Clinical trials: Well-being
Smoking Cessation, Alcohol-Related Disorders
Effectiveness of Bupropion for Smokers Recovering From Alcohol Dependence
Smoking is often a problem for alcohol dependent individuals. Many people who seek treatment for alcohol dependence are unable to quit smoking.
- Trial name
- NCT00304707
- Testing
- Bupropion
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Gratitude + No Expectations, Gratitude + Expectations
The Effects of Manipulating Expectations in a Gratitude Intervention
Gratitude - an emotion felt when an individual receives something beneficial from other people or entities - has been shown to positively affect well-being.
- Conditions
- Gratitude + No Expectations, Gratitude + Expectations, Events Control
- Trial name
- NCT03784001
- Testing
- Gratitude + No Expectations Intervention, Gratitude + Expectations Intervention, Events Control Intervention
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Intervention
A Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
This is a pilot study to evaluate the feasibility of a mobile health exercise intervention (GO-EXCAP Mobile App) over 7 weeks in 25 patients with myeloid neoplasms receiving hypomethylating agents.
- Trial name
- GO-EXCAP (NCT04035499)
- Testing
- GO-EXCAP Mobile App
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Adolescent, Bullying
Online Bullying Bystander Intervention for Middle Schools Phase II
School interventions to reduce bullying can be effective but also require substantial time and resources. Online technologies have the potential to deliver effective bullying interventions to a large number of middle school…
- Conditions
- Adolescent, Bullying, Technology, Mental Health
- Trial name
- STACII (NCT05572398)
- Testing
- STAC-T
- Where
- 2 sites in United States
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Smoking Cessation, Marijuana Use
Project CheckUP: A Brief Behavioral Intervention for Quitline Callers Who Use Marijuana (MJ) and Tobacco
Smoking cigarettes remains the number one preventable cause of death and disease in the US. Smokers who call tobacco quitlines and use marijuana struggle to quit tobacco due to the interactive effects of nicotine and marijuana.
- Trial name
- NCT04737772
- Testing
- Behavioral: Quitline treatment as usual, QL Marijuana Check-Up intervention (QL-MJCU)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Consumer Wellness Solutions
HIV
Mental Health and Medication Adherence Among MSM in South Africa
The goal of this behavioral study is to improve psychological well-being and optimization of HIV prevention and care outcomes for Men who have sex with men (MSM) in South Africa.
- Trial name
- NCT06880172
- Testing
- WeCare
- Where
- South Africa
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Schizophrenia, Stress Disorders, Post-Traumatic
Optimizing Cognitive Remediation
Veterans with mental illness face challenges with community reintegration, including achieving vocational success, attaining their educational goals and going back to school, and maintaining a high quality of life.
- Conditions
- Schizophrenia, Stress Disorders, Post-Traumatic, Generalized Anxiety Disorder, Mood Disorders
- Trial name
- NCT04395157
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- VA Office of Research and Development
HIV/AIDS, Health Behaviors
Expanding HIV Testing Among Uganda Adults Who Utilize Traditional Healers
HIV antiretroviral therapy has the potential to dramatically decrease HIV transmission worldwide1; yet, a barrier to ending the AIDS epidemic in low-resource settings is the fact that healthcare is largely provided by traditional…
- Trial name
- NCT03718871
- Testing
- HIV testing at traditional healer practices
- Where
- Uganda
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Mental Health Wellness 1, Burnout, Professional
ABC Mental Health: A Behavioral Study of K-12 Teachers and School Staff
This study looks at school employees' mental health, well-being, and effectiveness before and after completing a professional development workshop.
- Conditions
- Mental Health Wellness 1, Burnout, Professional, Self Efficacy
- Trial name
- NCT05574764
- Testing
- Cultivating Awareness and Resilience in Education (CARE)
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Duke University
Kidney Diseases, Cardiometabolic Risk Factors
Feasibility Trial of a Stakeholder-enhanced Lay-navigator-delivered Intervention (ImPart-Multi)
The purpose is to explore the feasibility and acceptability of participation in a decision-support training program led by lay navigators.
