Clinical trials: Wound Infections
Fractures, Dislocations
Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation
We, the investigators at Queen's University, propose to conduct a randomized, double-blind, feasibility trial comparing low-dose ketamine versus fentanyl as adjuncts to Emergency Department procedural sedation with propofol.
- Conditions
- Fractures, Dislocations, Abscess, Anesthesia
- Trial name
- NCT00137085
- Testing
- ketamine
- Where
- Canada
- Volunteers
- 124 people
- Sponsor
- Queen's University
Surgical Site Infection
Irrisept Versus Standard of Care in the Prevention of Surgical Site Infections
The purpose of this study was to compare the rate of surgical site infections in patients randomized to Irrisept versus SoC, who had an open abdominal laparotomy for abdominal trauma or acute surgical abdomen.
- Trial name
- NCT02255487
- Testing
- IrriSept System, No Intervention - Standard of Care (SoC) only
- Where
- 17 sites in United States
- Volunteers
- 627 people
- Sponsor
- Irrimax Corporation
Posttraumatic Stress Disorder
Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers
Healthcare workers and COVID-19 patients may experience psychological distress consequent to the pandemic, and are at particularly elevated risk for experiencing posttraumatic stress disorder (PTSD), based on evidence from…
- Trial name
- NCT04887116
- Testing
- Virtual Reality Exposure Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Weill Medical College of Cornell University
Lacerations, Abscess
Effectiveness of Nitrous Oxide in the ED
This will be a randomized control trial. All patients for whom an emergency provider determines that abscess drainage or laceration repair are necessary will be considered for enrollment.
- Trial name
- NCT02703233
- Testing
- Nitrous Oxide, Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Surgical Site Infection (SSI)
Continuous Infusion Versus Intermittent IV Bolus of Cefazolin: Prevention of Surgical Site Infection During CABG Surgeries in Egyptian Patients.
A randomized controlled trial on adults who underwent coronary artery bypass grafting (CABG) surgery. To evaluate the effectiveness of intraoperative continuous infusion (CI) of cefazolin compared with intermittent (INT)…
- Trial name
- NCT07658378
- Testing
- Cefazolin 2 g Infusion, Cefazolin 2 GM Injection
- Volunteers
- 100 people
- Sponsor
- Helwan University
Surgical Site Infection, SCIP
Use of a Microbial Sealant to Reduce Surgical Site Infections.
Surgical site infections (SSI) are costly complications that may cause significant morbidity and increase the cost of care, particularly in colorectal surgery.
- Trial name
- Integuseal (NCT02241915)
- Testing
- Open Colorectal Surgery, Laparoscopic Surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Wound Healing, Wound Infection
Efficacy Study of a Bioelectric Dressing to Treat Wounds Caused by Curettage and Electrodesiccation
The purpose of this study is to determine whether a bioelectric wound dressing, a silver-coated dressing, or a silver-foam dressing are effective in the treatment of wounds resulting from curettage and electrodesiccation of skin…
- Trial name
- NCT01004055
- Testing
- Procellera™ Antimicrobial Wound Dressing, ACTICOAT™ Antimicrobial Barrier Dressing, Mepilex® Ag Silver Foam Dressing
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Vomaris Innovations
Colorectal Cancer, Surgery
The Effect of Wound Problems Wound Dressing in Patients With Colorectal Cancer Surgery
This study was conducted as a randomized controlled trial in order to determine the effect of prophylactic negative pressure wound therapy for the prevention of surgical site complications in high-risk colorectal cancer surgery.
- Conditions
- Colorectal Cancer, Surgery, Surgery--Complications, Surgical Site Infection
- Trial name
- NCT04735133
- Testing
- pNBYT
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- TC Erciyes University
Ventilator Associated Pneumonia, Infection
Probiotic Prophylaxis for Microbiome Modulation and VAP or Infections Prevention in Multitrauma Patients
Ventilator-associated pneumonia (VAP), is a type of pneumonia that develops more than 48 hours after endotracheal intubation, is common in intensive care units (ICUs).
