Clinical trials: Women With Breast Cancer
Breast Cancer, Colorectal Cancer
Randomized Trial Evaluating the Effectiveness of the General Practitioner Involvement in Cancer Screening Invitations
Our goal is to evaluate, in France, the effectiveness (in terms of participation) of the general practitioner involvement (signature) and a more personalized communication in invitation letters to organized screening of breast…
- Conditions
- Breast Cancer, Colorectal Cancer, Cervical Cancer
- Trial name
- GPs (NCT02367001)
- Testing
- Normal invitation, revised invitation signed by the coordinating doctor, Revised invitation signed by the attending physician
- Where
- France
- Volunteers
- 53,978 people
- Sponsor
- University Hospital, Tours
Increased Risk for Development of Breast Cancer
Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers
Pilot study to test feasibility of 6 months of bazedoxifene (BZA) plus conjugated estrogens (CE) to modulate breast MRI parameters.
- Trial name
- NCT04821375
- Testing
- bazedoxifene plus conjugated estrogens
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Breast Cancer
Radiation Therapy (WBI Versus PBI) in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy in different ways may kill any tumor cells that remain after surgery.
- Trial name
- NCT00103181
- Testing
- 3-dimensional conformal accelerated partial breast irradiation, brachytherapy, whole breast irradiation
- Where
- 387 sites in United States, Canada and 2 more
- Volunteers
- 4,216 people
- Sponsor
- NSABP Foundation Inc
Breast Cancer
Fulvestrant With or Without Lapatinib and/or Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer That Progressed After Previous Aromatase Inhibitor Therapy
RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using fulvestrant and exemestane, anastrozole, or letrozole may fight breast cancer by blocking the use of estrogen by the tumor cells and by…
- Trial name
- NCT00688194
- Testing
- anastrozole, exemestane, fulvestrant
- Where
- Italy
- Volunteers
- 396 people
- Sponsor
- Gruppo Italiano Mammella (GIM)
BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ
Identifying and Caring for Individuals With Inherited Cancer Syndrome
This trial examines approaches to identify and care for individuals with inherited cancer syndrome. The purpose of this study is to offer no cost genetic testing to the general public.
- Conditions
- BRCA1/2-Associated Hereditary Breast and Ovarian Cancer Syndrome, Breast Ductal Carcinoma In Situ, Hematopoietic and Lymphoid System Neoplasm, Hereditary Neoplastic Syndrome
- Trial name
- NCT04494945
- Testing
- Biospecimen Collection, Genetic Counseling, Genetic Testing
- Where
- 2 sites in United States
- Volunteers
- 27,500 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Breast Cancer, Breast Cancer Female
An Exploratory Study of Surufatinib Combined With Chidamide and Fulvestrant in HR Positive Unresectable Metastatic Breast Cancer
This is a prospective, single center, single arm phase II study designed to explore the efficacy and safety of surufatinib + fulvastrant + chidamide combinational treatment in HR positive breast cancer refractory to endocrine…
- Trial name
- NCT05186545
- Testing
- surufatinib + fulvestrant + chidamide
- Where
- 5 sites in China
- Volunteers
- 63 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Breast Cancer
Internet Use Among Women With Recurrent Metastatic Breast Cancer
RATIONALE: Gathering information about patients with breast cancer over time may help doctors learn more about a patient's use of the internet to find information about treatment, symptom management, and emotional support.
- Trial name
- NCT00770055
- Testing
- medical chart review, questionnaire administration, survey administration
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Breast Cancer, HER2-negative Breast Cancer
Comparison of Neoadjuvant Chemotherapy With Weekly Paclitaxel or Eribulin Followed by A/C in Women With Locally Advanced HER2-Negative Breast Cancer
NSABP FB-9 is a Phase II, multi-center, randomized study of eribulin or weekly paclitaxel followed by doxorubicin and cyclophosphamide (AC) as neoadjuvant therapy for women with HER2-negative, operable and locally advanced breast…
- Trial name
- NCT01705691
- Testing
- Paclitaxel, Eribulin, Doxorubicin
- Where
- 20 sites in United States, Canada
- Volunteers
- 50 people
- Sponsor
- NSABP Foundation Inc
Breast Cancer
Combination Chemotherapy With Trastuzumab in Treating Women With Metastatic Breast Cancer
RATIONALE: Drugs used in chemotherapy such as cyclophosphamide, methotrexate, and fluorouracil use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00036868
- Testing
- trastuzumab, CMF regimen, cyclophosphamide
- Where
- 13 sites in Belgium, Denmark and 7 more
- Volunteers
- 90 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Early Breast Cancer
Pregnancy Outcome and Safety of Interrupting Therapy for Women With Endocrine Responsive Breast Cancer
The best available evidence suggests that pregnancy after breast cancer does not increase a woman's risk of developing a recurrence from her breast cancer.
