Clinical trials: Workflow, open to volunteers
Patient Centered Care, Integration in Clinical Workflows
Evaluating the Effectiveness of an AI-powered Physician Assistant in Improving Patients' and Physician's Satisfaction in an Outpatient Setting of a Tertiary Care Hospital.
Patients' satisfaction depends on several factors, including health care costs, access to care, and the waiting time to see a healthcare professional.
- Trial name
- NCT07756632
- Testing
- AI Physician Assistant
- Where
- Pakistan
- Volunteers
- 367 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Ovarian Cancer
Spatial Radiogenomics of Ovarian Cancer
The biological spatial and temporal heterogeneity of High Grade Serous Ovarian Carcinoma (HGSOC) severely impacts the effectiveness of therapies and is a determinant of poor outcomes.
- Trial name
- CO-MOULD (NCT06324175)
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Acute Ischemic Stroke and Transient Ischemic Attacks
Cardiac CT Angiography in Acute Stroke Imaging (SCOPE-CT)
Stroke can occur when a blood clot travels to the brain and blocks blood flow. In some patients, these blood clots may originate in the heart.
- Trial name
- SCOPE-CT (NCT07896889)
- Testing
- Cardiac CT Angiography
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Ottawa Hospital Research Institute
TMD
AMOUNT OF INTRAORAL OCCLUSAL ADJUSTMENTS IN OCCLUSAL SPLINTS FABRICATED USING FULLY DIGITAL VERSUS COMBINED DIGITAL WORKFLOW IN TMD PATIENTS
Each eligible patient will be randomly into one of two groups: group A: Occlusal splints fabricated using a fully digital workflow including the use of a jaw tracking device.
- Trial name
- NCT06752200
- Testing
- Occlusal splints fabricated using a fully digital workflow including the use of a jaw tracking device., Occlusal splints fabricated using a combined digital workflow using a conventional bite technique
- Volunteers
- 26 people
- Sponsor
- Cairo University
Sports Performance in Children
Effect of Digitally Produced Custom Mouthguards on the Awareness and Sports Performance of Child and Adolescent Basketball Players
The aim of the study is to investigate the effects of custom mouthguards, prepared using digital workflow, on the sports performance of children and adolescents who play basketball, and to evaluate their views on the use of…
- Trial name
- NCT06660836
- Testing
- Mouthguard, Performance test
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Liver Cancer, Intrahepatic Cholangiocarcinoma
REGULUS: MRI-guided Adaptive SABR for Liver Cancers
Single arm unblinded study of simulation-free MRI-guided SABR with adaptive replanning in one session for treatment of patients with liver cancers
- Conditions
- Liver Cancer, Intrahepatic Cholangiocarcinoma, Liver Metastases, HCC
- Trial name
- NCT07223307
- Testing
- MRI-guided adaptive stereotactic ablative body radiotherapy (SABR)
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Edentulous Maxilla
Clinical Study Investigating the Efficiency and Complications Related to Two Different Procedures Used for the Preparation of Dentures Applied in Patients With Edentulous
The principal aim of the study is to evaluate the prosthetic complications with CAD-CAM fabricated provisional prostheses and denture conversion prostheses after 3 months of function.
- Trial name
- NCT05332977
- Testing
- CAD-CAM fabricated provisional prosthesis, DC (denture conversion) provisional prosthesis
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Atrial Fibrillation, Stroke
AI-Assisted Workflow for Occult Atrial Fibrillation Detection After Ischemic Stroke: A Prospective Randomized Trial
We hypothesize that an AI-guided AF risk stratification approach, particularly when combined with intensified rhythm monitoring using wearable devices and extended ECG patches, will significantly increase AF detection rates…
- Conditions
- Atrial Fibrillation, Stroke, Artificial Intelligence
- Trial name
- AI-AFIS (NCT07540065)
- Testing
- Active Follow-up Group, Standard Follow-up Group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Jaw Tracking, Occlusion
Evaluation of the Impact of Integrating Dynamic Patient-Specific Motion and Implementing a Jaw Tracking System in the Attribution of the Occlusion in Full-Arch Restorations Through a Digital Workflow: A Clinical Study
The maxillomandibular relationship of diagnostic and definitive casts is a fundamental procedure in prosthodontics. Depending on the prosthodontic treatment involvement, different maxillomandibular relationship records can be…
- Trial name
- NCT06773728
- Testing
- Record occlusal contacts, Tracking of jaw movement
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Cancer
Introduction of Y90-PET-CT Post Radioembolisation Therapy Scans
Yttrium-90, attached to microspheres, usually referred to as 90Y-microspheres or Y-90 radioembolisation, can be used in some cases to treat patients with liver tumours or liver metastasis.
- Trial name
- Y90-PET-CT (NCT06123676)
- Testing
- Y90-PET-CT scan
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- The Christie NHS Foundation Trust
Chronic Atrophic Gastritis, Depressive Symptoms
Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis
Depressive symptoms are highly prevalent in patients with chronic atrophic gastritis (CAG) but are frequently under-detected due to stigma and reliance on subjective questionnaires.
