Clinical trials: Wound Care
Wounds, Wound Heal
G-Wound (VZ for Wound Treatment)
This is a prospective, randomized, open-label, controlled, exploratory trial that aims to investigate the local skin tolerability of topically administered VZ and to evaluate efficacy and safety parameters associated with…
- Trial name
- NCT04417647
- Testing
- VZ powder (purified clinoptilolite), Standard of care (SoC)
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Glock Health, Science and Research GmbH
Trauma Injury, Acute Coronary Syndrome
Smart Glasses in Emergency Medicine From the Hangzhou Asian Games
The findings of our study will reveal that using smart glasses in the emergency department(ED) could facilitate patient admission. AR Smart Glasses offer the potential to enhance the effectiveness and speed of treatment within ED.
- Conditions
- Trauma Injury, Acute Coronary Syndrome, Stroke, Acute, Septic Shock
- Trial name
- SGINHZAG (NCT06623825)
- Testing
- teleconsultation by Augmented Reality smart glasses, teleconsultation by two-way radio connection.
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Sir Run Run Shaw Hospital
Firearm Violence, Firearm Carriage
Project IntERact V2
The present study is evaluating the efficacy of a behavioral intervention to reduce risky firearm carriage among a high risk sample of youth reporting recent firearm carriage and ownership of a smartphone.
- Conditions
- Firearm Violence, Firearm Carriage, Injury Prevention
- Trial name
- NCT05109325
- Testing
- IntERact
- Where
- 3 sites in United States
- Volunteers
- 373 people
- Sponsor
- University of Michigan
Traumatic Brain Injury, Caregiver Burden
m-Health Supportive Care Transition Program in Improving Post-Discharged Outcomes
This intervention study aims to investigate the effects of the m-Health supportive care transition program on response patterns (transition stress and the burden of caregiving) among traumatic brain injury (TBI) caregivers and…
- Conditions
- Traumatic Brain Injury, Caregiver Burden, Stress
- Trial name
- NCT05951335
- Testing
- m-Health Transition Care Program
- Where
- Thailand
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Acute Kidney Failure
Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
Acute kidney injury (AKI) is a major organ failure in septic shock. Current medical tests (serum creatinine and urea) cannot identify AKI until approximately 48 hours after it occurs.
- Trial name
- NESAKI (NCT01122225)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Université Victor Segalen Bordeaux 2
Covid-19, Family Members
Impact of Covid-19 Restrictive Measure on Anxiety, Depression and PTSD for Relatives of ICU Patients
To limit the pandemic Covid-19 infection, the French government imposed a closure of all Intensive Care Unit (ICU). The family's visitations are prohibited during active Covid -19 pandemic in 2020 and in 2021.
- Conditions
- Covid-19, Family Members, Critical Illness
- Trial name
- HAD-Covid (NCT04430049)
- Testing
- Covid ICU containment measures
- Where
- 11 sites in France
- Volunteers
- 811 people
- Sponsor
- University Hospital, Clermont-Ferrand
Spinal Cord Injuries
Assessment of the Effects of Early Proprioceptive Stimulations in Patients With Spinal Cord Injury
"Spinal cord injury (SCI) is a dramatic event resulting in a long-term handicap. Appropriate care from admission to the intensive care unit (ICU) is a key element not only for the survival of these patients but also to promote…
- Trial name
- Tetra-Mouv (NCT05094752)
- Testing
- Proprioceptive stimulations
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracoabdominal Trauma, Focused Assessment With Sonography for Trauma (FAST)
Comparing Use of a Prehospital Ultrasound System and Standard Prehospital Care in Thoracoabdominal Trauma
The NanoMaxx Ultrasound System (SonoSite) in connection with the RP-Xpress (InTouch Technologies) provides a means of transmitting ultrasound images, video, and audio to a remote location in real-time.
- Conditions
- Thoracoabdominal Trauma, Focused Assessment With Sonography for Trauma (FAST), NanoMaxx Ultrasound System (SonoSite), RP-Xpress (InTouch Technologies)
- Trial name
- FAST-01 (NCT02198885)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Saskatchewan
Systemic Oxygenation vs ROS Formation in TBI Patients
ROS in TBI Patients in Relation to Level of Oxygenation.
This project an observational study performed on patients with severe Traumatic Brain Injury (TBI) treated at Neurosurgical ICU (NICU) at Karolinska University Hospital.
- Trial name
- ROS-TBI (NCT05101278)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Region Stockholm
Solid Carcinoma, Post Traumatic Stress Disorder
Psychological Care of Oncology Patients With Post-traumatic Stress in the Context of a COVID-19
In the context of the COVID-19 pandemic, concerns of the risk of infection may lead to fear, anxiety or psychological disorders that may become generalised and long-lasting, corresponding to post-traumatic stress disorder (PTSD).