- Trial name
- POSITIVE (NCT02308085)
- Testing
- Endocrine therapy interruption
- Where
- 211 sites in United States, Australia and 20 more
- Volunteers
- 518 people
- Sponsor
- ETOP IBCSG Partners Foundation
Breast Cancer, Osteoporosis
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
RATIONALE: Zoledronate may reduce bone loss in patients receiving letrozole for breast cancer. PURPOSE: This clinical trial is studying how well zoledronate works in treating osteopenia or osteoporosis in postmenopausal women…
- Trial name
- NCT00436917
- Testing
- zoledronic acid, Letrozole as adjuvant therapy
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Breast Cancer
Anti-tumour Effects & Tolerability of Faslodex Alone or in Combination With Arimidex in Post Menopausal Women Prior to Surgery for Primary Breast Cancer
To compare the anti-tumour effects as measured by changes in various biomarkers, of a combination of Faslodex and Arimidex with Faslodex alone and Arimidex alone in postmenopausal women patients with primary breast cancer who are…
- Trial name
- NCT00259090
- Testing
- Fulvestrant, Anastrazole
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Breast Cancer
Circulating Fetal Cells and Breast Cancer
After pregnancy, fetal cells remain in a woman's body for years. These cells may be involved in different physiological situations (e.g. wound healing) and diseases (e.g.
- Trial name
- MoSaiC2 (NCT04903990)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
ER+ HER2- Advanced Breast Cancer
A Phase 1 Study of AZD9833 in Japanese Women With ER Positive, HER2 Negative Advanced Breast Cancer
This is a Phase 1, open-label study designed to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of AZD9833 in Japanese women with endocrineresistant ER+ HER2- breast cancer that is not amenable to…
- Trial name
- NCT04541433
- Testing
- AZD9833
- Where
- 3 sites in Japan
- Volunteers
- 10 people
- Sponsor
- AstraZeneca
Breast Cancer, Complementary Therapies
Supportive Effects of Craniosacral Therapy for Women With Breast Cancer
Craniosacral Therapy (CST) is a non-manipulative, very gentle, manual treatment method that aims to release restrictions of the fasciae and regulate the arousal of the sympathetic nervous system, which is often increased in…
- Trial name
- CRANIO4US (NCT04319510)
- Testing
- Craniosacral therapy, Craniosacral self-help group training, Treatment as usal / wait list
- Where
- 3 sites in Germany
- Volunteers
- 102 people
- Sponsor
- Universität Duisburg-Essen
Breast Cancer, Cardiac Toxicity
Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab
RATIONALE: Studying samples of blood and tissue in the laboratory from women receiving doxorubicin and trastuzumab for breast cancer may help doctors learn more about changes that occur in DNA and identify biomarkers for…
- Conditions
- Breast Cancer, Cardiac Toxicity, Cardiovascular Complications
- Trial name
- PACE in BC (NCT00875238)
- Testing
- trastuzumab, doxorubicin hydrochloride, polymorphism analysis
- Where
- 4 sites in United States
- Volunteers
- 133 people
- Sponsor
- Vanderbilt University
Female, First-degree Relative With Breast Cancer
Physical Activity and First Degree Female Relatives of Breast Cancer Patients
The purpose of this study is to learn more about encouraging physical activity among first degree female relatives of women with breast cancer.
- Trial name
- NCT03115658
- Testing
- Physical Activity
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Neoplasms, Bone Loss
Bone Loss Treatment From Adjuvant Zoledronate Efficacy
The main purpose of this study is to observe and assess the impact of adjuvant zoledronate on bone density in breast cancer patients.
- Trial name
- BLAZE (NCT01623908)
- Testing
- Zoledronate
- Where
- 10 sites in China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Advanced Solid Tumor, Ovarian Cancer
NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors
NUV-868-01 is a first-in human, open- label, Phase 1/2 dose escalation and expansion study in patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumor, Ovarian Cancer, Ovary Cancer, Cancer of Ovary
- Trial name
- NCT05252390
- Testing
- NUV-868, Olaparib, Enzalutamide
- Where
- 22 sites in United States, Australia
- Volunteers
- 82 people
- Sponsor
- Nuvation Bio Inc.
Breast Cancer, BRCA Mutation
Patient Empowerment by Group Medical Consultations
Carriers of a BRCA mutation have a significantly increased risk to develop breast cancer in the course of their lives . They face a difficult choice: either a preventive removal of the breast(s) or an intensive inspection…
- Trial name
- GMC (NCT01329068)
- Testing
- individual consult, group medical consult
- Where
- Netherlands
- Volunteers
- 320 people
- Sponsor
- Radboud University Medical Center
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