Clinical trials: Withdrawal
Neonatal Abstinence Syndrome
Donor Human Milk in Neonatal Abstinence Syndrome
This study is designed to develop pilot data on the acceptability and benefit of donor human milk for infants undergoing pharmacologic treatment for NAS.
- Trial name
- DHM&NAS (NCT02182973)
- Testing
- donor human milk
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Neolac Inc dba Medolac Laboratories
Obstructive Sleep Apnoea
Randomized-controlled Trial (RCT) on CPAP-withdrawal and Microvascular Function in OSA
Randomized controlled trial (therapeutic vs. placebo CPAP) including 46 patients with obstructive sleep apnea (OSA) to define the physiological effects of continuous positive airway pressure (CPAP) therapy withdrawal on…
- Trial name
- NCT01797653
- Testing
- CPAP therapy withdrawal, Continue CPAP treatment
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- University of Zurich
Laryngeal Mask Airway Removal, Respiratory Complication
Timing of Withdrawal of the Laryngeal Mask Airway (LMA) in Children
The purpose of this prospective, randomized study was to compare the incidence of adverse events associated with removal of the LMA either in deeply anesthetised or awake patients.
- Trial name
- NCT03105739
- Testing
- LMA removal
- Where
- Tunisia
- Volunteers
- 148 people
- Sponsor
- Hôpital d'enfants Béchir-Hamza
Marijuana Dependence
Effectiveness Study of Dronabinol and BRENDA for the Treatment of Cannabis Withdrawal
This treatment study is targeted specifically for those who want to stop using marijuana. We want to find out if patients who are dependent on marijuana and want to stop using are helped by a combination of the drug dronabinol…
- Trial name
- NCT00480441
- Testing
- Dronabinol, BRENDA therapy
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Pennsylvania
Chronic Obstructive Pulmonary Disease, Hypercapnic Respiratory Failure
Withdrawal of Non-invasive Ventilation in Chronic Obstructive Pulmonary Disease (COPD) Patients With Acute Hypercapnic Respiratory Failure
The investigators design a pilot randomised, single-centred, controlled trial to compare different withdrawal methods of Non-invasive ventilation.
- Trial name
- NCT01523470
- Testing
- BIPAP Synchrony
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Schizophrenia
Monotherapy Brexpiprazole (OPC-34712) Trial in the Treatment of Adults With Early-Episode Schizophrenia
The purpose of this study is to investigate the effects of flexibly dosed Brexpiprazole monotherapy in the improvement of early-episode schizophrenia through the assessment of social functioning, efficacy, and tolerability.
- Trial name
- NCT02013622
- Testing
- Brexpiprazole
- Where
- 22 sites in United States
- Volunteers
- 49 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
COPD, Inhaled Corticosteroid
Inhaled Corticosteroid Withdrawal in Chronic Obstructive Pulmonary Disease (COPD)
According to the WISDOM study, withdraw of inhaled steroids has no effect on the acute exacerbation of chronic obstructive pulmonary disease (COPD), but the lung function of patients with COPD is significantly reclined.
- Trial name
- NCT04456205
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Nicotine Dependence
Study of Varencline Effects on Cigarette Smoking Reward and Craving During a Model of Brief Quit Attempt
Study of varenicline 2.0 mg/day treatment for 2 weeks with smoking test done in laboratory on Day 8 and a 1 week quit attempt from Day 8-14.
- Trial name
- VarenSmoke (NCT00571805)
- Testing
- varencline
- Where
- United States
- Sponsor
- NYU Langone Health
Smoking Cessation
Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation
Quitting smoking is a big decision, a decision to achieve better health. Trying to quit smoking can be stressful. The prospect of dealing with withdrawal symptoms, fear or failure to change the routine, can also be sources of…
- Trial name
- NCT02492022
- Testing
- Probiotic L008-1, Probiotic L008-2
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Lallemand Health Solutions
HEADACHE
Efficacy Evaluation Of Great Occipital Nerve Electrical Stimulation On Rebound Headache
SENGO-CAM study is a sham-controlled simple blind trial which aim is to study the efficacy of great occipital nerve stimulation (GONS) associated with medication withdrawal in the treatment of medication overuse headache…
- Trial name
- NCT01184222
- Testing
- great occipital nerve stimulation
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Nicotine Exposure, Nicotine Withdrawal Suppression
The Effect of Electronic Cigarette (ECIG) Liquid Vehicles on ECIG Acute Effects
This study examines the acute effects in ECIG users of the two primary vehicles in ECIG liquids, propylene glycol and vegetable glycerin.
