Clinical trials: Wound Healing Time, active
Hallux Valgus, Anesthesia
The Effects of Various Concentrations of Ropivacaine on the Onset and Duration of Ankle Blocks
Peripheral nerve blocks are essential in ensuring effective regional anesthesia and postoperative analgesia in forefoot surgery for hallux valgus repair, with or without minor concomitant toe procedures.
- Trial name
- ROADS (NCT06185608)
- Testing
- 0.25% ropivacaine, 0.5% ropivacaine, 1% ropivacaine
- Where
- Belgium
- Volunteers
- 174 people
- Sponsor
- Ziekenhuis Oost-Limburg
Diabetic Foot Ulcer (DFU)
Evaluating the Efficacy of FoundationDRS Solo in Addition to Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers
The goal of this clinical trial is to learn if using FoundationDRS Solo improves healing of chronic, non-healing foot ulcers in diabetic patients.
- Trial name
- NCT07290673
- Testing
- FoundationDRS Solo, Standard of Care
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Samaritan Biologics
Wound Healing
Comparison of Wound Healing Duration Between Vacuum-Assisted Closure (VAC) and Conventional Dressings
This randomized controlled trial will compare vacuum-assisted closure (VAC) therapy with conventional wound dressings for the treatment of open contaminated and dirty wounds.
- Trial name
- VAC-WOUND (NCT07832162)
- Testing
- Vacuum-Assisted Closure (VAC) Therapy Description:, Conventional Wound Dressing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Paraumbilical Hernia
Comparison of Extended Totally Extra-peritoneal Repair (ETEP) and Subcutaneous On-lay Endoscopic Approach (SCOLA) for Para-umbilical Hernia (PUH).
The goal of this clinical trial is to learn if one of two surgical techniques works better for treating paraumbilical hernias in adult men and women between 18 and 65 years old.
- Trial name
- NCT07434687
- Testing
- Extended Totally Extra Peritoneal Repair, Subcutaneous On-Lay Endoscopic Approach
- Where
- Pakistan
- Volunteers
- 86 people
- Sponsor
- King Edward Medical University
Hernia Inguinal
A Comparative Study Between TAPP and Lichtenstein Techniques for Inguinal Hernia Surgery
This study is comperative study between TAPP And Lichtenstein Techniques for Inguinal Hernia surgery.The Lichtenstein tension-free open hernioplasty involves placing a tailored polypropylene mesh over the inguinal canal defect…
- Trial name
- NCT07067281
- Testing
- Lichtenstein Tension-Free Mesh Hernioplasty, Laparoscopic Transabdominal Preperitoneal (TAPP) Repair
- Where
- India
- Volunteers
- 60 people
- Sponsor
- GSVM Medical College
Stress Urinary Incontinence, Vaginal Prolapse
BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)
The goal of this clinical trial is to learn if retropubic midurethral sling (RP-MUS) or bulkamide injection (PAHG) at the time of pelvic organ prolapse repair is better from the patient's perspective.
- Trial name
- BELIEVE (NCT06754046)
- Testing
- RP-MUS, PAHG
- Where
- United States
- Volunteers
- 476 people
- Sponsor
- University Hospitals Cleveland Medical Center
Myelomeningocele, Extubation Time
Operating Room Extubation and Postoperative Outcomes in Neonates With Meningomyelocele
Meningomyelocele is one of the most common neural tube defects requiring surgical repair in the neonatal period. Postoperative respiratory complications and the need for prolonged mechanical ventilation are important causes of…
- Conditions
- Myelomeningocele, Extubation Time, Neonatal
- Trial name
- MEROX (NCT07465055)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gaziantep City Hospital
Surgical Wound, Burns
A Prospective Study Using SupraSDRM® in Promoting Healing and Reducing the Time to Grafting of Full-thickness Wounds
This is a prospective, randomized, controlled, multi-center clinical study comparing SupraSDRM® to standard of care wound dressing, BTM, in the treatment of full-thickness wounds deemed not immediately suitable for definitive…
- Conditions
- Surgical Wound, Burns, Trauma Injury
- Trial name
- NCT06503406
- Testing
- SupraSDRM®, NovoSorb® BTM
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The Metis Foundation
Diabetic Foot Ulcer
Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.
The goal of this clinical trial is to learn if using perinatal tissue allografts improves healing of chronic, non-healing foot ulcers in diabetic patients.
- Trial name
- NCT06437028
- Testing
- Dual-layer perinatal tissue allograft, Three-layer fenestrated perinatal tissue allograft, Standard of care
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Samaritan Biologics
Burns Degree Second, Pediatric
Comparing How Burn Wounds and Scars Heal in Children Using Chitosan and Silver Dressings
Burns are among the most common types of trauma worldwide, ranking fourth after traffic accidents, falls, and violence, and account for an estimated 265,000 deaths annually (WHO).
