Clinical trials: Wounds
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Cervical Transcutaneous SCS for TBI
The goal of this study is to test the effects of non-invasive electrical stimulation of the spinal cord (called transcutaneous spinal cord stimulation, or tSCS) on arm and hand movement in people with motor impairments after a…
- Trial name
- NCT07147816
- Testing
- Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Roberto de Freitas
Spinal Cord Injury
Developing a Home Telehealth Program to Manage Pressure Ulcers in SCI/D
The Veteran's Health Administration (VHA) is a national leader in using distance technology to monitor patients' self-care via an in-home messaging device with disease management protocols (DMPs).
- Trial name
- NCT00624806
- Testing
- Daily telephone calls, Weekly telephone calls
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Cerebral Palsy
Safety and Effectiveness of Banked Cord Blood or Bone Marrow Stem Cells in Children With Cerebral Palsy (CP).
The purpose of this study is to compare the safety and effectiveness of two types of stem cells,(either banked cord blood or bone marrow), in children between the ages of 2 to 10 years with CP.
- Trial name
- ACT for CP (NCT01988584)
- Testing
- umbilical cord blood (hUCB) cells, bone marrow derived mononuclear cells (BMMNCs)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Meniscus Tear, Tibial, Meniscus Lesion
JuggerStitch Post Market Clinical Follow-up Study
This study is a post-market follow-up study. The data collected from this study will serve the purpose of confirming the safety and performance of the JuggerStitch Device used for meniscal repair according to the product…
- Trial name
- NCT04228367
- Testing
- JuggerStitch Meniscal Repair Device
- Where
- 6 sites in United States, France and 2 more
- Volunteers
- 103 people
- Sponsor
- Zimmer Biomet
Bone Fracture, Radius Fracture
Study on Wood-plastic Composite for Circumferential Casting
The purpose of study is to verify that WOODCAST Circular system performs safely and effectively in its intended use.
- Conditions
- Bone Fracture, Radius Fracture, Ankle Fracture
- Trial name
- WOODCAST (NCT01493167)
- Testing
- limb casting/splinting
- Where
- Finland
- Volunteers
- 97 people
- Sponsor
- Onbone Oy
Post-Traumatic Headache
Treximet for Prevention of Post Traumatic Headache Associated With Cognitive Dysfunction
This study will evaluate the effectiveness of Treximet when taken for post traumatic headache by measuring any change in the number of headache days or any change in a subject's ability to think following treatment with study…
- Trial name
- NCT01053507
- Testing
- sumatriptan/naproxen sodium
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- Cady, Roger, M.D.
Facial Injuries, Tissue Injury
Effect of Concentrating Endogenous Stromal Cells in the Fat Graft Using TGI Device
The overall purpose of this research is to evaluate the physical changes that occur over time after fat grafting for craniofacial trauma.
- Trial name
- AFIRM-TGI (NCT01924364)
- Testing
- Tissue Genesis Cell Isolation System™ (TGI CIS), Standard of care fat grafting
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- J. Peter Rubin, MD
Posttraumatic Stress Disorder, Depression
Trauma Survivors Outcomes and Support Study IV
After traumatic injuries some people have difficulty returning to the routine of their everyday activities and may experience physical and emotional pain.
- Conditions
- Posttraumatic Stress Disorder, Depression, Suicide, Traumatic Brain Injury
- Trial name
- TSOS IV (NCT01625416)
- Testing
- Stepped Care Management
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Washington
Post-Traumatic Stress Disorder
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.
- Trial name
- NCT00739765
- Testing
- Interpersonal Psychotherapy, Prolonged Exposure Therapy, Relaxation Therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- New York State Psychiatric Institute
Brain Injury
Methylphenidate (Ritalin) and Memory/Attention in Traumatic Brain Injury (TBI)
Traumatic brain injury (TBI) is a significant public health problem, with 1.5-2.0 million Americans injured each year. Cognitive deficits, particularly in the domains of memory and attention are frequently the source of lingering…
- Trial name
- NCT00453921
- Testing
- Methylphenidate, Memory and Attention Training
- Where
- 3 sites in United States
- Volunteers
- 76 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Spinal Cord Injuries
Improving Ventilatory Capacity in Those With Chronic High Level SCI
The purpose of this study is to find out if taking the drug Buspar will increase breathing capacity in individuals with spinal cord injuries.
