Clinical trials: Wheezing
Lung Disease, Obstructive, Signs and Symptoms, Respiratory
The Effect of Montelukast Treatment in Wheezy Infants
The study is designed to evaluate the efficacy of montelukast on symptom-free days in unselected group of very young children with wheeze and recurrent asthma like symptoms.
- Trial name
- Montelukast (NCT00934713)
- Testing
- montelukast
- Where
- Finland
- Volunteers
- 112 people
- Sponsor
- University of Helsinki
Asthma, Smoking Cessation
Pediatric Emergency Department Decision Support System to Reduce Secondhand Smoke
This two phase study will develop and evaluate a Pediatric Emergency Department (PED) Decision Support System (DSS)-Electronic Medical Records (EMR) System to facilitate the identification of smokers and the delivery of a Second…
- Trial name
- NCT02489708
- Testing
- Cessation Counseling
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Respiratory Syncytial Virus Infections
A Long-term Follow-up Study to Evaluate the Impact of Lumicitabine on the Incidence of Asthma and/or Wheezing in Infants and Children With a History of Respiratory Syncytial Virus Infection
The purpose of this long-term follow-up (LTFU) study is to evaluate the incidence of the clinical diagnosis of asthma and the frequency of wheezing in infants and children with respiratory syncytial virus (RSV) infection who were…
- Trial name
- NCT03332459
- Testing
- Lumicitabine
- Where
- 4 sites in Japan
- Volunteers
- 7 people
- Sponsor
- Janssen Research & Development, LLC
Benign Joint Hypermobility Syndrome, Wheezing
A Study to Assess Benign Joint Hypermobility Syndrome in Children With a History of Wheezing or Asthma
The purpose of this study is to assess benign joint hypermobility syndrome (BJHS) in children with a history of wheezing or asthma.
- Conditions
- Benign Joint Hypermobility Syndrome, Wheezing, Asthma
- Trial name
- NCT02163096
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Louisville
Asthma, Respiratory Tract Infections
VItamin D in pregnanCy for prevenTion Of eaRlY Childhood Asthma
The overall aim of the study is to develop a nutritional preventive vitamin D supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that…
- Conditions
- Asthma, Respiratory Tract Infections, Gastrointestinal Infection, Croup
- Trial name
- VICTORY (NCT06570889)
- Testing
- Cholecalciferol D3, Olive oil
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Professor Klaus Bønnelykke
Lower Respiratory Tract Infection (LRTI), Recurrent Wheezing
Prevent Wheeze Trial
This trial investigates whether a single dose of dexamethasone will prevent recurrent wheezing in children at high-risk for asthma admitted to hospital with a lower respiratory tract infection (LRTI).
- Trial name
- PRE-WHEE (NCT07858773)
- Testing
- Dexamethasone 0.6 mg/kilogram body weight single dose
- Where
- 2 sites in Nepal, South Africa
- Volunteers
- 486 people
- Sponsor
- Norwegian University of Science and Technology
Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections
Assessing the Burden of Respiratory Syncytial Virus (RSV)
This study examines the impact of Respiratory Syncytial Virus (RSV) on people of all ages, from infants to the elderly. It uses hospital records collected between January 2018 and December 2024 to understand: How often does RSV…
- Conditions
- Respiratory Syncytial Virus (RSV) Infection, Acute Lower Respiratory Tract Infections, Bronchiolitis, Pneumonia
- Trial name
- NCT07015255
- Where
- United Arab Emirates
- Volunteers
- 1,500 people
- Sponsor
- Abu Dhabi Health Services Company
Asthma
Pilot Study of Pioglitazone for the Treatment of Moderate to Severe Asthma in Obese Asthmatics
Asthmatics who are significantly overweight tend to have more severe symptoms, more flare ups, and are more likely to have poorly-controlled asthma when compared to other asthmatics.
- Trial name
- GLITZ Asthma (NCT00634036)
- Testing
- pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Fernando Holguin
Wheezing
Montelukast in Children With Wheezing
In this study children with recurrent wheezing (>/= 2 episodes in the last 6 months)and aged less than 2 years will be enrolled as outpatients.
- Trial name
- NCT00775697
- Testing
- Montelukast
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Universita di Verona
Wheezing, LRTI
Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates.
The primary objective of this study is to reduce respiratory tract infections and wheezing in moderate-late preterms in the first years of life by bacterial lysate administration.
- Conditions
- Wheezing, LRTI, Premature
- Trial name
- PROTEA (NCT05063149)
- Testing
- Broncho-Vaxom
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Franciscus Gasthuis
Wheezy Bronchitis
Intravenous Magnesium in Wheezy Bronchitis
In infants and toddlers wheezy bronchitis is a common viral disease. To relieve wheezing symptoms bronchodilators or corticosteroids are commonly used but the efficacy is not always satisfactory.
- Trial name
- NCT01383655
- Testing
- Magnesium Sulfate
- Where
- Finland
- Volunteers
- 61 people
- Sponsor
- University of Oulu
Asthma, Pulmonary Function
VCSIP Follow-up Study
The overall aims of this protocol are to determine whether prenatal supplementation with vitamin C to pregnant smokers can improve pulmonary function and decrease wheeze at 5 years of age in their offspring.
- Conditions
- Asthma, Pulmonary Function, Wheezing, In Utero Nicotine
- Trial name
- VCSIPRenewal (NCT03203603)
- Testing
- No active intervention
- Where
- 2 sites in United States
- Volunteers
- 242 people
- Sponsor
- Oregon Health and Science University
Allergic Rhinitis, Asthma
The Effect of Cetirizine on Bronchoconstriction
The purpose of this study is to determine the effect of cetirizine, an oral antihistamine, on wheezing in patients with allergic rhinitis.
- Trial name
- NCT03340740
- Testing
- Cetirizine Hydrochloride 1 MG/ML
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- New York City Health and Hospitals Corporation
Pneumonia, Perception, Self
Pneumonia Perception Project-Pakistan
Pneumonia and recurrent wheeze contribute extensively to under five childhood morbidity and mortality in Pakistan. Among the avoidable causes of death due to these diseases, delayed care seeking is a major one whereby around 38%…
- Trial name
- NCT03756259
- Testing
- Mobile Health (mHealth) for Pneumonia
- Where
- Pakistan
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh