Clinical trials: White Matter Disease
White Matter Disease, Right-to-left Shunt
The Relationship Between Right-to-left Shunt and Brain White Matter Lesions in Patients With Migraine
The purpose of the study is to evaluate the prevalence of white matter lesions in Chinese migraineurs with and without right-to-left shunt.
- Conditions
- White Matter Disease, Right-to-left Shunt, Migraine Disorders
- Trial name
- CAMBRAIN (NCT03418766)
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Huntington Disease, White Matter Alterations
Decoding Presymptomatic White Matter Changes in Huntington Disease
WIN-HD is a monocentric longitudinal study comparing premanifest Huntingtin (HTT) mutation carriers and non HTT mutation carriers to determine that white-matter atrophy occurs far earlier than clinical onset in HD using…
- Trial name
- Win-HD (NCT03193099)
- Testing
- Brain imaging, Neurological assessments, Psychological assessments
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alzheimer Disease, White Matter Hyperintensities
Brain Vascular Disease in Aging and Dementia
This study examines the factors that may drive the relationship between vascular disease and Alzheimer's Disease (AD) in a large, longitudinal, multi-ethnic community-based cohort study of older adults in northern Manhattan, New…
- Conditions
- Alzheimer Disease, White Matter Hyperintensities, Dementia, Aging
- Trial name
- NCT03075007
- Testing
- Florbetaben F18, Transcranial Doppler
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Columbia University
Infant, Premature, Diseases, Brain White Matter Disease Periventricular
Initial Efficacy Study of Supporting Play, Exploration, & Early Development Intervention
The primary aims of this randomized controlled trial are to evaluate efficacy potential of SPEEDI at enhancing reaching and play based problem solving compared to infants receiving usual care.
- Trial name
- SPEEDI (NCT02153736)
- Testing
- SPEEDI Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Encephalopathy, White Matter Hyperintensities
Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease
The purpose of this study is to extend our previous work, in which we demonstrated an increase in the internal and cross network connectivity of resting state neural networks in patients with cerebral small vessel disease by…
- Conditions
- Encephalopathy, White Matter Hyperintensities, Impaired Oxygen Delivery
- Trial name
- HBO (NCT02232958)
- Testing
- Hyperbaric Oxygen Treatment
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's Hospital, Chesterfield, Missouri
Ischemic White Matter Disease, Transient Ischemic Attack
Cognitive Changes and Rehabilitation in People With Transient Ischemic Attack, Stroke, or Stroke Risk Factors
Stroke is a leading cause of disability; most strokes (80%) are subcortical, with ischemic damage due to occlusion in penetrating arteries.
- Conditions
- Ischemic White Matter Disease, Transient Ischemic Attack, Mild Stroke, Stroke Risk
- Trial name
- NCT01951612
- Testing
- Executive Function Training Program, Psychoeducational Training Program
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Baycrest