Clinical trials: Wound Closure Techniques
Wound Closure Techniques
Use of 2-octylcyanoacrylate (Dermabond) Versus 5-0 Fast Absorbing Gut During Cutaneous Wound Closure
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of linear cutaneous surgery wounds improves scar cosmesis compared to wound closure with 5-0 fast absorbing gut.
- Trial name
- NCT02547077
- Testing
- Wound Closure with 2-octylcyanoacrylate, Wound Closure with 5-0 Fast Absorbing Gut Sutures
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound Complication, Cardiac Surgery
Effectiveness of Topical Vancomycin in Reducing Sternal Wound Infections Post-Cardiac Surgery
Title: The Role of Vancomycin Powder in Reducing Sternal Wound Infections Following Cardiac Surgery: A Randomized Controlled Trial Introduction: Sternal wound infections (SWIs) are significant complications in cardiac surgery…
- Trial name
- NCT06651268
- Testing
- while Group B (vancomycin group, n=12) had vancomycin powder applied during closure. T
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Liaquat National Hospital & Medical College
Total Knee Replacement Closure, Wound Closure
A Comparative Study of Incision Closure Methods for Total Knee Replacement
The aim of the study is to compare incision closure techniques for total knee replacement using a combination of state-of-the-art sutures with tissue adhesives or staples in an effort to identify the best approach with respect to…
- Trial name
- NCT01088074
- Testing
- Histoacryl Tissue Adhesive, Dermabond, Staples
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Foundation for Southwest Orthopedic Research
Nasal Perforated Septum
New Method to Close Nasal Septal Perforation
The goal of this clinical trial is to investigate if a 3-dimensional fabricated nasal mesh works to close nasal septal perforations.
- Trial name
- NCT06439927
- Testing
- Polycaprolactone nasal mesh
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Helwan University
Wound Closure Techniques
Evaluation of Purse-String Closure Vs Second Intention
To compare healing time, scar size, aesthetic outcome, and complication rates following second intention healing or purse string closure of surgical wounds on the trunk or extremities.
- Trial name
- NCT02062866
- Testing
- Purse-String, Second Intent
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Surgical Wound, Knee Arthroplasty
Skin Closure in Prosthetic Joint Surgery: Comparative Evaluation of the "Barbed Sutures and Skin Glue" Technique (Cica-Pro)
The choice of skin closure (staples vs. monofilament sutures vs. barbed sutures/adhesive) is critical for wound healing quality in prosthetic surgery (hip and knee).
- Conditions
- Surgical Wound, Knee Arthroplasty, Hip Arthroplasty
- Trial name
- Cica-Pro (NCT07749495)
- Testing
- primary knee replacement, Primary hip replacement.
- Volunteers
- 400 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Androgenetic Alopecia
Split Wound Comparison of Trichophytic Closure Techniques for Donor Site in Hair Transplantation
This study aim to compare cosmetic results between 3 trichophytic closure techniques for donor site (the trimming of upper, lower and both edge of linear incision) in hair transplantation.
- Trial name
- NCT01655602
- Testing
- Trichophytic closure upper edge trimming, Trichophytic closure lower edge trimming, Trichophytic closure both edge trimming
- Where
- Thailand
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Surgical Wound, Tissue Adhesion
Skin Closure With Tissue Adhesives vs. Subcuticular Suture After Robotic Urogynecologic Procedures
To compare skin closure via subcuticular suture versus tissue adhesive (Dermabond) in urogynecological robotic surgeries. The primary outcome is incision cosmesis at the 12 week follow up visit.
- Trial name
- NCT03891004
- Testing
- Subcuticular Skin Closure, Tissue Adhesives
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- St. John Hospital & Medical Center
Wound Closure Techniques
Undermining During Cutaneous Wound Closure
The purpose of this study is to determine whether undermining during cutaneous surgery improves scar cosmesis compared to wound closure without undermining.
- Trial name
- NCT02289859
- Testing
- Wound Closure with Undermining, Wound Closure without Undermining
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Insufficient Bone Volume Prior to Implant Surgery
The Tooth Collar Technique
The aim of this study is to evaluate wound healing after the application of the Tooth Collar Technique (TCT) for bone augmentation in the upper or lower jaw.
- Trial name
- TCTechnique (NCT07753525)
- Testing
- Tooth Collar Technique
- Where
- 4 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Wound Healing Disturbance of
HIP-STITCH (Wound Recovery After THA)
This prospective randomised trial will investigate the effect of four different suturing techniques (Monocryl, Vicryl Rapide with Indermil skin glue, Dermabond Prineo, and Stryker Zip) on the amount of aberrant wound recovery…
- Trial name
- NCT06275776
- Testing
- Ethicon Monocryl Smooth Suture, Ethicon Vicryl Rapide Braided Suture, Flexifuze Indermil Topical Skin Adhesive
- Where
- Netherlands
- Volunteers
- 236 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus
Primary Closure vs Open Technique for Pilonidal Sinus
The purpose of this randomized controlled trial is to compare two commonly used surgical techniques for the treatment of pilonidal sinus disease: excision with primary closure and excision with open (lay-open) technique.
- Conditions
- Pilonidal Sinus Disease, Sacrococcygeal Pilonidal Sinus, Chronic Infected Sinus Tract, Post-surgical Wound Healing
- Trial name
- NCT07311707
- Testing
- Primary Suturing of Surgical Wound, Open Surgical Wound Management
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Stitch Technique
Abdominal Midline Wound Closure: Small Tissue Bites Versus Large Tissue Bites
The goal of this clinical trial is to learn whether a small stitch technique works better than a large bite technique for closing midline abdominal surgery wounds in adults having midline laparotomy surgery.
- Trial name
- NCT07621926
- Testing
- Small Stitch Closure Technique, Large Stitch Closure Technique
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Indus Hospital and Health Network
Colorectal Cancer
Interrupted 'Figure-of-X' Versus Continuous Suturing Technique for Abdominal Wall Closure in Colorectal Laparotomies
This prospective randomized comparative study aims to evaluate whether interrupted figure-of-X fascial closure reduces the incidence of burst abdomen compared with continuous suturing in patients undergoing open colorectal…
- Trial name
- X-CLOSURE (NCT07585344)
- Testing
- Interrupted 'Figure-of-X' Suturing Technique, CONTINUOUS AMSS CLOSURE
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Islamabad Medical and Dental College
Cesarean Section
Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
Women who have a cesarean delivery have a surgical incision on their abdomen (belly). The usual way to close this opening is with metal surgical staples.
- Trial name
- NCT00524511
- Testing
- Surgical skin staples, Dermabond
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Massachusetts, Worcester
Cesarean Section
Effect of Subcutaneous Tissue Closure on Wound Complications
Only a small number of research studies evaluated the impact of various subcutaneous tissue and skin closure methods at cesarean section.
- Trial name
- NCT03354078
- Testing
- interrupted sutures, continous sutures
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Fascial Closure
A New Abdomen Closure Technology Based on Component Separation: a Prospective Randomized Controlled Trial
At present, open-type abdominal surgery is routine access into the abdomen. Median incision is the common choice with open-type abdominal surgery. Layered abdomen-closing is often used at the end-time of the surgery.
- Trial name
- NCT03111134
- Testing
- modified component separation technique
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Xijing Hospital of Digestive Diseases
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Tonsillectomy, Children
Closure Method Study Following Tonsillectomy in Children
This is a children's study evaluating the effects of a tonsillectomy with tonsillar fossae closure compared to without closure of the operative wound.
- Trial name
- NCT00730340
- Testing
- Closure of the Tonsillar Fossa, Tonsillectomy with open fossa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma