Clinical trials: Wound Healing
Hurler Syndrome, Fanconi Anemia
Bone Marrow Transplant With Abatacept for Non-Malignant Diseases
This is a single arm, phase I study to assess the tolerability of abatacept when combined with cyclosporine and mycophenolate mofetil as graft versus host disease prophylaxis in children undergoing unrelated hematopoietic stem…
- Conditions
- Hurler Syndrome, Fanconi Anemia, Glanzmann Thrombasthenia, Wiskott-Aldrich Syndrome
- Trial name
- NCT01917708
- Testing
- Abatacept
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Prolapse, Vaginal
Vaginal Native Tissues Repair for Pelvic Organ Prolapse
The aim of the study is to assess at one year the effectiveness of the vaginal patch plastron in comparison of the anterior colporraphy through a combined definition of success: anatomic and functional.
- Trial name
- TAPP (NCT03875989)
- Testing
- Anterior colporraphy, vaginal patch plastron
- Where
- 9 sites in France
- Volunteers
- 214 people
- Sponsor
- University Hospital, Limoges
Venous Leg Ulcer (VLU), Venous Hypertension Ulcers
Effect of Photobiomodulation on Healing of Venous Leg Ulcers
Venous leg ulcers are a significant public health problem because of their prolonged duration, high recurrence rates, and economic, social, and quality-of-life effects.
- Conditions
- Venous Leg Ulcer (VLU), Venous Hypertension Ulcers, Chronic Venous Insufficiency, Chronic Venous Disease
- Trial name
- NCT07123285
- Testing
- Photobiomodulation Therapy, Compression Therapy
- Where
- Brazil
- Volunteers
- 102 people
- Sponsor
- University of Nove de Julho
Werner's Syndrome
Descriptive Study of Recombinant Human Insulin-Like Growth Factor for Osteoporosis in Werner's Syndrome
OBJECTIVES: I. Assess the safety and efficacy of recombinant human insulin-like growth factor 1 in a patient with Werner's syndrome and osteoporosis.
- Trial name
- NCT00004815
- Testing
- growth hormone
- Volunteers
- 1 people
- Sponsor
- National Center for Research Resources (NCRR)
Parastomal Hernia
Risk Factors for Morbidity After Parastomal Hernia Repair
The Danish Ventral Hernia Database (DVHD) registers 37 different perioperative parameters. The aim of present study is to use large-scale data from DVHD to uncover risk factors for readmission, reoperation (any indication), death…
- Trial name
- PAHEREP (NCT01484743)
- Testing
- differences in surgical techniques
- Where
- Denmark
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Lower Eyelid Retraction
An Outcomes Assessment of the Utility of Belladerm Acellular Dermal Allograft in Ocular Lower Lid Retraction Repair
The purpose of this study is to Evaluate the efficacy and longevity of a Human-derived, non-cadaveric, acellular dermal implant (BellaDerm) as a posterior spacer graft in the correction of lower eyelid retraction, taking into…
- Trial name
- NCT02133495
- Testing
- Non Cadaveric Human Acellular Dermal Tissue
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- SGM Physician Research Consortium
Mitral Valve Insufficiency, Heart Failure
Carillon Mitral Contour System® for Reducing Functional Mitral Regurgitation
The objective of this prospective, multi-center, randomized, double-blind trial is to assess the safety and efficacy of the Carillon Mitral Contour System in treating functional mitral regurgitation (FMR) associated with heart…
- Trial name
- REDUCE FMR (NCT02325830)
- Testing
- Carillon Mitral Contour System
- Where
- 31 sites in Australia, Czechia and 6 more
- Volunteers
- 163 people
- Sponsor
- Cardiac Dimensions Pty Ltd
Pressure Ulcer
100% Whey Protein Based Diet In Enhancing Pressure Ulcer Healing.
This study seeks to evaluate if a 100% whey protein based diet enhances pressure ulcer healing.
- Trial name
- NCT03995407
- Testing
- Peptamen®, Usual Care
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- St Luke's Hospital, Singapore
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
we Study the Effect of Keeping the Patient Supine 2 Minutes After Spinal Anesthesia in Geriatric Groups
Delayed Supine Position Post-Spinal Compared With Immediate Supine Position in Geriatric Patients
Background: Geriatric patients undergoing femoral neck of fracture (FNOF) repair are highly susceptible to spinal anesthesia-induced hypotension.
