Clinical trials: Women of Reproductive Age
Hyperandrogenism
Effects of Androgen Administration on Inflammation in Normal Women
The hypothesis of this study is that DHEA administration to increase male hormone in healthy normal-weight young women to levels present in women with Polycystic Ovary Syndrome will cause an inflammatory response in white blood…
- Trial name
- NCT01753037
- Testing
- Dehydroepiandrosterone (DHEA)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Infertility, Female
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)
This trial investigates the effects of FE 999049 compared to placebo.
- Trial name
- RITA-2 (NCT03738618)
- Testing
- Follitropin delta
- Where
- 24 sites in United States
- Volunteers
- 588 people
- Sponsor
- Ferring Pharmaceuticals
Cognitive Function and Mood, Non-anaemic Iron Deficiency
Efficacy Evaluation of 16 Weeks' Dietary Supplementation With Iron Bis-glycinate Plus Vitamin C on Cognitive Function, Subjective Mood, Fatigue, Health and Well-being
Iron deficiency is the most prevalent nutritional deficiency worldwide with one in four estimated to be affected by iron deficiency anaemia.
- Trial name
- NCT04469010
- Testing
- Iron Bis-Glycinate Chelate and Vitamin C, Iron Bis-Glycinate Chelate
- Where
- United Kingdom
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Pro- and Anti-inflammatory Cytokines in PCOS
The study will involve measurements and comparisons of the concentrations of pro-inflammatory cytokines: IL-6, TNF-α, IL-18, as well as anti-inflammatory cytokine IL-4 in women with polycystic ovary syndrome (PCOS) and insulin…
- Trial name
- NCT06793085
- Testing
- Measurement of interleukin-6 (il-6) concentration in blood serum, Measurement of fasting tumor necrosis factor α (TNF-α) concentration, Measurement of interleukin-18 (il-18) concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Advanced Maternal Age Pregnancy, Premature
Pregnancies Outcomes in Advanced Maternal Age Women
Pregnancies occurring in advanced maternal age (AMA) have become more common over the last few decades for a variety of reasons.
- Conditions
- Advanced Maternal Age Pregnancy, Premature, Labor Complication, Delivery Complication
- Trial name
- POIAMA (NCT06528340)
- Testing
- spontaneous delivery
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Type 1 Diabetes
Impact of the Menstrual Cycle in Reproductive Aged Women With Type 1 Diabetes Using a Closed Loop System (DIABETEXX/1).
The aim of this observational study is to assess the effectiveness of automatic insulin infusion in responding to changes in insulin sensitivity throughout various phases of the menstrual cycle in a cohort of reproductive-aged…
- Trial name
- DIABETEXX/1 (NCT06338072)
- Where
- Spain
- Volunteers
- 119 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Vitamin d, Vitamin B 12 and Folic Acid Concentrations, Micronutrient Status in Women of Reproductive Age
Vitamin B12, Folic Acid, and Vitamin D Status in Women of Reproductive Age
This cross-sectional observational study aims to assess serum concentrations of vitamin B12, folic acid, and vitamin D in women of reproductive age in Herzegovina.
- Conditions
- Vitamin d, Vitamin B 12 and Folic Acid Concentrations, Micronutrient Status in Women of Reproductive Age, Vitamin Status Assessment
- Trial name
- NCT07099586
- Testing
- No Interventions
- Where
- Bosnia and Herzegovina
- Volunteers
- 360 people
- Sponsor
- University of Mostar
Infertility, Female, Intracytoplasmic Sperm Injections
Piezo-ICSI to Improve the Developmental Potential of Fertilized Oocytes in Aged Infertility Women With Assisted Reproductive Technology
The goal of this clinical trial is to test Piezo-ICSI on improving oocyte fertilization and embryo development in elderly infertile patients undergoing intracytoplasmic sperm injection (ICSI).
- Trial name
- NCT06459778
- Testing
- Piezo-ICSI
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Diabetes Mellitus, Type 2, Gestational Diabetes
Prevention of Type 2 Diabetes and Gestational Diabetes Among Women in Kisantu, Democratic Republic of Congo
This study aims to develop and implement a long-term program focused on the prevention of type 2 diabetes Mellitus (T2DM) and gestational diabetes mellitus (GDM) in women of reproductive age through lifestyle modification.
- Trial name
- KIS-Antwerp (NCT05039307)
- Testing
- Educational and motivational strategy
- Where
- 6 sites in Democratic Republic of the Congo
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Iron-deficiency, Anemia
Iron-Biofortified Rice Intervention in the Philippines
The objective of this randomized efficacy feeding trial was to determine the effects of consuming iron-biofortified rice on iron status in women, compared to non-biofortified rice.
