Clinical trials: Wound Healing Disorder
Bladder Exstrophy-Epispadias Complex
Use of Platelet-Rich Fibrin in Bladder Exstrophy Repair
Bladder exstrophy-epispadias complex (BEEC) is a rare condition in which the bladder and surrounding structures do not form normally.
- Trial name
- PRF-BEEC (NCT07294612)
- Testing
- Autologous Platelet-Rich Fibrin, Standard Surgical Closure
- Where
- Uzbekistan
- Volunteers
- 20 people
- Sponsor
- National Children's Medical Center, Uzbekistan
Gingival Overgrowth
Comparison Between Laser, Synthetic Gel and Herbal Gel as Topical Agents After Gum Surgery
This study would be conducted to assess the effectiveness of low-level laser therapy, hyaluronic acid gel and herbal gel as adjunctive aids in the healing of gingivectomy wounds.
- Trial name
- CLSHGTAGS (NCT03569683)
- Testing
- External bevel gingivectomy, Diode laser Biostimulation, Hyaluronic acid (Gengigel) topical application.
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre
Pelvic Floor Disorders, Obstetric Trauma
Repair by Rehabilitation of Pelvic Floor Lesions After Vaginal Delivery Identified by Transperineal Ultrasound 3/4 D
SUMMARY: (Objective, design, scope of the study, subjects of study, instrumentation, results, conclusions) Objectives: To evaluate if the physiotherapy treatment in pelvic floor dysfunctions, identified by transperineal…
- Conditions
- Pelvic Floor Disorders, Obstetric Trauma, Physical Disorder, Physical Activity
- Trial name
- NCT03686956
- Testing
- Physiotherapy treatment
- Where
- Spain
- Volunteers
- 92 people
- Sponsor
- Hospital Universitario de Valme
Hair Loss/Baldness
Role of Bandage After FUE Hair Transplantation
The aim of this interventional study is to determine the role of bandage on the follicular donor sites on the scalp after FUE hair transplantation.
- Trial name
- NCT05984862
- Testing
- Bandage
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pak Medical and Diagnostic Center
Hematoma, Arthroplasty Complications
The Effect of Releasing the Tourniquet in Total Knee Replacement Before Closure on the Blood Loss , Joint Effusion , Hematoma Formation and Wound Complication
The study , observe the effect of releasing the Tourniquet in total knee replacement surgery before closure in comparison with releasing it after wound closure The effect was assessed by Hb drop post operative and Hematoma…
- Trial name
- NCT04810000
- Testing
- tourniquet
- Where
- Jordan
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Yazan Saleh Rajab Hammad
Periodontal Pocket, Periodontitis
Multicenter Study on the Use of a Collagen-based Hydrogel for the Treatment of 153 Periodontal Pockets in 38 Adults With Generalized Stage III Periodontitis
This is a prospective, observational, multicenter study designed to evaluate the real-world efficacy and safety of H42®, a collagen hydrogel, in the treatment of periodontal pockets.
- Trial name
- NCT07592377
- Testing
- H42® Collagen Hydrogel for the non-surgical treatment of periodontal pockets
- Where
- 2 sites in Italy
- Volunteers
- 38 people
- Sponsor
- Bioteck S.p.A.
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Wound, Knee Disease
Standard Dressing Versus Moist Dressing in the Course of the Postoperative Wound in Patients With Knee Prosthesis
The aim of the study is: to evaluate the efficacy of two post-operative dressings in the management of the surgical wounds in patients who received a knee prosthesis
- Trial name
- APOSIT-PTG (NCT04422119)
- Testing
- Multi-Foam dressing, Usual care
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Germans Trias i Pujol Hospital
Diabetic Foot Ulcers
Passive Training as a Treatment for Diabetic Foot Ulcers
Overall project design: This PhD project involves a randomized study on diabetic individuals with healing resistant wounds, comparing the effect of passive movement of the lower limb with standard treatment of diabetic wounds.
- Trial name
- NCT02785198
- Testing
- Passive knee extensor machine
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Diabetic Ulcers, Venous Leg Ulcer
PMCF Study of Debridement Pad
The design of the study is a clinical trial of Debridement Pad in subjects with superficial, chronic and acute wounds consisting of Diabetic ulcers, Arterial and Venous Leg ulcers, Pressure ulcers, Postoperative wounds healing by…
- Conditions
- Diabetic Ulcers, Venous Leg Ulcer, Arterial Leg Ulcer, Pressure Ulcer
- Trial name
- NCT07255937
- Testing
- Debridement Pad
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- Advanced Medical Solutions Ltd.
