Clinical trials: Wound Infections
Ear Infection Bacterial, Surgical Site Infection
Use of Preoperative and Postoperative Antimicrobial Treatment
In this study, patients undergoing ear surgery (cochlear implantation, stapedotomy, tympanoplasty) will be randomized to one of two antibiotic treatment groups.
- Conditions
- Ear Infection Bacterial, Surgical Site Infection, Antibiotic Side Effect
- Trial name
- NCT04707092
- Testing
- Antibiotic
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- Sunnybrook Health Sciences Centre
COVID19, ARDS
REgulatory T Cell infuSion fOr Lung Injury Due to COVID-19 PnEumonia
To assess the safety and efficacy of CK0802 in treatment of patients with COVID-19 induced moderate-to-severe PNA-ARDS.
- Trial name
- RESOLVE (NCT04468971)
- Testing
- CK0802
- Where
- 5 sites in United States
- Volunteers
- 45 people
- Sponsor
- Cellenkos, Inc.
Acquired Brain Injury, Comparative Effectiveness Research
Efficacy of EFA in Acquired Brain Injury
Acquired brain injury (ABI) is one of the biggest cause of death and disability in the world. Patients with ABI often have difficulties with swallow and breath.
- Conditions
- Acquired Brain Injury, Comparative Effectiveness Research, Lung Diseases, Obstructive
- Trial name
- NCT05993364
- Testing
- Free Aspire with Expiratory Flow Accelerator (EFA) technology, In-Exufflator Machine, Traditional respiratory treatment
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Staphylococcus Aureus, Wound Infection, Surgical
Staphylococcus Aureus Surgical Site Infection Multinational Epidemiology in Europe
This is a retrospective multinational, multicenter cohort study with a nested case-control. The study includes all surgical procedures performed at a participating site to prevent bias. Data will be assessed in two populations.
- Conditions
- Staphylococcus Aureus, Wound Infection, Surgical, Epidemiology
- Trial name
- SALT (NCT03353532)
- Where
- 14 sites in France, Germany and 3 more
- Volunteers
- 178,902 people
- Sponsor
- University of Cologne
Evaluate to Effects of Two Antiseptic Products and Showering
CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE
The study was planned to evaluate the effects of two most commonly used antiseptic products and showering on the healing process, such as wound healing and postoperative maternal comfort in cesarean section.
- Trial name
- NCT05953714
- Testing
- incision side cleaning with antiseptic products
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Sakarya University
Late Effects of Surgery, Staphylococcus Aureus
Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement.
- Conditions
- Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
- Trial name
- NCT00701636
- Testing
- daptomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Parotidectomy
Timing of Postoperative Drain Removal Following Parotidectomy - a Prospective Randomized Controlled Study
There is no standard of care of management following parotidectomies. Most practitioners however place a drain (usually a flat Davol closed suction drain/ Hemovac in the investigators institutions) in the wound bed at the end of…
- Trial name
- NCT01399021
- Testing
- Early Drain Removal, Late Drain Removal
- Where
- 4 sites in Canada
- Volunteers
- 400 people
- Sponsor
- University of British Columbia
Lower Leg Wound
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
A Pilot Study of the WoundWand™ Debridement Device on Infection Prevention
- Trial name
- WoundWand (NCT01924806)
- Testing
- WoundWand™ Debridement Device, Standard of Care sharp debridement
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 11 people
- Sponsor
- Smith & Nephew, Inc.
Ureaplasma Infections
Trial of Intravenous Azithromycin to Eradicate Ureaplasma Respiratory Tract Infection in Preterm Infants
The purpose of this study is to determine whether intravenous azithromycin is effective in eradicating Ureaplasma respiratory tract infection in preterm infants born at 24 to 28 weeks gestation.
- Trial name
- AZIPIII (NCT01778634)
- Testing
- Azithromycin
- Where
- 7 sites in United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Hearing Loss, Extreme
Protective Effect of N-acetylcysteine Against From Ototoxicity
Peritonitis is currently one of the leading complications of continuous ambulatory peritoneal dialysis (CAPD). Aminoglycosides and vancomycin are used in the treatment of CAPD peritonitis despite their potential risk for…
- Trial name
- NCT01271088
- Testing
- N-acetylcysteine
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Covid19, Respiratory Disease
COVID-19 Longitudinal Biomarkers in Lung Injury
Profile known and novel biomarkers in blood in COVID19 patients to characterize the host response to SARS-CoV-2 over time and in response to treatment. The investigators aim to: Better understand the disease.