- Conditions
- Solid Carcinoma, Post Traumatic Stress Disorder, Covid19
- Trial name
- COVIPACT 2 (NCT04747249)
- Testing
- Psychological support
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Francois Baclesse
Critical Illness, Wounds and Injury
Strategy to Avoid Excessive Oxygen Using an Autonomous Oxygen Titration Intervention
This study is a multicenter randomized controlled trial to determine the effectiveness of a closed loop/autonomous oxygen titration system (O2matic PRO100) to maintain normoxemia (goal range SpO2 90-96%, target 93%) during the…
- Conditions
- Critical Illness, Wounds and Injury, Disease Attributes, Pathologic Processes
- Trial name
- SAVE-O2 AI (NCT06374225)
- Testing
- Automated Titration (O2matic)
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Colorado, Denver
Substance Use Disorders, Post-Traumatic Stress Disorder
Evaluating the Integration of Indigenous Healing With Principals of Seeking Safety for Treatment of Indigenous Patients With a History of Trauma and Active Substance Use Disorder.
Background: The negative health outcomes experienced by Indigenous peoples may be understood as direct consequences of colonization.
- Conditions
- Substance Use Disorders, Post-Traumatic Stress Disorder, Intergenerational Trauma
- Trial name
- NCT04604574
- Testing
- Indigenous Healing and Seeking Safety
- Where
- Canada
- Volunteers
- 550 people
- Sponsor
- Health Sciences North Research Institute
Diabetic Foot Ulcer
Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)
The purpose of this study is to determine how well our dHPT (Dehydrated Human Placental Tissue) Product and Standard of Care work when compared to Standard of Care alone in achieving complete closure of diabetic foot.
- Trial name
- ELITE (NCT07014176)
- Testing
- Amnion-Intermediate-Chorion, Standard of Care (SOC)
- Where
- 8 sites in United States
- Volunteers
- 84 people
- Sponsor
- Cellution Biologics
Dementia, Traumatic Brain Injury
Improving Family Quality of Life Through Training to Reduce Care-Resistant Behaviors by People With AD and TBI
To reduce care resistant behaviors (CRB) among people with dementia residing in nursing homes, to a distance-learning education, training, and coaching program for family caregivers of people with dementia or TBI; assess the…
- Trial name
- NCT03734289
- Testing
- Caregiver Coaching
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hip Fractures
Precision Care for Older Persons
This study aims to 1) develop an Advanced Person-Centered (APC) Smart Home Care Model that is able to predict patient outcomes; and 2) evaluate the effectiveness of this model by assessing improvements in care and recovery for…
- Trial name
- NCT07419789
- Testing
- Advanced Person-Centered (APC) Smart Home Care Model
- Where
- 2 sites in Taiwan
- Volunteers
- 218 people
- Sponsor
- Chang Gung Memorial Hospital
Brain Injury, Hyponatremia
Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients
To assess the pharmacokinetic profile of tolvaptan in critically ill acute brain injury patients and to secondarily evaluate the clinical response and safety of tolvaptan in acute brain injured patients
- Trial name
- NCT02215148
- Testing
- Tolvaptan
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- University of North Carolina, Chapel Hill
CIN
Risk Factors,PREvention and OutComes for CI-AKI in PatientS undErgoing PCI at Intensive Care Unit(PRECISE-ICU)
A retrospective, observational study included all consecutively critically ill patients undergoing percutaneous coronary intervention(PCI) at intensive care unit (ICU) in Fujian Provincial Hospital from January 1st 2012 to…
- Trial name
- PRECISE-ICU (NCT03791606)
- Where
- China
- Volunteers
- 755 people
- Sponsor
- Kaiyang Lin
Brain Injury, Muscle Weakness
A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial
Intensive care unit (ICU) hospitalization saves lives but often does so at a high personal cost to ICU survivors who frequently experience significant cognitive impairment and an array of physical and functional disabilities that…
- Trial name
- RETURN (NCT00715494)
- Testing
- Cognitive, physical, and functional rehabilitation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University
Pressure Injuries, Skin Failure
Barrier Functions oF Skin in ICU: SKIN-BAR
This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration…
- Conditions
- Pressure Injuries, Skin Failure, Skin Abnormalities, Biophysical Parameters of Skin
- Trial name
- SKIN-BAR (NCT07560683)
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Koç University
Chronic Wounds
Evaluation of the Effectiveness of Daily Pulse Lavage Therapy in Chronic Wounds
This study evaluates the effectiveness of pulse lavage therapy in decreasing bacterial counts in chronic wounds.
- Trial name
- PLI2 (NCT01500746)
- Testing
- Pulse lavage treatment, Dressing changes
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwestern University