Clinical trials: Wound Leg
Hip Injuries, Fractures, Hip
Mitigation of Major Hip Injury Due to Fall With a Smart Belt
Multi-center, comparative, non-significant risk adaptive study with retrospective controls. After providing informed consent and being screened for eligibility, intervention subjects will be prescribed and provided an…
- Conditions
- Hip Injuries, Fractures, Hip, Fall Injury, Fall Risk
- Trial name
- NCT05245097
- Testing
- Tango Belt, Standard of Care (SOC)
- Where
- 10 sites in United States
- Volunteers
- 471 people
- Sponsor
- ActiveProtective Technologies, Inc
Diabetes, Wound Infection
Tissue Penetration of Ceftolozane/Tazobactam in Diabetic Patients With Lower Limb Infections
This study will determine the tissue penetration of ceftolozane/tazobactam (Zerbaxa, Merck \& Co.), a novel β-lactam/β-lactamase combination antibiotic, into the extracellular, interstitial fluid of soft tissue in diabetic…
- Conditions
- Diabetes, Wound Infection, Healthy Volunteers
- Trial name
- NCT02620774
- Testing
- Ceftolozane/tazobactam, Microdialysis Catheter Insertion
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Tibial Meniscus Injuries, Tibial Meniscus Tears
Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury
The purpose of this study is to determine if extended-release triamcinolone acetonide treatment alters the progressive changes in bone shape previously demonstrated after anterior cruciate ligament (ACL) reconstruction with…
- Conditions
- Tibial Meniscus Injuries, Tibial Meniscus Tears, Tibial Meniscus, Torn, Anterior Cruciate Ligament Tear
- Trial name
- SLAM (NCT04331002)
- Testing
- Zilretta
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Austin V Stone
ACL Injury
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
Females who participate in cutting and landing sports suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate than males participating in the same high-risk sports.
- Trial name
- NCT01034527
- Testing
- Neuromuscular Training
- Where
- United States
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ACL Injury
Clinical Outcomes of ACL Reconstruction Augmented by an Injectable Osteoconductive/Osteoinductive Compound
The goal of this study is to determine whether the use of injectable osteoinductive/osteoconductive compounds (OOC) during Anterior Cruciate Ligament (ACL) reconstructive surgery, combined with an accelerated rehabilitation…
- Trial name
- NCT04993339
- Testing
- OOC
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Foot Injuries and Disorders
Ankle Foot Orthosis Comparative Effect
The proposed effort is designed to support evidence-based practice and optimal care by evaluating how the form, fit and function of two commercially available carbon fiber custom fit braces (Orthoses) influences outcomes…
- Trial name
- AFOCE (NCT03901053)
- Testing
- Reaktiv AFO, PhatBrace AFO
- Where
- 3 sites in United States
- Volunteers
- 54 people
- Sponsor
- Jason Wilken
Inguinal Hernia, Pelvic Fracture
Corona Mortis in Patients Undergoing TEP for Inguinal Hernia
This study aim to describe the presence, type and size of Corona mortis (CMOR) in patients undergoing total extraperitoneal (TEP) inguinal hernia repair procedures.
- Conditions
- Inguinal Hernia, Pelvic Fracture, Acetabular Fracture, Bleeding
- Trial name
- NCT04303442
- Testing
- TEP
- Where
- Bulgaria
- Volunteers
- 300 people
- Sponsor
- Sofia Med Hospital
Femur Fracture, Femur Fracture Intertrochanteric
THP Hip Fracture Plating System Study
The objective of this study is to systematically document the clinical outcomes of THP Hip Fracture Plating System when used to treat intracapsular and intertrochanteric fractures.
- Conditions
- Femur Fracture, Femur Fracture Intertrochanteric, Garden Grade I Subcapital Fracture of Femoral Neck, Garden Grade II Subcapital Fracture of Femoral Neck
- Trial name
- THP (NCT03870477)
- Testing
- THP Hip Fracture Plating System with telescoping lag screws
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Zimmer Biomet
Patella Dislocation, Patella Dislocation Recurrent
INDividualised EXercise for Kneecap Dislocations
This study is a feasibility study. It will assess areas of uncertainty relating to the implementation of an individualised exercise programme for patients with a recent kneecap dislocation.
- Trial name
- INDEX-KD (NCT03798483)
- Testing
- Individualised exercise
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- City, University of London
Femoral Fractures
Effects of Liposomal Bupivacaine for Acute Pain in Hip and Femur Fractures
This is an investigator-initiated, single-center, randomized, patient blinded, controlled trial. The purpose of this study is to compare the effect of a fascia iliaca compartment block (FICB) using 0.2% ropivacaine vs.