- Conditions
- Covid19, Respiratory Disease, Critical Illness
- Trial name
- COLOBILI (NCT04747782)
- Testing
- no interventions performed. Just collecting data, blood samples and post-mortem biopsies.
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dr. Andrew Baker
Presence of Ileostomy
Need for Subcutaneous Wound Drains in Ileostomy Reversal
The purpose of this study is to find out whether the insertion of subcutaneous wound drains has an influence on postoperative hospital stay in ileostomy reversal.
- Trial name
- DRASTAR (NCT01050686)
- Testing
- insertion of subcutaneous wound drain, no insertion of subcutaneous wound drain
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- Charite University, Berlin, Germany
Acute Fracture Surgery, Alcohol Cessation Intervention
Alcohol Cessation Intervention in an Acute Surgical Setting
Hazardous alcohol intake is an independent risk factor for postoperative complications after major and minor operations, elective and emergency procedures for men and women.
- Conditions
- Acute Fracture Surgery, Alcohol Cessation Intervention, Postoperative Complications, Infection
- Trial name
- NCT00986791
- Testing
- GSP-A
- Where
- 3 sites in Denmark
- Volunteers
- 70 people
- Sponsor
- Bispebjerg Hospital
Stress Disorders, Post-Traumatic, Stress Related Disorder
Mindfulness-SOS: Stress Reduction for Refugees
The COVID-19 pandemic crisis is associated with a wide range of stressors for the general population. For forcibly displaced persons (FDPs), the turmoil of this crisis is magnified significantly, and elevated pre-existing…
- Trial name
- NCT04761510
- Testing
- Mindfulness-SOS for Refugees
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Geriatric Presentation of Urinary Tract Infection, Acute Kidney Injury
Intraoperative NGAL Level in Geriatric Patients Undergoing Laparotomy
The aim of this study is to detect early renal dysfunction that may occur during the surgical procedure in geriatric patients who will undergo laparotomy surgery.
- Trial name
- NCT05030727
- Testing
- record of pNGAL
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Surgical Site Infection
Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection
Surgical site infections (SSI) are the most common healthcare-associated infections and sources of morbidity and over-mortality.
- Trial name
- NCT06108791
- Testing
- FIO2=0.8, FIO2=0.33
- Where
- Egypt
- Volunteers
- 146 people
- Sponsor
- Assiut University
Covid19
COVID-19 Soliris Expanded Access Protocol
This protocol provides participants with COVID-19 access to Soliris.
- Trial name
- NCT04802083
- Testing
- Eculizumab
- Sponsor
- Alexion Pharmaceuticals, Inc.
Thyroid Diseases, Wound Healing
Safety and Efficacy of NTP in Thyroid Surgery: Pilot Study on Morbidity Prevention and Adjuvant Oncological Control
The goal of this clinical trial is to evaluate the therapeutic efficacy and safety of non-thermal plasma (NTP) as an adjuvant treatment for surgical bed decontamination and accelerated tissue repair in patients undergoing total…
- Conditions
- Thyroid Diseases, Wound Healing, Thyroidectomy, Surgical Wound Infection
- Trial name
- NCT07382973
- Testing
- Atmospheric Pressure Non-Thermal Plasma, Standard Surgical Wound Care Protocol
- Where
- Mexico
- Volunteers
- 26 people
- Sponsor
- National Institute of Nuclear Research - Mexico
Wound Infection
To Assess Use of Vancomycin Powder in Craniotomy on Wound Infection Rates
Surgical site infection (SSI) after craniotomy is a major cause of morbidity and mortality besides its major health care cost. In each hospital, all measures are taken to decrease SSI.
- Trial name
- NCT04917627
- Testing
- Vancomycin
- Where
- Qatar
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Hamad General Hospital
Surgical Site Infection
AO Multicenter Intervention Trial for Prevention of Surgical Site Infection
This study is designed to collect data from 8,476 fracture patients during a pre-and post-intervention phases of two years length each. The intervention consists on the implementation of the AOT SSI Prevention Bundle. D
- Trial name
- AOPOSSI (NCT03380273)
- Testing
- Implementation of the AO Trauma SSI Prevention Bundle
- Where
- 14 sites in United States, Argentina and 4 more
- Volunteers
- 222 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
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