- Trial name
- NCT04623918
- Testing
- Iron-biofortified rice, Control rice
- Where
- Philippines
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Cornell University
Women, Reproductive Age
Enhancing Uptake of Preconception Care Services in Family Practice Clinics Using a Patient Centered Screening Tool
Sixteen years have passed since the Centers for Disease Control recommended routine preconception screening and counseling in primary care settings, yet time constraints and low preconception counseling adherence have prevented…
- Trial name
- NCT06582160
- Testing
- Risk-Based Pre-conception Screening, Patient-centered Pre-conception Screening
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Maternal Death
Maternal Health Service Utilization Among Women of Reproductive Age in Sidama Region, Ethiopia
Introduction: Maternal health service (MHS) utilization helps to decrease maternal morbidity and mortality. However, the existing evidence is not sufficient to design effective and efficient strategies.
- Trial name
- MHSU (NCT05865873)
- Testing
- Health education
- Where
- Ethiopia
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- Hawassa University
Uterine Fibroids Affecting Pregnancy
Composition for Treating Uterine Fibroid (SB-UF)
Pregnenolone \& Pyridoxal Phosphate SB-UF for treating uterine fibroids in women's pregnancies to lose the size of fibroids and to dissolve fibroids.
- Trial name
- SB-UF (NCT04762316)
- Testing
- SB-UF
- Where
- Vietnam
- Volunteers
- 66 people
- Sponsor
- Trieu, Nguyen Thi, M.D.
Folate Deficiency, Iodine Deficiency
Acceptability and Nutritional Impact of Double-fortified Salt Containing Iodine and Folic Acid
The overarching objective of this two-phase project is to assess the effects of fortifying iodized salt with folic acid on improving women's folate status.
- Conditions
- Folate Deficiency, Iodine Deficiency, Anemia Macrocytic, Anemia Deficiency
- Trial name
- DFS-IoFA-2 (NCT06223854)
- Testing
- Iodized salt, Experimental: Iodized salt with lower-dose folic acid fortification, Experimental: Iodized salt with higher-dose folic acid fortification
- Where
- Ethiopia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iron Deficiency
Iron Absorption From Tef-injera in Women of Reproductive Age
Anemia is one of the most common health problems all over the world with around half of preschool-aged children (<5 years) and one third of women affected.
- Trial name
- NCT01687062
- Testing
- FeSO4, reduction of phytate, NaFeEDTA
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
IVF
Ubiquinone vs. Ubiquinol Supplementation
The objective of this study is to determine if ubiquinol will result in improved reproductive outcomes in older women at a reduced oral dose compared to current standard treatment with ubiquinone.
- Trial name
- NCT06555575
- Testing
- Ubiquinone 200 Mg Oral Capsule, Ubiquinol 100 MG Oral Capsule
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Trio Fertility
Obesity
Folic Acid Supplementation in Women of Child Bearing Age
The objective of this study is to identify genes whose expression is potentially modifiable due to changes in folate intake and help delineate mechanisms accounting for the variability in individual response to folic acid…
- Trial name
- FASUPP (NCT01841658)
- Testing
- Folic acid
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Reproductive Age, PCOS (Polycystic Ovary Syndrome)
Functional Proteins in Polycystic Ovary Syndrome
The concentration of functional proteins: kisspeptin, ghrelin, zonulin will be measured and compared in women with polycystic ovary syndrome (PCOS) and insulin resistance (IR), in women with PCOS without IR, and in women without…
- Trial name
- NCT06793098
- Testing
- Measurement of kisspeptin concentration, Measurement of ghrelin concentration, Measurement of zonulin concentration
- Where
- Poland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Hodgkin Lymphoma
Gonadal Toxicity in Women With Hodgkin Lymphoma
The Gruppo Italiano Studio Linfomi has been collecting data on patients with Hodgkin Lymphoma (HL) since 1988. This archive represents a homogeneous series of consecutive patients with HL.
- Trial name
- FertHD (NCT01008735)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Gruppo Italiano Studio Linfomi
Bacterial Vaginosis, Vulvovaginal Candidiases
Light Treatment of Vaginal Infections in Reproductive Age Women
Antimicrobials have helped in managing vaginal dysbiotic conditions such as bacterial vaginosis (BV) and vulvovaginal candidiasis (VVC).
- Trial name
- NCT06985433
- Testing
- Vaginal light therapy - Once, Vaginal Light Therapy - Twice
- Where
- Denmark
- Volunteers
- 38 people
- Sponsor
- UVISA Health ApS