Clinical trials: Wound of Knee
ACL Tear, Post Operative Pain
Impact of Opioid Avoidance Protocol for ACL Reconstruction
This is a prospective, quasi-experimental, cohort study comparing patients treated with one of two postoperative pain management protocols.
- Trial name
- NCT06340932
- Testing
- Iovera, Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Matthew Varacallo
Anterior Cruciate Ligament, Injury
Comparison of Doubled Quadrupled Versus Quadrupled Allograft Tissue Constructs for Anterior Cruciate Ligament (ACL) Reconstruction
The purpose of this study is to compare two different soft tissue allografts, double bundle tibialis anterior allograft or quadruple bundle hamstring allograft, used in repairing a torn anterior cruciate ligament (ACL) of the…
- Trial name
- NCT01148784
- Testing
- ACL reconstruction
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Oregon Health and Science University
Meniscal Tears
Effects of Pulsed Electromagnetic Field Therapy on Meniscal Healing, Symptom Relief, and Knee Function
The goal of this clinical trial is to learn if pulsed electromagnetic field (PEMF) combined with home exercise improves healing and function in adults with meniscus tears. The main questions it aims to answer are: 1.
- Trial name
- NCT07117929
- Testing
- Active PEMF, Exercise
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Anterior Cruciate Ligament Injuries
A Reliability and Validity Study of Urdu Version of Lysholm Knee Scoring Scale.
The study will be intended to translate and check if the Urdu Version of Lysholm Knee Scoring Scale is reliable and valid in the Pakistani patients with anterior cruciate ligament injuries.
- Trial name
- NCT05207553
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
ACL Injury, Post Operative Pain
iPACK for Post-op Pain Following ACL Reconstruction
This study will consist of patients 12 years and older undergoing ACL reconstruction using a quadriceps or bone-patella tendon bone (BTB) graft.
- Trial name
- NCT05498870
- Testing
- Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Medical University of South Carolina
Core Strength, Knee Stability
Influence of Abdominal Muscle Function on Knee Stability for Injury Prevention
The goal of this clinical trial is to learn whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35.
- Trial name
- NCT07499973
- Testing
- Core Stabilization Training Program
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- European University of Madrid
Osteoarthritis, Knee, Patellofemoral Knee Arthroplasty
Study of Knee Replacements for Patellofemoral Osteoarthritis
This is a randomized comparison of PFA and TKR in treatment of isolated patellofemoral osteoarthritis.
- Trial name
- PFA/TKR (NCT01326156)
- Testing
- Knee arthroplasty
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Osteoarthritis, Pain, Postoperative
Liposomal Bupivacaine Versus Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Total Knee Arthroplasty
The purpose of this study is to compare the efficacy and duration of pain relief after total knee arthroplasty provided by a single injection of liposomal bupivacaine (EXPAREL®) versus standard bupivacaine with an adjuvant…
- Trial name
- NCT02624856
- Testing
- Liposomal bupivacaine, Bupivacaine plus dexamethasone
- Where
- United States
- Sponsor
- Albany Medical College
ACL Injury
Dietary Protein Intake and Rehabilitation From Anterior Cruciate Ligament Surgery
Protein supplementation may promote increases in strength and hypertrophy in the context of resistance training (RT) and reduce markers of inflammation, while sufficient levels of protein are necessary for healing certain wounds…
- Trial name
- NCT03614351
- Testing
- Protein (PROT), Control (CONT)
- Sponsor
- Wake Forest University Health Sciences
Renal Injury, Anesthesia
Cardiac and Renal Biomarkers in Arthroplasty Surgery
The investigators will compare the effect of spinal anesthesia to general anesthesia on the level of high sensitivity cardiac biomarkers in patients undergoing hip or knee arthroplasty.
