Clinical trials: Wound Infections
Surgical Site Infection
Environmental Risk Factors of Mesh Infection After Abdominal Wall Hernia Repair
Mesh infection is the main complication in abdominal hernia repair. In case of infection, a conservative management of mesh is not always possible.
- Trial name
- NCT04174976
- Testing
- wall hernia repair
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Post Operative Wound Infection, Graft Uptake
Does Antibiotics Use During Surgery Help to Decrease Wound Infection and Increase Success After Ear Surgery in Children
This study assess whether there is any role of antibiotics to decrease wound infection and increase the success of surgery
- Conditions
- Post Operative Wound Infection, Graft Uptake, Myringoplasty
- Trial name
- NCT03700814
- Testing
- Co-amoxiclav
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University, Nepal
Infection
Disruption of Circadian Rhythm and Healthcare-related Infection in Patients With Severe Trauma
Circadian rhythms, which play crucial roles in physiology, are emerging as important regulators of specific immune functions. Hospitalization in intensive care unit leads to a deep impairment of circadian rhythm.
- Trial name
- NCT02307747
- Testing
- blood samples
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Surgical Site Infection, Vancomycin
Pharmacokinetics of Preoperative Vancomycin
A study of plasma and tissue vancomycin pharmacokinetics in pediatric surgical patients.
- Trial name
- NCT03453684
- Testing
- Administration of Vancomycin
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Colorado, Denver
Antibiotic Reaction, Wound Infection Superficial
Antibiotic Prophylaxis in Metabolic Bariatric Surgery
SUMMARY Rationale: Prophylactic antibiotics in laparoscopic surgeries, including Metabolic Bariatric Surgery (MBS), are routinely provided to reduce postoperative infections, especially at wound incision sites.
- Conditions
- Antibiotic Reaction, Wound Infection Superficial, Wound Infection Deep, Bariatric Surgery Candidate
- Trial name
- NCT06510452
- Testing
- 2000 mg of Cefazolin, 500 mg of Metronidazole IV, NACL 0.9% 100 ml
- Where
- 2 sites in Egypt, Netherlands
- Volunteers
- 3,352 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Surgical Site Infection
ChatGPT-4 for Surgical Site Infection Detection From Electronic Health Records After Colorectal Surgery.
Epidemiological surveillance is one of the eight core components of the World Health Organization Infection Prevention and Control Programmes. These include surveillance programmes for surgical site infection (SSI).
- Trial name
- Infect-IA-3 (NCT06626399)
- Testing
- Diagnosis of SSI
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Hospital de Granollers
Acute Lung Injury, Acute Respiratory Distress Syndrome
Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury
The purpose of the study is to identify the patients at high risk of developing Acute Lung Injury (ALI) at the time of hospital admission, and before intensive care unit admission.
- Trial name
- LIPS (NCT00980915)
- Where
- United States
- Volunteers
- 6,600 people
- Sponsor
- Mayo Clinic
Late Complication From Skin Graft, Infection of Skin Donor Site
Efficacy and Safety of Silk Fibroin With Bioactive Coating Layer Dressing
A split-thickness skin graft (STSG) is used for a large wounds or wounds that cannot be closed by primary and secondary wound closure.
- Conditions
- Late Complication From Skin Graft, Infection of Skin Donor Site, Impaired Wound Healing, Pain, Intractable
- Trial name
- NCT02091076
- Testing
- Silk fibroin with bioactive coating layer dressing, Bactigras wound dressing
- Where
- Thailand
- Volunteers
- 29 people
- Sponsor
- Chulalongkorn University
Tracheostomy Complication, Acquired Brain Injury
Cough Assessment in Patients With Severe Acquired Brain Injury
The cough assessment is fundamental in the weaning process as it gives information on the possibility to expel food and secretion out from the airways.
- Conditions
- Tracheostomy Complication, Acquired Brain Injury, Brain Injury, Pneumonia
- Trial name
- NCT02495558
- Testing
- Reflex Cough Test
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Laboratory-confirmed Bloodstream Infection, Central Line-associated Bloodstream Infections
Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections
Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality.
- Conditions
- Laboratory-confirmed Bloodstream Infection, Central Line-associated Bloodstream Infections, Mucosal Barrier Injury
- Trial name
- NCT02271243
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Boston Children's Hospital
MRSA Colonization
MRSA in a Trauma Population: Does Decolonization Prevent Infection?