- Trial name
- NCT05041322
- Testing
- Buspirone
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Spaulding Rehabilitation Hospital
Fractures, Bone, Nausea and Vomiting, Postoperative
Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration
The aim of this study is to evaluate not only the occurrence of side effects, but the quality of the recovery (QoR-40 Questionnaire) of patients submitted to spinal anesthesia with administration of low doses (0.1 mg) of…
- Conditions
- Fractures, Bone, Nausea and Vomiting, Postoperative, Pruritus, Morphine Adverse Reaction
- Trial name
- NCT03035942
- Testing
- Dexamethasone, Ondansetron, Saline
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Osteoporosis, Bone Loss
Romosozumab in Women With Chronic SCI
This two-year open-label pilot clinical trial will evaluate the efficacy and safety of romosozumab to treat bone loss in females with chronic spinal cord injury (SCI) and osteoporosis (OP).
- Conditions
- Osteoporosis, Bone Loss, Osteopenia, Osteoporosis, Spinal Cord Injuries
- Trial name
- NCT04708886
- Testing
- Romosozumab, Alendronate
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Northwestern University
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
A potential long-term consequence of anterior cruciate ligament injuries is the development of post-traumatic osteoarthritis in the years following injury.
- Trial name
- NCT04088227
- Testing
- Experimental Group, Control Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Andrews Research & Education Foundation
Nonunion of Fracture of Fifth Metatarsal
A Double-Blind Study on Adjunctive Use of PEMF in the Treatment of 5th Metatarsal Non-Union Fractures
The purpose of this study is to analyze the effect of PEMF in surgical reconstruction of 5th metatarsal non-union fractures.
- Trial name
- NCT00586170
- Testing
- EBI Bone Healing System, Surgery
- Where
- 2 sites in United States
- Volunteers
- 8 people
- Sponsor
- Zimmer Biomet
Chronic Wounds, Diabetic Ulcers
Real-world Study of StimLabs Human Placental Membrane Tissue to Treat Hard-to-Heal Wounds
This is a retrospective, multi-center observational study to assess real-world outcomes of StimLabs human placental membrane tissue used in the treatment of hard-to-heal wounds, including chronic ulcers, diabetic foot ulcers…
- Trial name
- NCT07215741
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- StimLabs
Acute Pain
A Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients
The purpose of this study is to demonstrate the efficacy and safety of Intravenous (IV) acetaminophen plus rescue opioids for the relief of moderate to severe acute pain in neonates and infants (age < 2 years) compared to placebo…
- Trial name
- NCT01635101
- Testing
- IV Acetaminophen, IV Control
- Where
- 22 sites in United States
- Volunteers
- 197 people
- Sponsor
- Mallinckrodt
Anterior Cruciate Ligament Injury
Functional Resistance Training to Improve Knee Function After ACL Reconstruction
The purpose of this study is to examine if thigh muscle weakness and the lack of muscle activation that accompanies ACL injury and reconstruction can be improved with functional resistance training.
- Trial name
- NCT03282565
- Testing
- Functional Resistance Training with Brace, Control, Functional Resistance Training with Elastic Band
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Femoral Fracture
Analysis of the Relationship Between Early Postoperative Anemia and the Evolution of Autonomy at 6 Months in Patients 75 Years of Age and Older Operated on Following a Fracture of the Upper End of the Femur
Fracture of the upper extremity of the femur is a condition whose frequency increases with age. It is a serious disease, with multiple consequences such as a decrease in life expectancy, quality of life and patient autonomy.
- Trial name
- PAAF (NCT03810092)
- Where
- 5 sites in France
- Volunteers
- 255 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Head Injury, Sport Injury
Evidence-based Intervention for Improved Head Impact Safety in Youth Football - Aim 1 and Aim 3
Two middle school (ages 11-14) football teams will be in Aim 1 of this study. All interested athletes on these teams will be invited to voluntarily participate in biomechanical data collection; of those enrolled, 15-20 per team…
- Trial name
- NCT04908930
- Testing
- On-field activity group - Aim 3
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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