Ankle Sprains
Evaluation of the Recovery Experienced by Patients After an Ankle Sprain Treated in the Emergency Department of Nantes University Hospital
To evaluate the recovery experienced by patients with ankle sprains treated in the adult emergency department of Nantes University Hospital.
- Trial name
- ANKHEAL (NCT06657937)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Nantes University Hospital
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Diabetic Foot Ulcer, Diabetic Foot Ulcer (DFU)
The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer.
Primary outcome: To evaluate the efficacy of L-Carnitine supplementation on length and depth ulcer size Secondary outcome: To investigate the effect of L-Carnitine supplements on: 1. Vascular endothelial growth factor (VEGF) 2.
- Trial name
- NCT07768228
- Testing
- L- carnitine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Wound Infection, Wound Complication
Randomized Clinical Trial of Skin Closure With Staples Versus Suture
Women with gynecologic cancers are often obese and have other risk factors for post-operative wound separation. Data from obstetrics and orthopedic surgery literature have shown a decreased risk of wound separation and…
- Trial name
- NCT01977612
- Testing
- 4-0 monofilament suture, Stainless steel staples
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- Washington University School of Medicine
Diabetic Foot Ulcers (DFUs), Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing
This study is a prospective, randomized controlled trial designed to evaluate the effectiveness of Miro3D Wound Matrix plus Standard of Care (SOC) compared to SOC alone in treating Wagner Grade 1 diabetic foot ulcers (DFUs) and…
- Trial name
- STRIDDDE (NCT06939686)
- Testing
- Miro3D Wound Matrix, Standard of Care (SOC)
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Reprise Biomedical, Inc.
Rotator Cuff Tears, Rotator Cuff Injuries
Use of Nanoscaffold Augmentation in Rotator Cuff Repair: Clinical Outcome and Ultrasound Assessment of Healing Rates and Vascularity
The purpose is to assess Rotium, a novel nanoscaffold, impact on healing of a repaired rotator cuff and compare to a repair without Rotium.
- Conditions
- Rotator Cuff Tears, Rotator Cuff Injuries, Rotator Cuff Syndrome of Shoulder and Allied Disorders
- Trial name
- NCT04361266
- Testing
- Rotium nanoscaffold, Control arm rotator cuff repair
- Sponsor
- Joshua Szabo, MD
Surgical Site Infection, Pancreatic Neoplasms
Comparison Between Wound Vacuum Dressing and Standard Closure to Reduce Rates of Surgical Site Infections
Pancreaticoduodenectomy is associated with high perioperative morbidity, with surgical site infection (SSIs) being one of the most common complications.
- Conditions
- Surgical Site Infection, Pancreatic Neoplasms, Pancreatic Cancer, Chemotherapy Effects
- Trial name
- NCT03021668
- Testing
- Prevena Peel & Place Dressing, Standard Closure of the Surgical Incision
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johns Hopkins University
Inflammation of Mouth
Association of Periodontal Inflammation on Immune Response in Wound Healing
Subjects who are in need of extraction of a posterior tooth will be recruited for this study. Prior to extraction, periodontal clinical markers of inflammation, body-mass index and dental radiographs will be measured/taken.
- Trial name
- NCT04805320
- Testing
- Dental Extraction
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Venous Leg Ulcer, Venous Ulcer
Tissue Repair Gel in Venous Leg Ulcers (US)
The goal of this clinical trial is to learn if TR987 0.1% gel + Standard of Care works better than Standard of Care alone to treat Venous Leg Ulcers (VLUs).
- Conditions
- Venous Leg Ulcer, Venous Ulcer, Venous Stasis Ulcer, Venous Stasis
- Trial name
- TRIVIA (NCT06707090)
- Testing
- TR987 0.1% gel + Standard of Care, Standard of care
- Where
- 33 sites in United States
- Volunteers
- 312 people
- Sponsor
- TR Therapeutics
Epidermolysis Bullosa
The Efficacy of Trimethoprim in Wound Healing of Patients With Epidermolysis Bullosa
The purpose of this study is to assess the efficacy of trimethoprim in promoting wound healing and decreasing blister formation in patients with Epidermolysis Bullosa.
- Trial name
- NCT00380640
- Testing
- Trimethoprim
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- The Hospital for Sick Children