Clinical trials: Wounds
Wounds
Efficacy Study of GLYC-101 to Evaluate Outcomes After Post-laser Ablation
Study is intended to evaluate safety and efficacy parameters in patients treated with GLYC-101 gel or placebo after laser ablation.
- Trial name
- NCT00656474
- Testing
- GLYC-101 gel (1.0 %)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TR Therapeutics
Ankle Sprain
Open Label Comparative Study On Celecoxib Efficacy And Safety Vs Non-Selective NSAID In Acute Pain Due To Ankle Sprain
To assess the efficacy of celecoxib loading dose of 400mg followed by 200 mg twice a day (BID) versus oral non-selective NSAIDs in acute pain due to ankle sprain.
- Trial name
- NCT00446797
- Testing
- Non-selective NSAIDS, Celecoxib
- Where
- 16 sites in Brazil, Costa Rica and 6 more
- Volunteers
- 278 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Traumatic Brain Injury
Advanced MRI Applications for Mild Traumatic Brain Injury - UCSF
This hypothesis-generating feasibility study compares mTBI Patients and Controls using advanced MRI Applications.
- Trial name
- TBI-2 (NCT02141360)
- Testing
- MRI Diagnostic
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- GE Healthcare
Hip Fractures
Computer-Assisted Fixation of Trochanteric Femur Fractures
The purpose of this study is to assess whether the Stryker© ADAPT™ augmented-reality platform can assist surgeons in optimizing placement of the lag screw component of the Stryker© Gamma™ cephalomedullary nail.
- Trial name
- NCT04528459
- Testing
- Stryker© ADAPT™ platform, Traditional fluoroscopy
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Wounds
Octylseal Surgical Adhesive in General Surgery
The purpose of this study is to evaluate how surgical adhesive is used.
- Trial name
- NCT01514383
- Testing
- Cyanoacrylate (Octylseal )
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Medline Industries
Soft Tissue Injury
A Clinical Trial to Compare Safety and Effectiveness for Relieving Tenderness of 10% Naproxen Gel vs. a 2.32% Diclofenac Diethylamine Gel in the Treatment of Strains and Bruises of the Legs.
Researchers are looking for a different way to treat people who have an injury to their muscles, ligaments, or tendons in their legs or feet. This is known as a "soft tissue" injury.
- Trial name
- NCT05026320
- Testing
- Naproxen gel, Diclofenac gel
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- Bayer
Lower Limb Amputation Above Knee (Injury)
C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
The aim of this post-market study is to confirm that the microprocessor controlled prosthetic knee components (C-Leg 3 and C-Leg 4) in comparison to mechanical knee joints can bring additional benefit to the users primarily on…
- Trial name
- NCT02765035
- Testing
- C-Leg 4, C-Leg 3
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 18 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Chronic Wounds
Evaluation of the Effectiveness of Daily Pulse Lavage Therapy in Chronic Wounds
This study evaluates the effectiveness of pulse lavage therapy in decreasing bacterial counts in chronic wounds.
- Trial name
- PLI2 (NCT01500746)
- Testing
- Pulse lavage treatment, Dressing changes
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Northwestern University
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Tetraplegia
Providing Brain Control of Extracorporeal Devices to Patients With Quadriplegia
This research study is being done to develop a brain controlled medical device, called a brain-machine interface or BMI, that will provide people with a spinal cord injury some ability to control an external device such as a…
- Trial name
- NCT01849822
- Testing
- Neural Prosthetic System
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Richard A. Andersen, PhD
Traumatic Brain Injury, Subarachnoid Hemorrhage
Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention
To show that the use of intravenous levetiracetam(LEV;Keppra)for seizure prevention in patients in the Neuroscience Intensive Care Unit will result in fewer side effects compared to the current standard of care anticonvulsant and…
- Trial name
- Keppra (NCT00618436)
- Testing
- Levetiracetam, Phenytoin
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Cincinnati
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Diabetic Foot Ulcers, Diabetic Foot Wounds
Using Santyl on Diabetic Foot Ulcers
Subjects enrolled in this study will either use Santyl daily or follow standard care procedures for up to 6 weeks for their diabetic foot wound.
- Trial name
- NCT01408277
- Testing
- Santyl, Control
- Where
- 7 sites in United States
- Volunteers
- 55 people
- Sponsor
- Healthpoint
Disorder of Consciousness, Traumatic Brain Injury
Validity and Feasibility of the CRSR-FAST
The CRS-R is a standardized and validated bedside assessment of conscious awareness. It is used routinely for diagnosis and prognosis of patients with disorders of consciousness (DOC) as well as in research settings.
- Trial name
- CRSR-FAST (NCT03549572)
- Testing
- Coma Recovery Scale-Revised
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Massachusetts General Hospital
Facial Injuries, Adipose Tissue
Structural Fat Grafting for Craniofacial Trauma: Repeat Fat Grafting Injection-5 Subject Cohort
Fat grafting represents a technique with great potential to improve outcomes in minimally invasive facial reconstruction. Fat grafting has already been demonstrated as a safe and minimally invasive technique over decades of…
- Trial name
- BTIPlusUp (NCT01822301)
- Testing
- Repeat Fat grafting
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Donor Site Wound
Evaluation of HQ® Matrix Medical Wound Dressing for Healing of Donor Site Wounds
The purpose of the study is to evaluate the safety and effectiveness of HQ® Matrix Medical Wound Dressing for repair of donor site wounds.
- Trial name
- NCT01993030
- Testing
- HQ® Matrix Medical Wound Dressing, Sidaiyi® wound dressing
- Where
- 2 sites in China
- Volunteers
- 71 people
- Sponsor
- Zhejiang Xingyue Biotechnology Co., Ltd.
Distal Radius Fracture
Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures
There is no consensus regarding the need to immobilize the elbow in immediate immobilization of closed distal radius fractures post-reduction.
- Trial name
- NCT02679066
- Testing
- Sugar-tong splint, Short forearm cast
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Surgical Wound
VASCADE ANTEGRADE-PVD Post-Market Registry
The objective of the registry is to collect procedural outcomes data when the Cardiva VASCADE Vascular Closure System (VCS) is used to seal femoral arterial access sites at the completion of ipsilateral peripheral interventional…
- Trial name
- NCT02948257
- Testing
- Cardiva Medical VASCADE VCS
- Where
- 5 sites in United States
- Volunteers
- 52 people
- Sponsor
- Cardiva Medical, Inc.
Brain Tumors, Metastatic Disease
Donepezil in Treating Patients Who Have Undergone Radiation Therapy for Brain Tumors
RATIONALE: Donepezil may help lessen confusion and fatigue and improve mood and quality of life in patients who have undergone radiation therapy for brain tumors.
- Trial name
- NCT00369785
- Testing
- donepezil hydrochloride
- Where
- 16 sites in United States
- Volunteers
- 198 people
- Sponsor
- Wake Forest University Health Sciences
Spinal Cord Injuries
Effect of Vibration Therapy on Bone in Persons With Sub-acute Spinal Cord Injury
The purpose of this research study is to determine the effect of mechanical vibrations on bones of persons with spinal cord injury.
- Trial name
- NCT00886145
- Testing
- Vibration: Right Leg and No Vibration: Left Leg.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- William A. Bauman, M.D.
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