Clinical trials: Wheat Allergy, active
Non-celiac Wheat Sensitivity
Response to Different Wheat Genotypes in Not-celiac Wheat Sensitivity
Non-celiac gluten sensitivity (NCGS) is a condition where intestinal and extraintestinal symptoms are triggered by gluten ingestion in the absence of celiac disease and wheat allergy.
- Trial name
- NCT03024775
- Testing
- Wheat flour
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Familial Mediterranean Fever, Non-celiac Gluten Sensitivity
Can Gluten/Wheat or Other Foods be Responsible for FMF Attacks
Familial Mediterranean Fever (FMF) is a chronic hereditary autoinflammatory disease caused by mutations in the MEditerranean FeVer (MEFV) gene which codes for pyrin.
- Trial name
- NCT06338891
- Testing
- Main questionnaire, Secondary questionnaire
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Palermo
Non-celiac Gluten/Wheat Sensitivity
Urinary Gluten Immunogenic Peptides Detection in Non-celiac Gluten/Wheat Sensitivity
Non-celiac gluten/wheat sensitivity (NCGS/NCWS) is a syndrome characterized by both intestinal (irritable bowel syndrome [IBS]-like presentation) and extraintestinal symptoms (headache, migraine, "foggy mind", depression…
- Trial name
- NCT04219813
- Testing
- Urinary test
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Palermo
Food Allergy, Wheat Hypersensitivity
A Study to Evaluate the Safety, Efficacy, Pharmacokinetic and Pharmacodynamic Characteristics of LP-003 Injection in Participants With Wheat Allergy
This is a multicenter, randomized, open-label Phase II clinical study to evaluate the safety, efficacy, pharmacokinetic (PK), pharmacodynamic (PD) and immunogenicity profiles of LP-003 injection in participants with Wheat…
- Trial name
- NCT07816432
- Testing
- LP-003 Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Longbio Pharma (Suzhou) Co., Ltd.
Wheat Hypersensitivity, Immunotherapy
Comparison Efficacy Between Two Different Frequency of Maintenance Dose Oral Immunotherapy
Oral immunotherapy(OIT) is effective in desensitized food allergy. OIT protocols are not standardized, and a wide heterogeneity exists in the literature .
- Trial name
- NCT06035328
- Testing
- Wheat (Four times per week)
- Where
- Thailand
- Volunteers
- 64 people
- Sponsor
- Mahidol University
Inflammatory Back Pain
Inflammatory Back Pain and Gluten Free Diet
Articular involvement is the most frequent extra-intestinal manifestation of inflammatory bowel diseases (IBD). IBD-related spondyloarthropathy is mainly characterised by axial involvement (including inflammatory back pain…
- Trial name
- NCT03017716
- Testing
- Gluten free diet
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Palermo
Not-celiac Wheat Sensitivity
Bio-markers of Not-celiac Wheat Sensitivity
The aim of the investigators' study is to evaluate biochemical, immunological and histological characteristics of patients affected with the so-called "gluten (or wheat) sensitivity" who suffers from irritable bowel syndrome…
- Trial name
- NCT01762579
- Testing
- wheat flour, Xylose
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Palermo
Food Allergy
Short-Term Linvoseltamab Treatment on Top of Chronic Dupilumab Treatment for Adults With Severe Immunoglobulin E (IgE)-Mediated Food Allergy
This study is researching an experimental drug called linvoseltamab combined with another drug called dupilumab. The study is looking at patients who have severe IgE-mediated food allergy.
- Trial name
- NCT06369467
- Testing
- linvoseltamab, dupilumab
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- Regeneron Pharmaceuticals
Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity
Liver Steatosis and Fibrosis in Non-Celiac Wheat Sensitivity Patients: a Prospective Study
Hypothesizing an intestinal barrier impairment as a common pathophysiological substrate of both Non Celiac Wheat Sensitivity (NCWS) and Metabolic Dysfunction-Associated Steatotic Liver Disease (MAFLD), in a retrospective cohort…
- Conditions
- Metabolic Dysfunction-Associated Steatotic Liver Disease, Non Celiac Wheat Sensitivity, Irritable Bowel Syndrome, Functional Dyspepsia
- Trial name
- NCT07750535
- Testing
- Prevalence and severity of liver steatosis and fibrosis,
- Where
- 2 sites in Italy
- Volunteers
- 250 people
- Sponsor
- University of Palermo
Allergy;Food, Wheat Allergy
Randomized Controlled Trial for Wheat Oral Immunotherapy
IgE-mediated wheat allergy is a growing allergy problem in children, and affected children can predict with immediate-type allergic reactions to the extent of anaphylactic shock.
- Conditions
- Allergy;Food, Wheat Allergy, Children
- Trial name
- WOIT-RCT (NCT06069492)
- Testing
- Wheat-containing food
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Non-celiac Gluten Sensitivity
Tolerability of an Ancient Grain in Patients With Non-Celiac Wheat Sensitivity
Patients suffering from wheat-related troubles, in absence of celiac disease or wheat allergy diagnosis, can suffer from non-celiac wheat sensitivity (NCWS).
- Trial name
- NCT06191432
- Testing
- Administration of Triticum Monococcum flour, Administration of Triticum Aestivum flour
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- University of Palermo
Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome)
NCWS or IBS/FD in Relatives of CD Patients
Over 50% of non-celiac wheat sensitivity (NCWS) patients are HLA DQ2/DQ8 positive and often have a Celiac Disease (CD) family history.
- Conditions
- Non Celiac Wheat Sensitivity, IBS (Irritable Bowel Syndrome), Functional Dyspepsia, Celiac Disease
- Trial name
- NCT07584473
- Testing
- Wheat-Free Diet
- Where
- 2 sites in Italy
- Volunteers
- 600 people
- Sponsor
- University of Palermo