Clinical trials: Well-being
Brain Aging in Mexican Americans
Health & Aging Brain Study: Health Disparities TAU Project
By doing this study we are trying to learn more about brain aging in Mexican Americans. Participants will be asked to complete a screening visit to determine if it is safe to undergo a PET scan.
- Trial name
- NCT04324541
- Testing
- PET scan of the brain with Flortaucipir
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Sid E. O'Bryant
Intestinal Microbiota and Barrier Function
Use of a Novel Synbiotic to Change Human Gut Bacteria and Improve Health in Obese Adults
This study evaluates the effect of a dietary supplement to improve gut health. The participants will take one of six dietary treatments for three weeks, and the gut bacteria and the gut intestinal barrier will be assessed to…
- Trial name
- NCT02355210
- Testing
- Bifidobacteria adolescentis BD1, Bifidobacteria animalis subsp. lactis BB-12, Bifidobacteria adolescentis BD1 and galactooligosaccharide
- Where
- United States
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Genital Warts, Human Papilloma Virus
Typing of Human Papilloma Virus (HPV) From Female Genital Warts
This is a longitudinal observational study of women presenting to Groote Schuur Hospital with genital warts. The study will evaluate the socio-demographic characteristics of the women using a structured questionnaire.
- Trial name
- NCT01192282
- Testing
- Medical / Surgical Treatment
- Where
- South Africa
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
PreDiabetes, Dysbiosis
Assessing Gut Microbiota Mediated Health Outcomes of Whole Wheat and Its Major Bioactive Components
This study will investigate the gut microbiota-mediated effects of whole wheat consumption on human health in adults with pre-diabetes.
- Conditions
- PreDiabetes, Dysbiosis, Endotoxemia, Inflammation
- Trial name
- NCT05318183
- Testing
- Whole Wheat Bread, White Bread (control)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Ohio State University
Childhood Obesity
Impact of Body Weight on the Immediate Health of the Pediatric Population
Objective: Obesity amongst children is a public health issue in the United States and is rising at an alarming rate. The purpose of this study is to determine if there is any correlation between At Risk body weight (overweight…
- Trial name
- NCT00267631
- Where
- United States
- Volunteers
- 5,392 people, healthy volunteers welcome
- Sponsor
- Antonios Likourezos
Sepsis
Pharmacokinetic and Pharmacodynamic Evaluation of Doripenem in Critically Ill Trauma Patients
The study hypothesis is to measure how the drug doripenem is cleared from the body of critically ill trauma patients. The investigators will measure blood drug concentrations and calculate how much the drug distributes in the…
- Trial name
- NCT01027897
- Testing
- Doripenem
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Delirium
Supporting the Health of Adults Undergoing Orthopedic Surgery During the Recovery Period
Delirium (acute confusion) is a highly prevalent condition among hospitalized elders with substantial morbidity within the hospital and beyond.
- Trial name
- SHARP (NCT00586196)
- Testing
- donepezil
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Beth Israel Deaconess Medical Center
Diabetes Mellitus
SEGUDIAB Study: Evaluation of Safety in the Diabetic Patients
The safety in the diabetic patient refer so much to the accuracy of the treatment and to the handling of the diabetic in security topics.
- Trial name
- SEGUDIAB (NCT01087541)
- Testing
- Educational program 6-hour standardized
- Where
- Spain
- Volunteers
- 6,830 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Hepatitis C
An Integrated Care Model for Improving Hepatitis C Virus Patient Outcomes
This is a prospective randomized controlled trial comparing two different clinic models for patients with hepatitis C. These patients commonly have mental health problems that are barriers to receiving HCV treatment.
- Trial name
- HCV (NCT00722423)
- Testing
- Integrated care model, Usual Care Model
- Where
- 3 sites in United States
- Volunteers
- 364 people
- Sponsor
- US Department of Veterans Affairs
Quitting Smoking
Financial Incentives for Smoking Cessation Treatment Engagement
This study is being done to see if financial incentives increase the rate at which smokers engage in cessation treatment. A total of 540 participants will be enrolled by invitation from 6 primary care clinics of the participating…
- Trial name
- NCT04601870
- Testing
- No Financial Incentive, Financial Incentive (100 dollars), Financial Incentive (50 dollars)
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Homelessness, Mental Health Conditions
ASPIRE Cognitive Enhancement Study
Cognitive impairments are present in up to 80% of homeless individuals, and may contribute to homelessness in Operation Enduring Freedom / Operation Iraqi Freedom / Operation New Dawn (OEF/OIF/OND) Veterans.
