Clinical trials: Wound Surgical
Appendicitis, Cholelithiasis
Single Incision Laparoscopy
Laparoscopic surgery being performed with only one small incision via the umbilicus (belly button).
- Conditions
- Appendicitis, Cholelithiasis, Malignant Hypertension
- Trial name
- SIL (NCT00616616)
- Testing
- single incision laparoscopic surgery
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Ischemic Heart Disease
Effect of Remote Preconditioning in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery
In recent several clinical trials, remote preconditioning showed very powerful myocardial protection. However, the myocardial protective effect by remote preconditioning was not evaluated on the patients undergoing off pump…
- Trial name
- NCT00889811
- Testing
- remote ischemic preconditioning
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Postoperative Delirium
Association of Plasma Biomarkers for Neurological Injury and Postoperative Delirium After Cardiac Surgery
Delirium is one of the most common complications after cardiac surgeries, incidence of which is 20~70%. Causes and pathophysiology of delirium has not been elucidated yet, however, inflammatory response of the nervous system…
- Trial name
- NCT04194411
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Yonsei University
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Wrist Fracture
Axillary Block in Association With Analgesic Truncal Blocks at the Elbow for Wrist Surgery.
Fractures of the forearm bones that occur around the wrist are common in the elderly. Standard anesthesia for its surgical treatment is regional anesthesia (RA): supraclavicular block, infraclavicular block or axillary block…
- Trial name
- BAXASSO (NCT04046744)
- Testing
- Axillary brachial plexus block with a long-acting local anesthetic, Axillary brachial plexus block with a short-acting local anesthetic + Analgesic block at the elbow with a long-acting local anesthetic, Ropivacaine
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- CMC Ambroise Paré
Complication of Surgical Procedure, Acute Respiratory Failure, Adult
Prospective Evaluation of a RIsk Score for Postoperative Pulmonary COmPlications in Europe
Prospective Evaluation of a RIsk Score for postoperative pulmonary COmPlications in Europe (PERISCOPE) is a multi-centre, international observational study of a random-sample cohort of patients undergoing a nonobstetric…
- Conditions
- Complication of Surgical Procedure, Acute Respiratory Failure, Adult, Postoperative Respiratory Complications, Pulmonary Failure
- Trial name
- PERISCOPE (NCT01346709)
- Where
- 63 sites in Albania, Belgium and 19 more
- Volunteers
- 5,450 people
- Sponsor
- European Society of Anaesthesiology
Prevention of Surgical Site Infections
Tumescent Antibiotic Delivery Pharmacokinetics
Tumescent Antibiotic Delivery (TAD) is a technique for improving the prevention of surgical site infections (SSI). TAD involves the subcutaneous infiltration of tumescent local anesthesia (TLA) containing water soluble…
- Trial name
- NCT01046981
- Testing
- Tumescent Antibiotic Delivery of cefazolin with or without metronidazole, Intravenous Antibiotic Delivery
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
Surgical Wound Infection
Post Cesarian Section Wound Infections At Emergency Room
The goal of this observational study is to compare the incidence of post-cesarean section wound infections between emergency and elective cesarean deliveries at El-hussien Hospital.
- Trial name
- NCT06491381
- Testing
- Cesarean delivery
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Al-Azhar University
Myopia, High Myopia
Clinical Results of Small Incision Lenticule Extraction (SMILE) for the Correction of High Myopia
Small Incision Lenticule Extraction (SMILE) was introduced in 2011 using the VISUMAX femtosecond laser (Carl Zeiss Meditec, Jena, Germany). It is designed for correction of myopia and myopic astigmatism.
- Trial name
- NCT04110067
- Testing
- Small Incision Lenticule Extraction (SMILE) with Visumax (Carl Zeiss Meditec, Jena)
- Where
- Germany
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Suphi Taneri
Aortic Occlusion
Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery
Aortic occlusion (AO) for trauma has traditionally been accomplished by supra-diaphragmatic clamping of the descending thoracic aorta via emergent thoracotomy or as an initial step during laparotomy.
