Clinical trials: Well Aging, open to volunteers
Chronic Pain, Physical Activity
Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline
The investigators aim to conduct a randomized controlled trial to compare two symptom-management programs for Black older adults with early cognitive decline (self-reported confirmed by testing) and chronic pain.
- Conditions
- Chronic Pain, Physical Activity, Older Adults, Mild Cognitive Impairment
- Trial name
- HABIT (NCT06246929)
- Testing
- MBCT+w, ALED
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Massachusetts General Hospital
Aging, Behavior
NHRI Intelligent Voice Interactive Platform for High-Quality Community Living Among Older Adults
The goal of this clinical trial is to evaluate the impact of an integrated smart voice platform on quality of life and local healthy aging among community-dwelling older adults in both urban and rural areas.
- Trial name
- NCT07855874
- Testing
- NHRI Smart Voice Interaction Platform
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Mild Neurocognitive Disorder, Healthy Aging
tFUS for Memory in mNCD and Healthy Adults
Dementia is an ongoing and growing public health crisis in the US and worldwide. The purpose of this study is to examine a form of noninvasive brain stimulation called transcranial focused ultrasound (tFUS) to the hippocampus…
- Trial name
- NCT06718140
- Testing
- Transcranial Focused Ultrasound
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Frailty, Age-Related Macular Degeneration
Visual Frailty in Ageing
The goal of this observational study is to define visual frailty and refine monitoring for an ageing population. It involves piloting a visual frailty assessment tool in a cohort of patients aged 60 and above with a known…
- Conditions
- Frailty, Age-Related Macular Degeneration, Functional Status, Mental Health
- Trial name
- VFiA (NCT06604104)
- Where
- 2 sites in United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Diabetes Mellitus Type 1, Healthy Ageing
FinnDiane LifeOne Study - Impact of Ageing on People With Type 1 Diabetes
Healthy aging refers to functional ability that enables well-being in older individuals. The focus thus shifts from chronological age to functional capacity and the individual's own experience of well-being.
- Trial name
- LifeOne (NCT07289204)
- Where
- Finland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Aging, Alzheimer Disease
Exercise to Improve Brain Health in Older African Americans
The goal of this clinical trial is to test the effects of different types of exercise on brain health and Alzheimer's risk in older African Americans.
- Conditions
- Aging, Alzheimer Disease, Healthy Aging, Cognitive Change
- Trial name
- NCT05597124
- Testing
- Cardio-Dance Fitness, Strength, Flexibility & Balance
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Dehydrated, Water-Electrolyte Imbalance, Malnutrition, Dehydration (Physiology)
Effects of Increased Water Intake on Hormonal Response, Hydration Status, and Physical Function in Low-drinking Older Adults
DrinkAge is a randomized controlled trial investigating whether increasing daily water intake can improve hydration and health-related outcomes in adults aged 60 years or older who habitually drink relatively little water.
- Trial name
- DrinkAge (NCT07892742)
- Testing
- Water
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Polytechnic University of Santarém
Ageing
Effectiveness of the WHO ICOPE (Integrated Care for Older People) Program in Preventing Age-related Functional Decline (ICOPE Trial.Fr)
The World Health Organization (WHO) has designed an integrated care program (ICOPE) aimed at maintaining the functions of elderly people to preserve their autonomy.
- Trial name
- ICOPE Fr (NCT06676839)
- Testing
- the complete ICOPE program
- Where
- 6 sites in France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Toulouse
Lewy Body Disease, Healthy Aging
Language and Lewy Body Diseases: Sentence Comprehension Problems and Modifying Noninvasive Brain Stimulation Treatment
Lewy body diseases (LBDs) represents a group of neurodegenerative disorders characterized by the abnormal accumulation of aggregates of α-synuclein protein leading to the formation of Lewy bodies (LB) and Lewy neurites resulting…
- Trial name
- LANG-LBD (NCT05847985)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Digital Health Literacy, Healthy Aging
Effectiveness of Intensive Tutoring vs. Flexible Self-Learning on Digital Health Literacy and Self-Efficacy for "My Health Bank" App Use Among Adults Over 50
The purpose of this study is to evaluate the effectiveness of two different educational models in improving the use of the "My Health Bank" App (a Personal Health Record system in Taiwan) among adults aged 50 and older.
- Trial name
- NCT07515495
- Testing
- AI-Collaborative eHealth Education
- Where
- 2 sites in Taiwan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Atherosclerosis Cardiovascular Disease, Obesity
Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.
This study aims to investigate how moderate wine consumption influences circulating extracellular vesicles (EVs) in healthy adults.
- Conditions
- Atherosclerosis Cardiovascular Disease, Obesity, Metabolic Syndrome, Metabolic Disorders
- Trial name
- (WINEVOME) (NCT07361887)
- Testing
- White Wine, Red Wine, Water
- Where
- Spain
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Seville
Aging, Visual Perception
RePer-AGE: Reorganization of Visuo-cognitive Functions Based on Peripheral Vision With Aging
The RePer-AGE study investigates how central and peripheral vision contribute to visual recognition and how these mechanisms change with normal aging.
- Conditions
- Aging, Visual Perception, Cognition
- Trial name
- RePer-AGE (NCT07727369)
- Testing
- Psychophysical visual recognition tasks, Ophthalmological assessment, Functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Healthy Adult Participants, Gut Microbiomes
DORA - A Study Using Digital Health Tools/Platform to Explore the Impact of the Consumption of Senior Milk Powder Containing Synbiotics on the Gut micRobiome in Healthy Aging Individuals
The DORA study is a single-arm, open-label, interventional exploratory study designed to evaluate the impact of a synbiotic-containing senior milk powder on the gut microbiome and selected biological, physiological, and digital…
- Conditions
- Healthy Adult Participants, Gut Microbiomes, AI
- Trial name
- DORA (NCT07575529)
- Testing
- Synbiotic Nutritional Product
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Danone Asia Pacific Holdings Pte, Ltd.
Healthy Aging, Cognition
Effects of Cannabidiol on Memory and Attention in Adults Aged 60-70: A Pilot Study
This pilot study aims to investigate the effects of a single oral dose of cannabidiol (CBD) on memory and attention in healthy adults aged 60 to 70 years.
- Trial name
- CBD-MAP (NCT07910292)
- Testing
- Cannabidiol (CBD)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Healthy Aging, Skin Aging
NVTIA® Ergothioneine for Healthy Aging and Skin Health
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of NVTIA® Ergothioneine, a branded ergothioneine ingredient, on healthy aging biomarkers and skin health in healthy…
- Conditions
- Healthy Aging, Skin Aging, Oxidative Stress
- Trial name
- NCT07750002
- Testing
- NVTIA® Ergothioneine
- Where
- Bangladesh
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EUROPEAN LIFE SCIENCE RESEARCH ASSOCIATION
Frailty, Older Adults
+AGIL Barcelona: Integrated Care for Community-Dwelling Frail Older Adults
The goal of this clinical trial is to evaluate the effectiveness of the +AGIL Barcelona program in helping older adults improve their physical abilities and delay disability.
- Conditions
- Frailty, Older Adults, Healthy Aging
- Trial name
- +AGIL (NCT06836167)
- Testing
- exercise promotion, review medication, promoting healthy aging
- Where
- 3 sites in Spain
- Volunteers
- 396 people
- Sponsor
- Parc Sanitari Pere Virgili
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Mild Cognitive Impairment, Cognitive Decline
Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging
The study will examine whether 5mg melatonin (over the counter, OTC) over a 9-month period improves Alzheimer's disease (AD) biomarkers and cognitive function in two groups of individuals: those with mild cognitive impairment…
- Conditions
- Mild Cognitive Impairment, Cognitive Decline, Healthy Aging
- Trial name
- NCT03954899
- Testing
- melatonin
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Natalie Denburg
Mindfulness, Healthy Aging
Effectiveness of a Mindfulness and Digital Technology Program for Healthy Aging (MMP-DTLA)
This study aims to evaluate the effectiveness of a mindfulness program integrated with digital technology-assisted learning on healthy aging among community-dwelling older adults.
- Trial name
- MMP-DTLA (NCT07025655)
- Testing
- Multifaceted Mindfulness Program
- Volunteers
- 100 people
- Sponsor
- Chang Gung University of Science and Technology