Clinical trials: Wound Closure Techniques
Wound Heal, Wound of Skin
Aesthetic Outcome of Complex Linear Closure vs Second Intention Healing: Below the Knee
The purpose of this study is to determine whether complex linear closure vs second intention healing for cutaneous wounds below the knee affects esthetic outcomes (primary outcome).
- Trial name
- NCT05074212
- Testing
- Factorial Assignment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Davis
Flap Advancement, Primary Wound Closure
Flap Advancement Techniques in Ridge Augmentation
Different augmentation techniques has been proposed to resolve problem of hard and/or soft tissue ridge defects to enable dental implant placement.
- Trial name
- NCT03071523
- Testing
- coronally advanced lingual flap, periosteal releasing incision
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Cairo University
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Wound Closure Techniques
Use of 2-octylcyanoacrylate With Full-thickness Skin Grafts
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures.
- Trial name
- NCT02550574
- Testing
- Wound Closure with 2-octylcyanoacrylate, Wound Closure with 5-0 Vicryl Sutures
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Surgical Wound
Outcomes Comparing Different Methods of Skin Closure in Patients Undergoing Head and Neck Surgery.
When patients undergo neck dissection surgeries, the current standard of care is to close the skin layer with either metal staples, which are removed a few days post-operatively, or with sutures, which can be absorbable or…
- Trial name
- NCT02936063
- Testing
- Surgical staples, Subcuticular sutures
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Obesity, Pregnancy
Sutures vs. Staples Skin Closure After C-section in Obese Patients
This is a randomized prospective clinical trial designed to determine the wound complication rates for stainless steel staples versus subcuticular suture for skin closure in the obese parturient (BMI≥ 30kg/m2) undergoing cesarean…
- Trial name
- NCT01820221
- Testing
- Suture vs. staples closure method after c-section in obese women.
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Wound Closure Techniques
Closure Techniques and Scar Appearance
The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound sutures.
- Trial name
- NCT01352533
- Testing
- Running polypropylene closure, Tissue Adhesive (Derma-Bond), Subcuticular polyglactin-910 combined with tissue adhesive
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Cesarean Section, Wound Dehiscence
A New Technique for Uterine Incision Closure at The Time of Cesarean Section: Does it Make a Difference
The purpose of this study was to compare the short term operative outcomes of three different surgical techniques for uterine incision closure during cesarean section (CS).
- Trial name
- NCT04681378
- Testing
- double layer step up-step down technique
- Volunteers
- 120 people
- Sponsor
- Menoufia University
Total Knee Arthroplasty
Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty
This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion.
- Trial name
- NCT01924403
- Testing
- Staple Closure, Vertical Mattress Closure, Running Subcuticular Closure
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Wound Closure Techniques
Undermining During Cutaneous Wound Closure
The purpose of this study is to determine whether undermining during cutaneous surgery improves scar cosmesis compared to wound closure without undermining.
- Trial name
- NCT02289859
- Testing
- Wound Closure with Undermining, Wound Closure without Undermining
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound Complication
Comparing Wound Complications After Elective Abdominal Surgery Using Two Closure Techniques
Wound complications, increased hospital stays and post-operative morbidity are all common following abdominal surgery. Abdominal closure complications are strongly associated with the closure technique and material used.
- Trial name
- COFACTOR (NCT03527433)
- Testing
- New closure technique
- Where
- Lebanon
- Volunteers
- 274 people
- Sponsor
- American University of Beirut Medical Center
Injury of Abdominal Wall
Effect of Stitch Technique on the Occurrence of Incisional Hernia After Abdominal Wall Closure
The major long term complication of abdominal wall closure after a median laparotomy is the development of an incisional hernia.
- Trial name
- ESTOIH (NCT01965249)
- Testing
- Long stitch, Short Stitch
- Where
- 9 sites in Austria, Germany
- Volunteers
- 425 people
- Sponsor
- Aesculap AG
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Laparotomy, Incisional Hernia
Clinical Performance and Safety of Suture-TOOL
The goal of this single arm intervention study is to investigate the safety and performance of a suturing device for closure of the midline incision after open abdominal surgery.
- Conditions
- Laparotomy, Incisional Hernia, Wound Infection, Closure Technique
- Trial name
- NCT05695157
- Testing
- Suture-TOOL
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Suturion AB
Stoma Reversal Procedure
Comparison of Outcome of Purse-string Versus Conventional Linear Wound Closure Techniques in Patients Undergoing Stoma Reversal
To compare outcomes of purse-string skin closure and conventional linear skin closure techniques in patients undergoing stoma reversal
- Trial name
- NCT07605403
- Testing
- Purse-string wound closure, Conventional linear wound closure
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Children Hospital Faisalabad
Surgical Wound
RESPECT Trial - (Rapid Extravascular Sealing Via PercutanEous Collagen ImplanT)
The objective of this trial is to demonstrate the safety and effectiveness of the Cardiva VASCADE™ Vascular Closure System (VCS) in sealing femoral arterial access sites.
- Trial name
- RESPECT (NCT01297322)
- Testing
- Manual compression, Cardiva VASCADE™ Vascular Closure System
- Where
- 21 sites in United States, Australia
- Volunteers
- 420 people
- Sponsor
- Cardiva Medical, Inc.
Spinal Injuries
Wound Closure Techniques in Primary Spine Surgery
The Researchers are trying to determine if there is a difference in blood flow around a wound site when comparing three different types of wound closure techniques.
- Trial name
- NCT04396613
- Testing
- Closure technique
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Brow Ptosis, Surgical Wound
An Analysis of Dermabond vs. Non-Absorbable Sutures in Skin Closure for Brow Ptosis Procedures
The goal of this clinical trial is to compare Dermabond with non-absorbable sutures in skin closure after brow ptosis surgery. The main questions it aims to answer are: if Dermabond provides equivalent wound healing compared to…
- Trial name
- NCT05981443
- Testing
- Dermabond, Non-Absorbable Sutures
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Cody Blanchard