- Trial name
- NCT05263765
- Testing
- utilization of AO in the acute resuscitation of trauma and acute care surgery patients in shock.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Methodist Health System
Periapical Diseases, Endodontic Overfill
Post-Operative Evaluation of Endodontic Microsurgeries Done Using a Piezoelectric Ultrasonic Technique: An in Vivo Study
The aim of the study was to evaluate the effect of Piezosurgery and Trephine bur as cutting tools on post-operative sequelae including pain and swelling following guided endodontic microsurgeries.
- Conditions
- Periapical Diseases, Endodontic Overfill, Healing Surgical Wounds
- Trial name
- NCT05863728
- Testing
- Piezosurgery assisted group, Trephine Bur assisted group
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Distal Bicep Tendon Rupture
Trial Comparing Single Versus Double Incision to Repair Distal Bicep Tendon Ruptures
The purpose of this study to to determine whether a single incision technique or a double incision technique is more effective in the surgical treatment of distal bicep tendon ruptures.
- Trial name
- BRT (NCT01322828)
- Testing
- Distal bicep tendon reconstruction
- Where
- 2 sites in Canada
- Volunteers
- 92 people
- Sponsor
- Hand and Upper Limb Clinic, Canada
Hallux Valgus
Continuous Wound Infiltration After Hallux Valgus Surgery
The aim of this study is to investigate the effect of continuous wound infiltration with ropivacaine in comparison to standard pain management after elective distal metatarsal osteotomy for postoperative pain control.
- Trial name
- CWI-HVS (NCT02182999)
- Testing
- Wound infiltration catheter, NaCl 0.9%, Ropivacaine 0.2%
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University Innsbruck
Surgical Site Infection
ChatGPT-4 for Surgical Site Infection Detection From Electronic Health Records After Colorectal Surgery.
Epidemiological surveillance is one of the eight core components of the World Health Organization Infection Prevention and Control Programmes. These include surveillance programmes for surgical site infection (SSI).
- Trial name
- Infect-IA-3 (NCT06626399)
- Testing
- Diagnosis of SSI
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Hospital de Granollers
Child
The Effect of Supporting the Incision Site With Toys During Mobilization in Children Aged 4-10 Years Undergoing Abdominal Surgery
Aim: The aim of this study is to determine the effect of supporting the wound area with a toy during mobilization on pain and fear in children undergoing abdominal surgery. Method: The study was a randomised controlled trial.
- Trial name
- NCT07428421
- Testing
- Toy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Mucogingival Defects
Resveratrol-Based Gel Application in a Palatal Wound Following Free Gingival Graft Surgery
Aim of the study to compare the effect of Resveratrol- Based gel versus 0.2% Hyaluronic acid gel applied to the palatal donor site and acrylic resin stent only in post-operative pain reduction after free gingival graft harvesting.
- Trial name
- NCT06521333
- Testing
- Resveratrol-Based gel, Hyaluronic acid gel 0.2%, Stent
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lung Injury, Pulmonary Complication
Intra-operative Fraction of Inspired Oxygen and Lung Injury in Coronary Artery Bypass Grafting Surgery
This study is a prospective observer blinded, central randomization controlled, multi-center clinical trial to assess the relationship between intraoperative FiO2 and postoperative pulmonary complications with lung injury.
- Trial name
- NCT04115501
- Testing
- Fraction of Inspired Oxygen
- Where
- United States
- Sponsor
- University of Louisville
Pneumothorax
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural…
- Trial name
- LUSvsCXR (NCT06022081)
- Testing
- Lung ultrasound to detect pneumothorax.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Myocardial Injury, Non-cardiac Surgery
Hemodynamics and Myocardial Injury After Non-cardiac Surgery
The incidence of myocardial injury after non-cardiac surgery (MINS) is approximately 12-15% and is associated with an increased risk of 30-day mortality, 1-year mortality, and 2-year major vascular events.
- Conditions
- Myocardial Injury, Non-cardiac Surgery, Complication,Postoperative, High-sensitivity Troponin
- Trial name
- MINS (NCT05188001)
- Testing
- Not an Interventional Study
- Where
- Canada
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York