- Conditions
- Chronic Atrophic Gastritis, Depressive Symptoms, Depression, Gastrointestinal Diseases
- Trial name
- NCT07319338
- Testing
- Vascular-Psychological Triage Workflow
- Where
- 4 sites in China
- Volunteers
- 520 people
- Sponsor
- China Academy of Chinese Medical Sciences
Pregnant Women
Cell-based Non-invasive Prenatal Test Workflow
The aim of this study is to optimize a new non-invasive prenatal screening method based on the capture of fetal cells from maternal blood and to complete its development by obtaining maternal blood samples during the first…
- Trial name
- TOTAL#5 (NCT07566780)
- Testing
- Blood collection
- Volunteers
- 1,400 people
- Sponsor
- Menarini Silicon Biosystems
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Complete Edentulism
Clinical Performance and Quality of Life of 3D-Printed Complete Dentures Under Digital vs Hybrid Workflows: A Randomized Crossover Trial
This prospective randomized crossover clinical trial evaluates and compares the clinical performance and oral health-related quality of life (OHRQoL) of complete dentures fabricated through two additive manufacturing workflows …
- Trial name
- PRINT-DENT (NCT07626827)
- Testing
- Digital Workflow Complete Denture, Hybrid Workflow Complete Denture
- Where
- Ecuador
- Volunteers
- 20 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Lung Cancer
Label-free Femtosecond Laser Imaging Combined With the Fast Lung Artificial Intelligence Model for Rapid Intraoperative Diagnosis of Lung Surgical Specimens: A Multicentre, Prospective, Parallel-workflow, Non-inferiority Study.
This study aims to evaluate whether femtosecond laser imaging combined with FastLung AI model can provide intraoperative diagnostic performance that is non-inferior to standard frozen section diagnosis for pulmonary nodules or…
- Trial name
- NCT07681245
- Testing
- Femtosecond Laser Imaging, Frozen Section Diagnosis
- Where
- 5 sites in China
- Volunteers
- 294 people
- Sponsor
- Shanghai Chest Hospital
Keratoconus, Refractive Surgery
AI-Orchestrated Workflow Versus Consultant Ophthalmologist for Refractive Surgery and Keratoconus Diagnosis (AEYE Trial)
Background and Rationale: Laser vision correction procedures, such as LASIK (Laser-Assisted In Situ Keratomileusis), PRK (Photorefractive Keratectomy), and SMILE (Small Incision Lenticule Extraction), are highly effective but…
- Conditions
- Keratoconus, Refractive Surgery, Machine Learning, Artifical Intelligence
- Trial name
- AEYE (NCT07096232)
- Testing
- Multi-Agent AI Diagnostic Workflow (AEYE)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Hazem Yassin Clinics
Informed Consent, Patient Education
Digital-Supported Versus Standard Consent for Advanced Therapeutic Endoscopy
This study will evaluate whether a digital-supported informed consent process improves patient understanding before advanced therapeutic endoscopy procedures.
- Conditions
- Informed Consent, Patient Education, Patient Comprehension, Therapeutic Endoscopy
- Trial name
- DIGI-CONSENT (NCT07723105)
- Testing
- Digital-Supported Informed Consent Pathway, Standard Physician-Led Informed Consent
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Unity Health Toronto
Socket Preservation, Implant-supported Single Crowns
Hyaluronic Acid and Polynucleotides in Ridge Preservation
The aim of this study is to test the use of a bovine-derived bone graft combined with a polynucleotides-rich hyaluronic acid (PNHA) gel for the preservation of the bone after a tooth extraction (alveolar ridge preservation) and…
- Conditions
- Socket Preservation, Implant-supported Single Crowns, Hyaluronic Acid, CAD-CAM
- Trial name
- P-005 (NCT07099846)
- Testing
- regeneration of post extraction socket with biomaterials
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Study Aims to Develop and Validate a Generative AI-assistant Designed to Optimize Radiologists' Workflows and to Evaluate Its Performance
Generative AI Radiologist's Workstation
This study aims to develop a generative AI assistant for radiologists to automate the processing of electronic medical records (EMRs) and provide relevant clinical information, optimizing diagnostic interpretation workflows.
- Trial name
- GARW (NCT07057830)
- Where
- 2 sites in Russia
- Volunteers
- 27 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Interstitial Lung Disease (ILD), Suspected Interstitial Lung Disease
Optimizing the Diagnostic Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-1 Trial
The OPTIMIZE-ILD-1 trial is a prospective, randomized, open-label clinical trial designed to evaluate the impact of a coordinated diagnostic pathway on patients with suspected interstitial lung disease (ILD).
- Conditions
- Interstitial Lung Disease (ILD), Suspected Interstitial Lung Disease, Fibrotic Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis (IPF)
- Trial name
- OPTIMIZE-ILD-1 (NCT07482917)
- Testing
- Standard ILD Diagnostic Pathway, Optimized ILD Diagnostic Circuit
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Hospital de Granollers