- Trial name
- CHITAG (NCT06987981)
- Testing
- Chitosan-based dressing, Silver-based dressing
- Where
- Slovenia
- Volunteers
- 40 people
- Sponsor
- Miloš Potkonjak
Opioid Consumption, Postoperative, ESPB
Evaluation of the Postoperative Efficacy of Bilateral Lumbar Erector Spinae Plane Block (ESPB) in Patients Undergoing Lumbar Disc Herniation Repair Surgery
This prospective observational study aims to evaluate the efficacy of bilateral lumbar erector spinae plane (ESP) block in providing effective postoperative analgesia and its potential impact on early mobilization and length of…
- Conditions
- Opioid Consumption, Postoperative, ESPB, Postoperative Pain, Plane Blocks
- Trial name
- NCT07403734
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Immune-related Adverse Event, Neoadjuvant Therapy
Exploring the Treatment Duration of PD-1 Neoadjuvant Therapy in Stage II-III dMMR Rectal Cancer
This study aims to explore the optimal number of cycles of PD-1 monotherapy required at minimum, under the premise of ensuring pathological complete response (pCR) among patients with dMMR/MSI-H rectal cancer.
- Conditions
- Immune-related Adverse Event, Neoadjuvant Therapy, dMMR Colorectal Cancer
- Trial name
- NCT06613165
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Xijing Hospital
Neoplasms, Rectal
A Study of the Duration of Dostarlimab in Untreated Mismatch Repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H) Locally Advanced Rectal Cancer
This study is conducted in adults with rectal cancer that has a certain genetic type. The main goal is to find out whether a longer treatment period with dostarlimab can help more participants have a complete response to…
- Trial name
- DuraSTAR (NCT07740720)
- Testing
- Dostarlimab
- Volunteers
- 90 people
- Sponsor
- GlaxoSmithKline
Hernia, Inguinal, Inguinal Hernia
Pneumoperitoneum Duration and Bicarbonate Changes in Laparoscopic Hernia Surgery
The goal of this observational study is to learn how the length of pneumoperitoneum during laparoscopic inguinal hernia surgery may affect changes in blood bicarbonate levels.
- Trial name
- TAPPHCO3 (NCT07473583)
- Testing
- Laparoscopic Inguinal Hernia Repair (TAPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Haseki Training and Research Hospital
Wound Heal
Postoperative Wounds With Delayed Healing Risk of Clinical Trial Registration
this study aims to optimize the components of TIME CDST based on clinical practice and apply the optimized elements to the management of wounds with delayed healing risk after hip arthroplasty to identify and design the key steps…
- Trial name
- NCT06272097
- Testing
- Intervention program based on TIME-CDST tool led by wound specialist nurses, A routine wound care program
- Volunteers
- 492 people
- Sponsor
- Danni Feng
Mandibular Fracture Treatment
Inter Flex Three Dimensional Plate in Management of Mandibular Fracture RCT
The goal of this clinical trial is to learn if The use of a 3D-designed Inter-flex plate will achieve safe and desirable anatomical \& functional restoration with reduced operative time in mandibular fracture, Improvement of…
- Trial name
- NCT07263893
- Testing
- Group I :site with mandibular fracture will be treated with custom made Inter-flex three dimensional plate in site of mandibular fracture
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Hemorrhoid, Postoperative Pain
"Lignocaine vs GTN Ointment for Postoperative Pain After Hemorrhoidectomy")
This study is being conducted at the Department of General Surgery, King Edward Medical University, Lahore, Pakistan. The purpose of the trial is to compare the effectiveness of topical Lignocaine ointment versus topical Glyceryl…
- Trial name
- NCT07159334
- Testing
- Lignocaine Ointment, Glyceryl Trinitrate Ointment 0.2%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- King Edward Medical University
Diabetic Foot Ulcer
Diabetic Foot Ulcers: Shorter Treatment Period Using Custom Felt Relief?
The Surgical Outpatient Clinic at Molde Hospital has since 2015 offered specialized treatment for patients with diabetic foot ulcers. This treatment is given by an interdisciplinary diabetic foot ulcer team.
- Trial name
- NCT04058639
- Testing
- "custom felt relief", standard relief treatment
- Where
- Norway
- Volunteers
- 74 people
- Sponsor
- Helse Møre og Romsdal HF
Neoplasms, Colorectal, Solid Tumor
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Effectiveness of GSK4418959 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic characteristics that can make them more aggressive and challenging to treat.
- Conditions
- Neoplasms, Colorectal, Solid Tumor, Colon Cancer, Rectal Cancer
- Trial name
- SYLVER (NCT06710847)
- Testing
- GSK4418959, PD-1 inhibitor
- Where
- 22 sites in United States, Australia and 5 more
- Volunteers
- 14 people
- Sponsor
- GlaxoSmithKline
Retina; Detachment, Rhegmatogenous
Head Positioning After Retina Detachment Repair
This study aims to determine if one day post-operative prone head positioning can be as good as seven days post-operative prone head positioning in patients with retinal detachments with inferior retinal breaks after pars that…
- Trial name
- NCT03714503
- Testing
- Retina re-attachment repair using C3F8 gas tamponade
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Kansas Medical Center