- Trial name
- ACES (NCT02657954)
- Testing
- CCT, HCE
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- VA Office of Research and Development
Schizophrenia, Schizo Affective Disorder
Examining a Digital Health Approach for Advancing Schizophrenia Illness Self-management and Provider Engagement
The effective treatment of schizophrenia is very challenging due to a number of factors. These include issues such as poor engagement with treatment plans and care providers, limited contacts with providers due to under-resourced…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Psychotic Disorders
- Trial name
- NCT04602741
- Testing
- A4i Intervention
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- Centre for Addiction and Mental Health
Diabetes Mellitus, Asthma
Evaluation of VLER-Indiana Health Information Exchange Demonstration Project
Three out of four Veterans receive a portion of their care from non-VA providers. On April 9, 2009, President Barack Obama directed the Department of Veterans Affairs and the Department of Defense to create the Virtual Lifetime…
- Conditions
- Diabetes Mellitus, Asthma, Cardiovascular Diseases, Heart Failure
- Trial name
- VLER-IHIE (NCT01446705)
- Testing
- Active Health Information Exchange, Non-Active Health Information exchange
- Where
- United States
- Volunteers
- 57,073 people
- Sponsor
- VA Office of Research and Development
Behavior, Health, Child Obesity
Greenlight Plus Study: Approaches to Early Childhood Obesity Prevention
A randomized controlled trial enrolling 900 parent-infant dyads (English and Spanish speaking) comparing Greenlight (control), a behavioral intervention focusing on nutrition, physical activity, media use, and sleep as compared…
- Trial name
- NCT04042467
- Testing
- Greenlight Plus, Greenlight
- Where
- 6 sites in United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Tobacco Use Cessation, Tobacco Use Disorder
Text Messaging for Supporting Quit Attempts
This study is a preliminary research aimed to compare the feasibility and effectiveness of motivational interview (MI), Personalized text messages (TM) and usual care for outpatients, with focus on smoking cessation as the main…
- Trial name
- NCT02571244
- Testing
- Motivational Interview plus text message
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Juiz de Fora
Smoking Cessation
Pharmacist Intervention to Improve Smoking Cessation
The goal of this study is to assess the effectiveness of a remote pharmacist intervention to help smokers quit. The main questions it aims to answer are: Will smokers being screened for lung cancer with low-radiation-level chest…
- Trial name
- NCT06943287
- Testing
- Pharmacist Intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Iowa
Hepatitis C, Chronic
Real World Study: Genotype 1 Chronic Hepatitis C Virus Treatment and Evaluation of Real World SVR and PRO
This is a Phase IV, open-label, multi-center study to evaluate the real world sustained virological response rate, subject adherence, and subject reported outcomes during and after treatment of non-cirrhotic genotype 1 chronic…
- Trial name
- NCT02461745
- Testing
- ombitasvir, paritaprevir/r, dasabuvir + ribavirin, ombitasvir, paritaprevir/r, dasabuvir
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Kaiser Permanente
Chronic Pain
Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans
The overarching goal of this Pain Management Collaboratory Demonstration project is to test a new Whole Health paradigm for chronic pain care, emphasizing non-pharmacological pain self-management that is hypothesized to reduce…
- Trial name
- wHOPE (NCT04330365)
- Testing
- Whole Health Team (WHT) Intervention Arm, Primary Care Group Education (PC-GE) Intervention Arm, Usual Primary Care (UPC) Arm
- Where
- 6 sites in United States
- Volunteers
- 793 people, healthy volunteers welcome
- Sponsor
- San Francisco Veterans Affairs Medical Center
HIV Infections, Adolescent Development
Tailored Motivational Interviewing Implementation-Effectiveness Trial in Multidisciplinary Adolescent HIV Care Settings
The goal of this study is to test a multi-faceted Tailored Motivational Interviewing Implementation intervention (TMI), based on the Dynamic Adaptation Process (DAP) to scale up an Evidence-based Practice (EBP) in…
- Conditions
- HIV Infections, Adolescent Development, Care Eliciting Behavior, Patient Non-Compliance
- Trial name
- TMI (NCT03681912)
- Testing
- Competency: 12-Item Motivational Interviewing (MI) Coach Rating Scale (CRS), Randomized Guided Development of COPs with an internal facilitator after one year of implementation., CoP development without internal facilitation.
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Florida State University
Covid19
Leveraging CHWs to Improve COVID-19 Testing and Mitigation Among CJIs Accessing a Corrections-focused CBO
Given the likelihood of COVID-19 remaining an endemic disease among high-risk populations, establishing effective mitigation interventions will be critical to stemming community transmission.
- Trial name
- NCT04878328
- Testing
- Onsite Point-of-care
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Montefiore Medical Center
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