Clinical trials: White Blood Cell Count
Cyclic Neutropenia, Congenital Neutropenia
Serial Blood Count Study
The objective of the Serial Blood Count Study is to determine the utility of home monitoring of white blood cell (WBC) and absolute neutrophil counts (ANC) to diagnose cyclic neutropenia and distinguish between cyclic and severe…
- Conditions
- Cyclic Neutropenia, Congenital Neutropenia, Neutropenia
- Trial name
- NCT07066085
- Testing
- Serial Blood Count Study, Athelas Home device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Acute Biphenotypic Leukemia, Acute Myeloid Leukemia
Cladribine, Idarubicin, Cytarabine, and Venetoclax in Treating Patients With Acute Myeloid Leukemia, High-Risk Myelodysplastic Syndrome, or Blastic Phase Chronic Myeloid Leukemia
This phase II trial studies how well cladribine, idarubicin, cytarabine, and venetoclax work in patients with acute myeloid leukemia, high-risk myelodysplastic syndrome, or blastic phase chronic myeloid leukemia.
- Conditions
- Acute Biphenotypic Leukemia, Acute Myeloid Leukemia, Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Blasts 10 Percent or More of Bone Marrow Nucleated Cells
- Trial name
- NCT02115295
- Testing
- Cladribine, Cytarabine, Gilteritinib
- Where
- United States
- Volunteers
- 508 people
- Sponsor
- M.D. Anderson Cancer Center
Abdominal Aortic Aneurysm, Coronary Artery Disease
White Blood Cell Counts and Onset of Cardiovascular Diseases: a CALIBER Study
The complete blood count is a commonly performed blood test, and previous small studies have suggested that the counts of some types of white blood cell in the complete blood count may be related to the onset of cardiovascular…
- Conditions
- Abdominal Aortic Aneurysm, Coronary Artery Disease, Stroke, Heart Failure
- Trial name
- CALIBER (NCT02014610)
- Volunteers
- 800,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Breast Cancer, Chemotherapy-Induced Neutropenia
Correlation Between ANC and Bone Pain in Breast Cancer Patients Receiving Long-Acting G-CSF
This prospective, multicenter, non-randomized controlled study aims to evaluate bone pain associated with prophylactic use of long-acting granulocyte colony-stimulating factors (G-CSFs) in patients with breast cancer receiving…
- Conditions
- Breast Cancer, Chemotherapy-Induced Neutropenia, Febrile Neutropenia, Bone Pain
- Trial name
- Bone Pain (NCT07806084)
- Volunteers
- 132 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Bone Marrow Suppression, Fever, Sweats, and Hot Flashes
Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count
RATIONALE: Antibiotic therapy may prevent the development of infection in patients with hematologic cancer and the persistent fever caused by a low white blood cell count.
- Conditions
- Bone Marrow Suppression, Fever, Sweats, and Hot Flashes, Infection, Leukemia
- Trial name
- NCT00003805
- Testing
- piperacillin sodium, piperacillin-tazobactam, tazobactam sodium
- Where
- 28 sites in United States, Belgium and 11 more
- Volunteers
- 859 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Oral Squamous Cell Carcinoma (OSCC), Premalignant Lesion
Comparison of TLC (Total Leucocyte Count), Neutrophils and Monocytes in Oral Squamous Cell Carcinoma and Pre-malignant Disorders
Oral squamous cell carcinoma is one of the significant public health concerns and the most prevalent malignancies affecting the head and neck region globally.
- Trial name
- NCT07899255
- Testing
- CBC will be required to assess the level of TLC (Total Leucocyte Count), Neutrophils and Monocytes in patient of oral squamous cell carcinoma and oral pre malignant conditions, using different stains
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Dow University of Health Sciences
Breast Cancer, Lung Cancer
Prognostic Value of Divpenia and CD4 Count in Relapsed Breast or Lung Cancer Patients
The T and B cells repertoire diversity represent one of the immune defence level which controls the integrity of the organism and determines its ability to recognize and control infectious attacks and development of tumours.
- Trial name
- LYMPHOS1 (NCT01306188)
- Testing
- Breast cancer cohort, Lung cancer cohort
- Where
- 4 sites in France
- Volunteers
- 179 people
- Sponsor
- Centre Leon Berard
Multiple Sclerosis
Study Of White Blood Cells In The Cerebrospinal Fluid And Blood Of Patients With Relapsing Forms Of Multiple Sclerosis
This is a study to count the number of white blood cells in the cerebrospinal fluid and blood at the beginning and end of treatment with firategrast and at 4 and 12 weeks after stopping firategrast.