- Trial name
- ImPart-Multi (NCT06067009)
- Testing
- ImPart-Multi - IMproving the decisional PARTnership of Chronic Kidney Disease Dyads with concurrent metabolic disease
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus
Blood Glucose Monitoring in Electronic Health Records
This multi-site randomized tral aims to test methods of increasing adoption and integration of blood glucose monitoring into electronic medical records, and to measure the impact of wide-scale adoption on health status of…
- Trial name
- NCT03542487
- Testing
- Practice Orientation, Standard Reminder, Gift Card Reminder
- Where
- United States
- Volunteers
- 7,052 people, healthy volunteers welcome
- Sponsor
- Inova Health Care Services
Veteran Reintegration
Health Coaching: A Pilot Trial Among Reintegrating Veterans
Health coaches help people focus on goals, identify strengths and values, and work towards building the life they wish to live. Health coaching may be especially helpful for people navigating a life transition, such as Veterans…
- Trial name
- NCT05199467
- Testing
- Health Coaching, VA Benefits Information
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Hypercholesterolemia, Hydroxy-methylglutaryl-coenzyme A (HMG Co-A) Reductase Inhibitors Adverse Reaction
Genetically Guided Statin Therapy
The purpose of this study is to examine if using genetics can improve statin adherence in patients who should be taking statins but are not because of prior side effects.
- Trial name
- NCT01894230
- Testing
- SLCO1B1*5 allele testing, results reported at randomization, SLCO1B1*5 allele testing, results reported at end of study, Genetic testing for SLCO1B1*5 allele
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Duke University
Hospitalization, Infection
Project PROTECT: Protecting Nursing Homes From Infections and Hospitalization
This is a cluster-randomized trial of nursing homes to assess whether decolonization with routine chlorhexidine bathing and periodic use of nasal antiseptics can reduce hospitalizations associated with infections, antibiotic…
- Trial name
- PROTECT (NCT03118232)
- Testing
- Chlorhexidine gluconate (CHG), Iodophor (10% povidone-iodine)
- Where
- 28 sites in United States
- Volunteers
- 13,952 people
- Sponsor
- University of California, Irvine
Hepatitis C, Chronic
Role of Pegylated Interferon in Combination With DAAs to Cure Hepatitis C As Soon As Possible - Hepatitis C [ASAP-C]
The primary objective of this pilot trial is to compare the efficacy, measured as sustained virologic response (SVR) at least 12 weeks after completion of therapy, across three study regimens/delivery modalities: Arm 1 - 4 weeks…
- Trial name
- NCT03480932
- Testing
- Sofosbuvir, Daclatasvir, Pegylated Interferon alfa-2a
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Schizoaffective Disorder, Schizophrenia
Smoking Cessation for Veterans With Severe and Persistent Mental Illness
The investigators have developed an intervention called Behavioral Treatment of Smoking Cessation in SPMI (BTSCS), an innovative intervention that supplements pharmacotherapy and education with contingency management and a…
- Conditions
- Schizoaffective Disorder, Schizophrenia, Affective Psychosis, Bipolar, Affective Disorders, Psychotic
- Trial name
- NCT00960375
- Testing
- BTSCS, StSST
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- US Department of Veterans Affairs
Nondaily Smoking
A Proof-of-concept RCT of Version 3.0 of the Smoking Cessation Smartphone App "Smiling Instead of Smoking" (SiS)
This is the third study in a series of 3 studies to develop a smartphone app to support nondaily smokers in quitting smoking, as funded by the American Cancer Society grant #RSG CPPB - 130323 (project dates: 07/01/2017 …
- Trial name
- NCT04672239
- Testing
- Smartphone app "Smiling instead of Smoking" (SiS) Version 3, Smartphone app "QuitGuide" (QG), Brochure "Clearing the Air" (CTA)
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Prescription Opioid Misuse
Reducing High School Athletes' Prescription Opioids Misuse and Diversion Through the Student Athlete Wellness Portal
The goal of this study is to prevent prescription opioid misuse among high school athletes by developing, demonstrating the feasibility, and evaluating the outcomes of an innovative digital intervention.
- Trial name
- NCT05209191
- Testing
- Student Athlete Wellness Portal
- Where
- 5 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Real Prevention, LLC
Transgender Persons, Sexual Health
The Experiences of Erotic and Sexual Risk of Transgender Men: Exploratory Research Design
Transgender male (TM) is the minority and difficult to reach-up group. Therefore, there is a lack of research on private issues involving TM, such as sex, eroticism, and sexual risk behavior.
- Trial name
- NCT05187442
- Testing
- questionnaire, interview
- Where
- Taiwan
- Volunteers
- 350 people
- Sponsor
- National Taiwan University
Sedentary Lifestyle
Exercise Effects on Brain Health and Learning From Minutes to Months
Given the accelerating growth of older adults worldwide and the decline in cognitive function with aging, therapeutics that remediate age-related cognitive decline are needed more than ever.
- Trial name
- EXTEND (NCT03114150)
- Testing
- Cardiorespiratory fitness training, Functional fitness training
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Michelle W. Voss