All trauma patients admitted to certain Intensive Care Units (ICU) will have Methicillin-resistant Staphylococcus aureus (MRSA) nasal swabs performed to determine MRSA colonization status.
- Trial name
- NCT01820455
- Testing
- Chlorhexidine, Mupirocin, Soap baths, Lubricating Jelly
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Tennessee
Infection, Surgical Site
Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections
Maxillofacial space infections are among the most common infections encountered in oral and maxillofacial surgery and may progress to severe, life-threatening complications if not properly managed, making their treatment a…
- Trial name
- NCT07904143
- Testing
- Incision and drainage + Povidone-iodine irrigation, Incision and drainage + ozonated distilled
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Surgical Site Infection
Dressing Wear Time After Breast Augmentation With Prosthesis
This study was designed to determine whether the duration of dressing wear following augmentation mammaplasty influence skin colonization and eventually surgical site infections rates.
- Trial name
- NCT01553604
- Testing
- augmentation mammaplasty
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Daniela Francescato Veiga
Wound Infection, Surgical
Effect of the Negative Pressure Therapy Dressing Compared With Hydrogel Dressing.
The objective of the study is to measure the efficacy of the use of single-use portable negative pressure therapy (PICO ®) in the prevention of surgical wound infections (SSI) from cardiac surgery under extracorporeal circulation…
- Trial name
- PICO/2019 (NCT04265612)
- Testing
- Pico®" negative pressure dressing, Aquacel Surgical®" hydrogel dressing
- Where
- Spain
- Volunteers
- 253 people
- Sponsor
- Hospital Universitario de Canarias
Wound, Wound Infection
Plasma Activated Saline in Wound Treatment
This is a prospective, open-label, randomized, parallel controlled clinical trial. The purpose of this study is to understand the application value of plasma-activated normal saline in the treatment of different types of wounds.
- Conditions
- Wound, Wound Infection, Wound Heal
- Trial name
- NCT05924867
- Testing
- plasma activated saline, Routine nursing
- Where
- China
- Volunteers
- 162 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Abscess, Drain Abscess
Incision and Loop Drainage Utilizing a Novel Technique for Management of Cutaneous Abscess in an Adult Population
When using the rolled ring of a sterile glove as a loop drain in incision and loop drainage, is it superior to incision and drainage for treatment of a cutaneous abscess in 18 to 65 year-old patients presenting to the Emergency…
- Trial name
- NCT04241471
- Testing
- incision and loop drainage, traditional incision and drainage (I&D)
- Sponsor
- bryan malcolm
Wounds, Infections
Acid Base and Electrolytes Patterns in Drains Operational Wounds and Its Relation to Complications
Objective- The purpose of this study is to evaluate a connection between PH,PCO2,HCO3,PO2,Na,K,Glu and Lactate patterns in vacuum drains of different plastic operational wounds and its relation to infections and seroma formation.
- Conditions
- Wounds, Infections, Seroma
- Trial name
- NCT01454167
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Covid19, AKI
Efficacy and Safety of a Highly Selective Semipermeable Membrane (AN-69 Oxiris) vs (Standard AN-69) in COVID-19
Abstract Title: Randomized,open-label, controlled trial to evaluate efficacy and safety of a highly selective semipermeable membrane (AN69-Oxiris) in comparison with a selective semipermeable membrane ( standard AN69) in COVID-19…
- Trial name
- oXAKI-COV (NCT04597034)
- Testing
- AN69-Oxiris, AN69-Standard
- Where
- Mexico
- Volunteers
- 35 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Biochemical Markers ,NGAL,Cystatin c, Acute Kidneyinjury, Covid 19
Role of NGAL and Cystatin C in Prediction of Acute Kidney Injury Covid-19 Infection
Recent different biomarkers of acute kidney injury (AKI) have been manufactured by pharmaceutical industry. Studies proved that Neutrophil gelatinase-associated lipocalin (NGAL) and cystatin c are effective predictive biomarkers…
- Trial name
- NCT04603664
- Testing
- serum NGAL and cystatin c
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Septic Shock, Cirrhosis
Comparison of Angiotensin II to Standard Dose Vasopressors on Change in Arterial Elastance
A study to see whether a medication called Angiotensin II works better than the routinely used medication to raise blood pressure in people with liver disease who are experiencing a serious drop in blood pressure.
- Conditions
- Septic Shock, Cirrhosis, Vasodilatory Shock, Acute Kidney Injury
- Trial name
- Ang2 (NCT07568275)
- Testing
- Giapreza
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- The Cleveland Clinic
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