- Trial name
- NCT00469378
- Testing
- firategrast
- Where
- 10 sites in Belgium, Czechia and 3 more
- Volunteers
- 46 people
- Sponsor
- GlaxoSmithKline
All Conditions Causing Sepsis, Pneumonia - Bacterial
Comparison Between the Progostic Value of the Procalcitonin and the Platelet/Total Leukocytic Count Ratio in Sepsis
What is already known on this subject? AND What does this study add? Sepsis is a complicated condition caused by a malfunction of the host's immune response to infection, which results in an uncontrollable inflammatory response…
- Conditions
- All Conditions Causing Sepsis, Pneumonia - Bacterial, Urinary Tract Infection Bacterial
- Trial name
- NCT06991686
- Testing
- Blood samples, blood sample
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Colorectal Cancer
Inflammation Biomarkers in the Diagnosis of Postoperative Infectious Complications in Colorectal Cancer Surgery
This is a longitudinal, single-center, prospective study to determine the efficiency of WBC Count, CRP, PCT, Neutrophil CD64 and Monocyte Human Leukocyte Antigen- DR in the diagnosis of postoperative infectious complications in…
- Trial name
- NCT03559335
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Neutropenia (Low White Blood Cell Count)
A Study to Compare the Pharmacokinetics, Pharmacodynamics, Immunogenicity, Safety and Tolerability of Filgrastim Biosimilar and Neupogen Reference Product in Healthy Volunteers
The goal of this clinical trial is to assess the pharmacokinetic similarity of Biofilgragen, a filgrastim biosimilar, compared with EU-authorized Neupogen after single subcutaneous doses in healthy adult volunteers.
- Trial name
- FIL-BIO-IMG (NCT07877467)
- Testing
- Biofilgragen, Neupogen (filgrastim)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- BioGeneric Pharma
Enhanced Recovery After Thoracic Surgery Protocol, C-reactive Protein
Enhanced Recovery After Thoracic Surgery
Despite significant advances in perioperative care, major complications continue to be seen in patients undergoing major surgery.
- Conditions
- Enhanced Recovery After Thoracic Surgery Protocol, C-reactive Protein, White Blood Cell Count, Neutrophil/Lymphocyte Ratio
- Trial name
- NCT05329311
- Testing
- ERATS protocol applied, ERATS protocol not applied
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Acute Ischemic Stroke (AIS)
Acute Ischemic Stroke Involves Significant Inflammatory Response. This Prospective Cohort Study Evaluates the Predictive Value of Monocyte-, Neutrophil-, and Leukocyte-to-albumin Ratios for Stroke Severity and Functional Outcome Using NIHSS at Admission and Modified Rankin Scale During Follow-up.
Acute Ischemic Stroke is a leading cause of mortality and long-term disability worldwide. Increasing evidence suggests that systemic inflammation plays a significant role in the pathophysiology and progression of ischemic brain…
- Trial name
- ALARMS (NCT07471061)
- Volunteers
- 60 people
- Sponsor
- Sohag University
Covid19
How Routine Biomarkers and Blood Leucocytes Count Can Assist Diagnosis of COVID-19 in Emergency Department
December 2019 was the onset of an outbreak of an infection related to SARS-CoV-2, a new coronavirus detected in January 2020 and responsible for a disorder termed COVID-19.
- Trial name
- MONACOVID (NCT04401241)
- Where
- Monaco
- Volunteers
- 257 people
- Sponsor
- Centre Hospitalier Princesse Grace
Neutropenia
Maintaining a Higher Level of Haemoglobin: Effect on the White Cells After Bone Marrow Transplantation in Children.
The purpose of this study is to determine if maintaining a high hemoglobin level in children that underwent bone marrow transplant will accelerate the neutrophil recovery.
- Trial name
- NCT00937053
- Testing
- Transfusion level 120 g/dL, Transfusion level 70 g/dL, Platelet transfusion
- Where
- 5 sites in Canada
- Volunteers
- 6 people
- Sponsor
- St. Justine's Hospital
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Myocardial Infarction
Platelet Leukocyte Aggregates in Acute Cardiac Syndrome vs Healthy Volunteers
This project aims to refine previous studies including the investigators work recently published in August 2012 Journal Thrombosis and Thrombolysis.
- Trial name
- NCT01797016
- Where
- Israel
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Breast, Breast Cancer
Self Reported Pain in Women While Undergoing Treatment for Non-metastatic Breast Cancer
The overall purpose of this study is to investigate whether younger subjects report pain with pegfilgrastim (or biosimilar substitution) more often and/or at higher levels (greater intensity) than older subjects.This study will…
- Trial name
- NCT04174742
- Testing
- pegfilgrastim
- Where
- 2 sites in United States
- Volunteers
- 115 people
- Sponsor
- Wake Forest University Health Sciences