- Conditions
- Renal Injury, Anesthesia, Myocardial Injury, Arthropathy of Knee
- Trial name
- NCT03940651
- Testing
- Spinal Anesthesia, General Anesthetics
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Tibial Fractures
New Bone Fixation Plate for the Repair of Tibial Avulsion Fracture of Posterior Cruciate Ligament of the Knee
To construct a self-designed plate fixation device for posterior cruciate ligament reconstruction, aim to verify its advantages on anatomical knee stability, so as to achieve fracture healing and keep tension after posterior…
- Trial name
- NCT03059368
- Testing
- new bone fixation plate with screw
- Volunteers
- 20 people
- Sponsor
- Cangzhou Central Hospital
ACL, Anterior Cruciate Ligament Injury
Decreasing Knee Injury Risk Factors With Neuromuscular Training
Anterior cruciate ligament (ACL) tears are disabling injuries that place a significant burden on the athlete. Roughly 80% of these injuries are linked to a noncontact mechanism, with more than 70% of them occurring while landing…
- Trial name
- NCT01433718
- Testing
- Neuromuscular and Resistance Training
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ohio University
Anterior Cruciate Ligament Rupture
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
The purpose of this study is to evaluate the accuracy of tunnel positions in anterior cruciate ligament reconstruction
- Trial name
- NCT01267435
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Anterior Cruciate Ligament Rupture
A Clinical Trial of the Round-tunnel and Flat-tunnel Technique of ACL Reconstruction
This study intends to perform round-tunnel and flat-tunnel ACL reconstruction technique in 144 patients, and compare the clinical outcomes of the two surgical procedures through follow-up.
- Trial name
- NCT04953676
- Testing
- round tunnel technique, flat tunnel technique
- Volunteers
- 144 people
- Sponsor
- Peking University Third Hospital
Arthrogenic Muscle Inhibition, Knee Injuries
Effect of Surface EMG Biofeedback on Quadriceps Inhibition Release During Postoperative Knee Rehabilitation
Arthrogenic muscle inhibition (AMI) is a common neurological impairment following knee surgery that limits voluntary quadriceps activation and delays functional recovery.
- Conditions
- Arthrogenic Muscle Inhibition, Knee Injuries, Postoperative Rehabilitation
- Trial name
- BIOQUAD (NCT07736625)
- Testing
- Visual Surface EMG Biofeedback, Standard Rehabilitation Without Visual Biofeedback
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Hopitaux de Saint-Maurice
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
The Rehabilitation Effect of Exercise Training in Cruciate Ligament Reconstruction Patients.
After anterior cruciate ligament (ACL) injury, the involved quadriceps may demonstrate weakness due to decrease in quadriceps activation.
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL - Anterior Cruciate Ligament Deficiency
- Trial name
- NCT03359382
- Testing
- Resistance or home exercise combined with eccentric exercise
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Biologic Augmentation With Mesenchymal Stem Cells in Patients Undergoing Anterior Cruciate Ligament Reconstruction
This study will evaluate the efficacy of biologic augmentation of ACL reconstruction with bone marrow derived mesenchymal stem cells as measured by magnetic resonance imaging to detect graft healing and integration.
- Trial name
- BMAC (NCT04650568)
- Testing
- Autologous Bone Marrow Derived Mesenchymal Stem Cells
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rush University Medical Center
Rupture of Anterior Cruciate Ligament
Multicenter ACL Revision Study (MARS)
The purpose of this study is to determine the effects of modifiable risk factors on patient-reported quality of life, physical activity levels, and risk of early osteoarthritis following revision anterior cruciate ligament (ACL)…
- Trial name
- MARS (NCT00625885)
- Where
- 49 sites in United States, Canada
- Volunteers
- 1,234 people
- Sponsor
- Vanderbilt University Medical Center
Knee Injuries and Disorders
Recovery of Soccer Players After Anterior Cruciate Ligament Reconstruction.
The purpose of this CRT study is to compare clinical and functional outcomes of three graft types ( Quadriceps tendon with bone versus Hamstring tendon versus Quadriceps tendon without bone) for reconstration of anterior cruciate…
- Trial name
- NCT04742868
- Testing
- ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH QUADRICEPS TENDON WITH BONE GRAFT, ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH HAMSTRING TENDON GRAFT, ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION WITH QUADRICEPS TENDON WITHOUT BONE GRAFT
- Where
- 2 sites in Spain
- Volunteers
- 74 people
- Sponsor
- Universidad de Granada
Anterior Cruciate Ligament Rupture, Surgery
ALL Ultrasound Predicts the Success of ACL Repair?
This case series evaluates whether patients with an anterior cruciate ligament (ACL) repair have better outcome if the anterolateral ligament (ALL) was repaired or not considering the ultrasound (US) pre-surgical recommendation.
- Trial name
- ALL_US (NCT04373408)
- Testing
- ACL repair without anterolateral repair, ACL repair with anterolateral repair
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Adrien Schwitzguebel