- Trial name
- NCT02500615
- Testing
- ECIG liquid vehicles
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Criteria of Vulnerability
Impact of an Early Palliative Approach
Rationale: Medicalized end of life rose profound society questions and debates. Major Laws and scientific society recommendations emerged from those reflections.
- Trial name
- LATAREA-IV (NCT02471976)
- Testing
- strategy promoting early consideration and collegiate vulnerability of patients
- Where
- France
- Volunteers
- 1,172 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Recurrent Pericarditis
Study to Assess the Efficacy and Safety of Rilonacept Treatment in Participants With Recurrent Pericarditis
The primary objective of this study was to assess the efficacy of rilonacept treatment in participants with recurrent pericarditis.
- Trial name
- RHAPSODY (NCT03737110)
- Testing
- Rilonacept
- Where
- 21 sites in United States, Australia and 2 more
- Volunteers
- 86 people
- Sponsor
- Kiniksa Pharmaceuticals (UK), Ltd.
Kidney Transplantation
Observation Study for Prediction of Allograft Survival and Impact of Imaging in Kidney Transplant Recipients.
To further develop personalized medicine in kidney transplantation and improve transplant patient outcomes, attention has been given to define early surrogate endpoints that might aid therapeutic interventions, and help clinical…
- Trial name
- NCT03764124
- Testing
- PET/CT imaging
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University of Liege
Tourette Disorder
Ecopipam Tablets to Study Tourette's Disorder in Children, Adolescents and Adults
This Phase 3 multicenter study evaluates the maintenance of efficacy, safety and tolerability of ecopipam tablets in children, adolescents and adults in the treatment of Tourette's Disorder (TD).
- Trial name
- D1AMOND (NCT05615220)
- Testing
- Ecopipam Hydrochloride
- Where
- 95 sites in United States, Bulgaria and 10 more
- Volunteers
- 216 people
- Sponsor
- Emalex Biosciences Inc.
Quality of Life, Contraceptive Device; Complications
Impact of ESSURE Devices Withdrawal on the Symptomatology of Patients
The ESSURE device is a method of permanent contraception, marketed in France since 2005. Multiple side effects have been reported by patients since 2015 and the marketing was stopped in 2017.
- Trial name
- ESSURE (NCT03623126)
- Testing
- Questionnaire
- Where
- 2 sites in France
- Volunteers
- 41 people
- Sponsor
- Hospices Civils de Lyon
Opioid-Related Disorders
Activity Monitoring Assessment of Opiate Withdrawal - 4
The purpose of this study is to determine if hyperactivity accompanies abrupt opiate withdrawal in heroin addicts, to determine if computerized solid state activity monitors are capable of quantifying hyperactivity, and to…
- Trial name
- NCT00000335
- Testing
- Morphine
- Where
- United States
- Sponsor
- National Institute on Drug Abuse (NIDA)
Thyroid Cancer
CASE 1320: RAI Uptake and Serum Prolactin in Thyroid Cancer
Radioactive iodine (RAI) is a radioisotope used to ablate thyroid gland remnant after thyroidectomy in patients diagnosed with differentiated thyroid carcinoma (DTC).
- Trial name
- NCT04495985
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- The Cleveland Clinic
Low Back Pain
A Trial on the Effect on Low Back Pain Related Disability of Different Health Education Programs for Retired Persons
The primary purpose of this study is to compare, in retired persons living in the Balearic Islands, the effectiveness on low back pain related disability of three educational programs.
- Trial name
- NCT00441038
- Testing
- The Back Guide, The Back Book, Cardiovascular and general health
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kovacs Foundation
Opioid Withdrawal, Postoperative Pain
Opioid Tapering After Spine Surgery
The effect of a tapering plan combined with telephone counselling to assist patients in opioid tapering after surgery remains unexplored.
- Trial name
- NCT04140955
- Testing
- Tapering plan and telephone counselling
- Where
- Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.