- Trial name
- NCT07520695
- Testing
- 2 minutes setting post spinal anesthesia, immediate supine position
- Where
- Oman
- Volunteers
- 90 people
- Sponsor
- Sohar Hospital
Patients Receiving Direct Oral Anticoagulants
Effect of Tranexamic Acid-Modified Leukocyte- and Platelet-Rich Fibrin on Hemostasis and Wound Healing After Tooth Extraction in Patients Receiving Direct Oral Anticoagulants
This randomized split-mouth clinical study evaluated the effects of tranexamic acid-modified leukocyte- and platelet-rich fibrin (L-PRF) on hemostasis, postoperative pain, and soft-tissue wound healing after tooth extraction in…
- Trial name
- NCT07830875
- Testing
- Tranexamic Acid-Modified L-PRF, Absorbable Gelatin Sponge
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Cumhuriyet University
Persistent Postsurgical Pain
Investigate and Predict Aortic & Thoracic Surgery Persistenet Postsurgical Pain
This is an observational clinical study aiming to further the wider understanding of patients who develop persistent pain after Thoracoabdominal Aorta surgery, a surgical cohort who are disproportionately affected.
- Trial name
- ImPARTonPPP (NCT05369130)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Queen Mary University of London
Hypospadias Repair
Hemostasis During Hypospadias Surgery
A comparison between the two hemostatic methods of hypospadias repairing operation, in terms of early and mid-term (up to 6 months) failure rate (wound dehiscence and urethral stricture needing reoperation) between the two…
- Trial name
- NCT02268019
- Testing
- tourniquet application, epinephrine injection
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Thoracic Aortic Aneurysm, Thoracic Aortic Dissection
Impact of Right Atrial Occlusion on TEVAR Outcomes
Though the application of thoracic endovascular aortic repair (TEVAR) for treatment of aortic pathology is expanding, there remains a gap in the literature examining how intraoperative "reduction or elimination of aortic impulse"…
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aortic Dissection, Thoracic Aorta Abnormality
- Trial name
- NCT06786351
- Testing
- Right atrial balloon occlusion, Non right atrial balloon occlusion
- Volunteers
- 100 people
- Sponsor
- University of Calgary
Rotator Cuff Injury
Clinical & Radiological Assessment of Rotator Cuff Healing After Single Row Vs. Double Row Rotator Cuff Repair
This study is to analyse whether there is a difference in clinical and radiological outcomes between single row and double row repair techniques for the treatment of shoulder's rotator cuff tears.
- Trial name
- RCR (NCT03885856)
- Testing
- single row repair technique, double row repair technique
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University Hospital, Basel, Switzerland
Ventral Hernia
Laparoscopic Ventral Hernia Repair by Heavy Weight or Lighter Weight Mesh (COMPOSIX-trial)
1. General antibiotic prophylaxis: cefazoline (Cefacidal™) 2 gram iv administered 30 minutes before surgery 2. Laparoscopic surgery at least 5 cm overlap (mesh diameter should exceed hernia size by at least 10 cm) with or without…
- Trial name
- NCT00573105
- Testing
- Laparoscopic Ventral hernia repair by heavy weight mesh, Laparoscopic Ventral hernia repair by lighter weight mesh
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- University Hospital, Ghent
Impacted Third Molar, Postoperative Pain
Natural Enzyme Mouthwash After Third Molar Surgery
This clinical study investigates whether a natural enzyme-containing mouthwash (ORAL7®) can improve healing, pain and mouth opening after the surgical removal of impacted lower wisdom teeth (mandibular third molars), compared to…
- Conditions
- Impacted Third Molar, Postoperative Pain, Trismus, Wound Healing
- Trial name
- NCT07627945
- Testing
- ORAL7® Mouthwash, 0.2% Chlorhexidine Gluconate Mouthwash
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- MBD MARKETING SDN. BHD.
Ventral/Incisional Hernia Repairs
Trunk Strength Study
The purpose of this study is to measure abdominal wall strength both preoperatively and postoperatively in patients undergoing ventral/incisional hernia repairs.
- Trial name
- NCT01300936
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Kentucky
Non Cardiac Surgery
MET: REevaluation for Perioperative cArdIac Risk (MET-REPAIR)
Multicentre international prospective cohort study designed to answer the question: "In patients undergoing elevated risk noncardiac surgery, are METs estimated by questionnaire associated with perioperative major adverse…
- Trial name
- MET-REPAIR (NCT03016936)
- Where
- Germany
- Volunteers
- 15,000 people
- Sponsor
- European Society of Anaesthesiology
Pulp Necrosis
Lesion Sterilization and Tissue Repair Antibiotic Paste Versus Zinc Oxide and Eugenol Pulpectomy for Treatment of Primary Molars With Pulp Necrosis
The goal of this clinical trial is to compare the efficacy of lesion sterilization and tissue repair (LSTR) antibiotic paste versus zinc oxide eugenol (ZOE) pulpectomy for the treatment of primary molars with pulp necrosis in…
- Trial name
- LSTR (NCT07475364)
- Testing
- Group A - LSTR Therapy (CTZ Paste), Group B - ZOE Pulpectomy
- Volunteers
- 180 people
- Sponsor
- University of Faisalabad