- Conditions
- Ventilator Associated Pneumonia, Infection, Trauma
- Trial name
- NCT03074552
- Testing
- LactoLevure
- Where
- Greece
- Volunteers
- 112 people
- Sponsor
- Aristotle University Of Thessaloniki
Diabetic Foot Ulcer, Venous Leg Ulcer
Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION)
Evaluation of the efficacy (wound epithelialization and time to closure) and tolerance (emergence and nature of adverse event) of the new URGO AWC_008 and URGO AWC_022 dressings in local management of acute and chronic wounds at…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound Infection
- Trial name
- NCT05772507
- Testing
- URGO AWC_008 dressing or URGO AWC_022 dressing
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Laboratoires URGO
Posttraumatic Stress Disorder, Prolonged Grief Disorder
Tele-based Psychological Emotional Support for Informal CARegivers of COVID-19 Patients in Intensive Care
The experience of a loved one's stay in a COVID-19 intensive care unit (ICU), either intubated or on respiratory support, forces family caregivers (hereafter 'caregivers') to face core existential fears, such as uncertainty and…
- Conditions
- Posttraumatic Stress Disorder, Prolonged Grief Disorder, COVID
- Trial name
- CO-CarES (NCT04409821)
- Testing
- Tele-delivered psychological intervention
- Where
- 6 sites in Denmark
- Volunteers
- 40 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Septic Shock, Acute Kidney Injury
MCO Membrane Efficiency in Septic Shock Patients
This is a monocentre randomized pilot study. All patients received two consecutive RRT: CVVHD with MCO filter (Ultraflux® EMiC®2) and post-Continuous Veno-Venous Hemodiafiltration (CVVHDF) with HFF(AV1000S®) in a controlled…
- Trial name
- NCT04834921
- Testing
- Ultraflux® EMiC®2
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fiorenza Ferrari
Venous Ulcer, Infection
Restore Calcium Alginate Dressing, Silver vs Aquacel Ag in the Treatment of Critically Colonized Venous Leg Ulcers
Calcium alginate dressings with silver have been found to be safe and effective for use for leg ulcers. The primary objective is to compare Restore Calcium Alginate Dressing, Silver to AqualCel Ag Dressing on the following…
- Trial name
- NCT01396304
- Testing
- Restore Calcium Alginate Dressing, AquaCel Ag Wound Dressing
- Where
- 5 sites in United States
- Volunteers
- 19 people
- Sponsor
- Hollister Wound Care LLC
Septic Shock, Acute Kidney Injury
Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock
Sepsis is the most severe complication of infections. Sepsis-associated Acute kidney injury (AKI) is commonly encountered in critically ill patients and independently predicts poor outcome.
- Trial name
- DORESEP (NCT01473498)
- Testing
- Haemodynamic management
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Injuries
Has The COVID-19 Pandemic Affected Injury in Football?
This study aims to compare the injuries that occurred in the football players after the isolation and lack of training caused by New Coronavirus Disease (COVID-19), with the previous season, based on the example of a professional…
- Trial name
- NCT05262283
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Karadeniz Technical University
SURGICAL SITE INFECTION
Early Short-term Antibiotic Therapy in Penetrating Abdominal Trauma, 3 vs 7 Days
Abdominal penetrating trauma represents a frequent cause of consult into emergency rooms in Venezuela. Accidents and violence at Hospital "Miguel Perez Carreño" along april 2009 were represented by gunshots and stabbing wounds…
- Trial name
- NCT01203046
- Testing
- Ertapenem
- Volunteers
- 56 people
- Sponsor
- Silvia M. Pinango L.
Perceived Stress, Anxiety
Effects of Mobile App in House Staff Health and Well-being During COVID-19 Pandemic
Due to the COVID-19 global health pandemic, many people are likely experiencing increased stress. The well-being of physicians in training may be significantly impacted by this pandemic.
- Conditions
- Perceived Stress, Anxiety, Sleep Disturbance, Burnout
- Trial name
- NCT04374786
- Testing
- Calm Meditation App
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Skin Transplantation, Skin Grafting
Lower Extremity Graft Study (LEGS): A Multicentre Randomised Controlled Trial of Negative Pressure Wound Therapy Versus Conventional Dressings for Split-thickness Skin Grafts After Lower Leg Skin Tumour Excision
The goal of this clinical trial is to compare the effect of negative pressure wound therapy (NPWT) versus traditional dressings on the incidence of transplant infection in adult patients undergoing split-thickness skin grafting…
- Conditions
- Skin Transplantation, Skin Grafting, Split Thickness Skin Graft, Negative-Pressure Wound Therapy
- Trial name
- LEGS (NCT07040683)
- Testing
- Negative Pressure Wound Therapy (NPWT), Traditional Dressing
- Where
- Sweden
- Volunteers
- 232 people
- Sponsor
- Region Skane
Malaria, Sepsis
Optimal Fluid Management in Adult Severe Malaria
Optimal fluid therapy in severe falciparum malaria has not been well defined, especially in resource poor settings where access to mechanical ventilation is limited.
- Trial name
- DRIPICCO (NCT01936766)
- Where
- Bangladesh
- Volunteers
- 156 people
- Sponsor
- University of Oxford
Vascular Access Complication, Device Related Infection
Novel Antimicrobial Dressing in Peripheral Intravenous Catheters (PIVCs)
The goal of this clinical trial is to compare a chlorhexidine impregnated dressing for peripheral intravenous catheters (PIVCs) to the standard dressing currently used in general medical and surgical inpatient wards.
- Conditions
- Vascular Access Complication, Device Related Infection, Device Related Sepsis, Device Site Reactions
- Trial name
- ProP (NCT05741866)
- Testing
- Chlorhexidine gluconate impregnated bordered polyurethane dressing, Standard bordered polyurethane dressing
- Where
- 3 sites in Australia, France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Queensland
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.