- Trial name
- NCT02679560
- Testing
- Liposomal Bupivacaine, Ropivacaine HCL
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Ian Elliott Brown
Lower Extremity Wound Infected, Venous Stasis Ulcers
V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds
This study would like to determine if using negative pressure wound therapy with an instillation of .125% Dakins is more effective than using negative pressure wound therapy alone on biofilm removal, disruption and elimination in…
- Trial name
- NCT02009501
- Testing
- VAC VeraFlo with Dakins Instillation, VAC Ulta Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Venous Leg Ulcer
Trial on the Efficacy of Prontosan Wound Irrigation Solution and Prontosan Wound Gel
The primary objective of the study is to evaluate the efficacy of Prontosan® Wound Irrigation Solution and Prontosan® Wound Gel in the treatment of hard-to heal venous leg ulcers compared to control saline irrigation solution and…
- Trial name
- NCT01153633
- Testing
- Prontosan Wound Irrigation Solution and Prontosan Wound Gel
- Where
- United Kingdom
- Volunteers
- 34 people
- Sponsor
- B. Braun Ltd. Centre of Excellence Infection Control
Femur Neck Fracture
Second Study of the Effect of Teriparatide on Hip Fracture Healing
The purpose of this study is to see whether teriparatide, given for 6 months versus placebo, will improve the healing of hip (femoral neck) fractures that are repaired during surgery using certain types of orthopedic screws.
- Trial name
- NCT01473602
- Testing
- Teriparatide, Calcium supplementation, Vitamin D supplementation
- Where
- 75 sites in United States, Belgium and 12 more
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company
Hip Fractures
Acute Hip Fracture Study in Patients 65 Years or Greater
This is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to investigate the safety, tolerability, and efficacy of VK5211 after 12 weeks of treatment.
- Trial name
- NCT02578095
- Testing
- VK5211
- Where
- 21 sites in United States, Hungary and 2 more
- Volunteers
- 108 people
- Sponsor
- Viking Therapeutics, Inc.
Amputation Wound, Traumatic Amputation of Toe
Longitudinal Study of Weight Change Following Lower Limb Amputation
The purpose of this study is to assess weight change in a population of Veterans with amputations. Little is known about the how weight changes following an amputation.
- Conditions
- Amputation Wound, Traumatic Amputation of Toe, Dysvascular Amputation of Lower Limb
- Trial name
- NCT00932399
- Where
- United States
- Volunteers
- 4,549 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabetic Foot, Diabetic Foot Ulcer
Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers
The feasibility phase of the study was conducted to assess the feasibility of a novel, patient-centered, remote wound management system.
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Wound; Foot, Wound Leg
- Trial name
- NCT05579743
- Testing
- Remote wound monitoring technology
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Johns Hopkins University
Anterior Cruciate Ligament Rupture
Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction
This study will consist of 80 patients ages 18 to 50 at the Emory Orthopaedic and Spine Center who are undergoing Anterior Cruciate Ligament (ACL) reconstruction with a quadriceps tendon autograft or bone patellar tendon bone…
- Trial name
- NCT02189317
- Testing
- Exparel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Ulcer, Leg, Heal Wound
Wound Dressing With Moisture Sensor
Explorative study of function of a moisture sensor on top of a superabsorbent wound dressing on exuding leg ulcers.
- Trial name
- NCT03468816
- Testing
- Sensor activation (on DryMax Extra Soft)
- Where
- 2 sites in Sweden
- Volunteers
- 5 people
- Sponsor
- Vårdcentralen Åby
Diabetic Foot Ulcer of Neuropathic Origin
The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Northern Europe The TRANS-North Study
Trafermin is a recombinant human basic fibroblast growth factor (bFGF; original development code, KCB-1), which is manufactured by genetic engineering using Escherichia coli by Kaken Pharmaceutical Co., Ltd. (Tokyo, Japan).
- Trial name
- TRANS-North (NCT01217476)
- Testing
- Trafermin 0.01% spray
- Where
- 37 sites in Belgium, Bulgaria and 8 more
- Volunteers
- 207 people
- Sponsor
- Olympus Biotech Corporation
Sickle Cell Leg Ulcer
Test of the Safety, Effectiveness, & Acceptability of An Improvised Dressing for Sickle Cell Leg Ulcers in the Tropics
One in 300 Jamaicans have HbSS sickle cell disease, and of these, up to 70% will suffer from sickle cell leg ulcers (SCLUs). Of these, 24% will have a chronic SCLU (one lasting longer than 6 months).
- Trial name
- SCLUJamaica (NCT04479618)
- Testing
- Usual Practice, Improvised dressing, Advanced dressing
- Where
- Jamaica
- Volunteers
- 48 people
- Sponsor
- Benskin, Linda, PhD, RN, SRN (Ghana), CWCN, CWS, DAPWCA