti-Inflammatory and Healthy Aging Effects
The goal of this clinical trial is to learn if AppleX™ Apple Extract can help lower systemic inflammation in adults aged 45-70 with signs of low-grade inflammation.
- Conditions
- Systemic Inflammation (hsCRP), Healthy Aging, Vitality, Healthy Adult Participants
- Trial name
- NCT07678346
- Testing
- Apple Extract
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Nutraland USA, Inc.
Aging, Healthy Aging
Biological Effects in Consumers of Resveratrol-enriched Wine
The objective of this clinical trial is to compare the health conditions of the participating population before and after an intervention with Resveratrol enriched wine. The main questions it aims to answer are: 1.
- Conditions
- Aging, Healthy Aging, Sarcopenia, Obesity
- Trial name
- NCT05981053
- Testing
- Wine enriched with Resveratrol
- Where
- Argentina
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- PINER Pastor Manfredi Winery
Healthy Adult Females
Clinical Study to Evaluate the Anti-aging Efficacy and Skin Radiance-enhancing Effect of Dermial®.
The present clinical study has been designed to evaluate the efficacy and safety of Dermial® at a daily dose of 60 mg on skin brightness, hydration, luminosity and other signs of facial skin aging in healthy women aged 35 to 65…
- Trial name
- Dermiglow (NCT07790237)
- Testing
- DERMIAL
- Where
- Spain
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Aging
aKLmRNA-mediated Protein Replacement Therapy
This is a Phase 1b randomized, double-blind, placebo-controlled study to assess the safety and tolerability of a proprietary aKLmRNA formulated in lipid nanoparticles. Approximately 21 subjects will be enrolled.
- Trial name
- NCT07544420
- Testing
- aKLmRNA (AKL003)
- Where
- Honduras
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Klothea Bio Inc
Longevity, GLP-1
Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation
The goal of this randomized, controlled trial is to evaluate the effectiveness of alternative therapies (metformin alone, with rapamycin, and with low-dose naltrexone) in maintaining weight loss in patients weaning off GLP-1…
- Conditions
- Longevity, GLP-1, Geroscience, Aging
- Trial name
- NCT07092618
- Testing
- Metformin, Rapamycin, Naltrexone
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- AgelessRx
Anti Aging
Effects of a Proprietary Blend of Herbal Extract Supplement on Cellular Detoxification, Inflammation, and Cumulative Cognitive Index as Well as Gene Expression in Middle-Aged Adult Women
Determine the effects of 8 week Investigational Supplement on cellular detoxification and gene expression profiles
- Trial name
- Pharmanex (NCT01598272)
- Testing
- Vitality product AM + Vitality product PM
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Pharmanex
Menopause, Perimenopausal Disorder
Virtual perI-/Menopause Registry of AusTrALia
13 million (50.7%) Australians are born with ovaries, 14% (~3 million) are currently aged 40-59 yrs, \& all such who live to midlife will experience menopause, defined as >12 months without a period.
- Conditions
- Menopause, Perimenopausal Disorder, Postmenopausal Symptoms, Health Knowledge, Attitudes, Practice
- Trial name
- VITAL (NCT06487130)
- Testing
- N/A Observational Registry
- Where
- Australia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bespoke Clinical Research
Healthy Ageing, Protein Supplementation
The Effects of PeptiStrong and Whey on Muscle Function In Older Adults
Examining the effects of PeptiStrong and protein on muscle function in older adults
- Conditions
- Healthy Ageing, Protein Supplementation, Muscle Health, Muscle Function
- Trial name
- NCT07528469
- Testing
- PeptiStrong + whey protein, Whey protein
- Where
- United Kingdom
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Nuritas Ltd
Gastrointestinal Microbiome, Nutrition, Healthy
The Effects of a Novel Nutritional Product on Nutrient Status and Digestive Health
This study is a randomized, double-blind, placebo-controlled study of N=30 apparently healthy men and women. This is an exploratory study to assess the effect of a novel dietary supplement on blood markers of nutrient status and…
- Conditions
- Gastrointestinal Microbiome, Nutrition, Healthy, Healthy Aging
- Trial name
- NCT06181214
- Testing
- AG1 - Nutritional Supplement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Athletic Greens International
Female, Healthy Aging
The Impact of Probiotics on Well-being in Women
An exploratory study to determine whether daily supplementation with a probiotic product impacts the overall well-being of women aged between 45 - 65
- Trial name
- ProWOME (NCT06507111)
- Testing
- Lab4P
- Where
- Bulgaria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cultech Ltd