Clinical trials: Wounds
Osteoporosis
Secondary Prevention of Osteoporosis
The purpose of this study is to develop and implement an evidence based protocol for the secondary prevention of osteoporotic fractures and falls, and to determine how compliance with this intervention improves muscle strength…
- Trial name
- NCT00421343
- Testing
- alendronate with cholecalciferol, calcium carbonate with cholecalciferol, Falls prevention measures
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Hebrew SeniorLife
Patient Satisfaction, Sports Injury
Virtual Phone Visits Compared to In-Person Physical Visits for Post-Operative Follow-Up at a Sports Medicine Clinic
This study will compare patient reported outcomes (PROs) of patients seen at virtual phone visits compared to in-person visits for 6 weeks, 12 weeks, and 6 months post-operative follow up at a sports medicine clinic.
- Conditions
- Patient Satisfaction, Sports Injury, Surgery, Orthopedic Disorder
- Trial name
- NCT05998148
- Testing
- virtual phone appointment visits
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Jonathan Wu
High Risk Abdominal Wounds
Use of Negative Pressure Wound Therapy in High Risk Surgical Closed Incisions
The purpose of this study is to investigate the use of Negative Pressure Wound Therapy in high risk surgical wounds to evaluate the rate of surgical site infections (SSIs).
- Trial name
- NCT02137447
- Testing
- Negative Pressure treatment
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Subarachnoid Hemorrhage, Intracranial Hemorrhage
Enteral Nutrition and Glycemic Variability Neurological Intensive Care Unit Study
Primary Objective: To determine the effects of a diabetes specific enteral formula compared to a standard formula supplemented with protein (isocaloric and isonitrogenous) on the mean blood glucose and glycemic variability in a…
- Conditions
- Subarachnoid Hemorrhage, Intracranial Hemorrhage, Ischemic Strokes, Subdural Hematoma
- Trial name
- ANUS1014 (NCT01463878)
- Testing
- Glycerna, Jevity - Control Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Eastern Virginia Medical School
Infection, Wound Healing Problem
Fluid Lavage of Open Wounds (FLOW): Pilot Trial
The purpose of this trial is to investigate whether irrigation solution (soap vs. saline solution), or irrigation pressure (high vs. low) will decrease the rate of infection among patients with open fracture wounds.
- Conditions
- Infection, Wound Healing Problem, Nonunion
- Trial name
- FLOW (NCT01069315)
- Testing
- Type of fluid lavage solution, Type of fluid lavage pressure
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 111 people
- Sponsor
- McMaster University
Depression, Traumatic Brain Injury
Mindfulness-Based Cognitive Therapy Intervention to Treat Depression in Individuals With a Traumatic Brain Injury
The purpose of this study is to determine whether mindfulness-based cognitive therapy is effective in reducing depression symptoms in individuals who have experienced a traumatic brain injury.
- Trial name
- NCT00745940
- Testing
- MBCT for TBI
- Where
- 3 sites in Canada
- Volunteers
- 105 people
- Sponsor
- Lakehead University
Pressure Ulcer, Spinal Cord Injuries
Pressure Ulcer Healing With Microcyn
The purpose of this study is to test how well Microcyn™ works on Stage 3 and Stage 4 pressure ulcers compared to sterile saline among persons with spinal cord injury.
- Trial name
- NCT02001558
- Testing
- Microcyn, Sterile saline
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Alabama at Birmingham
Humeral Fractures
Glenohumeral Cortisone Injection
The objective of this project is to determine if giving a cortisone injection to patients with proximal humerus fractures who have stiff shoulders recover their range of motion.
- Trial name
- NCT04216017
- Testing
- kenalog, Lidocaine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Leg Ulcer, Diabetic Foot Ulcer
Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia
The purpose of this reseach study is to determine Mölnlycke Health Care´s Leia dressing performance properties is fulfilled and that the dressing is safe when used on wound types such as pressure ulcer, leg ulcer, and diabetic…
- Conditions
- Leg Ulcer, Diabetic Foot Ulcer, Pressure Ulcer
- Trial name
- NCT01966380
- Testing
- Leia
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Molnlycke Health Care AB
Femoral Neck Fracture
Functional Status, Morbidity and Mortality in Cemented Versus Press-Fit Hemiarthroplasty
Hemiarthroplasty (half of a hip replacement) is the most common treatment for displaced fractures of the femoral neck in the elderly and is associated with a better functional outcome and fewer reoperations than internal…
- Trial name
- NCT01114646
- Testing
- Cemented Hip Hemiarthroplasty, VerSys Beaded FullCoat, Zimmer
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Hartford Hospital
Upper Extremity Injury, Sport Injury
Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Basketball is a challenging sport that requires participants to demonstrate physical fitness and special athletic skills at high levels.
- Conditions
- Upper Extremity Injury, Sport Injury, Shoulder Pain, Muscle Weakness
- Trial name
- NCT04019990
- Testing
- The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Spinal Cord Injury, Sleep Disordered Breathing
Role of Enhancing Serotonin Receptors Activity for Sleep Apnea Treatment in Patients With SCI
The purpose of this study is to look at the effect of exciting using drugs to target a specific pathway in the body, that relies on a natural chemical the body produces called 'serotonin', in patients with spinal cord injury…
- Trial name
- REST-SCI (NCT02458469)
- Testing
- Buspirone, Trazodone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
Cognitive Training for PTSD
Posttraumatic stress disorder (PTSD) is a chronic, disabling condition that occurs in a subgroup of individuals after experiencing traumatic stress, and is common in Veterans seeking mental health treatment at the VA.
- Trial name
- NCT03316196
- Testing
- COGENT COGNITIVE TRAINING, Non training computer condition
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- VA Office of Research and Development
Head Injuries, Facial Injuries
Impact of Helmet Use in Preschool Children
To test the hypothesis if provision of helmet education and free helmet distribution will significantly increase helmet use in preschool children of low-income families compared to those children receiving helmet education…
- Trial name
- NCT01054846
- Testing
- Bicycle helmet from Bell Sports Inc., Bicycle helmet education only
- Where
- United States
- Volunteers
- 609 people
- Sponsor
- Parkview Hospital, Indiana
TBI-Traumatic Brain Injury
Simvastatin for mTBI
Study of simvastatin in Iraq/Afghanistan Veterans with multiple blast exposure and mTBI. The study will measure substances in cerebrospinal fluid (CSF) that are related to dementing disorders.
- Trial name
- NCT01952288
- Testing
- simvastatin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- VA Office of Research and Development
Rotator Cuff Injuries
REGENETEN™ Bioinductive Implant System in Full-thickness Tears
The study is designed to assess the safety and efficacy of Arthroscopic rotator cuff repair (ARCR) augmented with REGENETEN in subjects requiring full-thickness rotator cuff tear repair or revision repair versus Arthroscopic…
- Trial name
- REGENETEN (NCT04450342)
- Testing
- Arthroscopic rotator cuff repair with REGENETEN™ Bioinductive Implant augmentation, Arthroscopic rotator cuff repair, Arthroscopic rotator cuff repair for revision surgery
- Where
- 30 sites in United States, Australia and 6 more
- Volunteers
- 119 people
- Sponsor
- Smith & Nephew, Inc.
Laceration, Abscess
Nitrous Oxide Use in Minor Procedures
Title: High-concentration continuous flow nitrous oxide use for procedural-induced pain or anxiety during pediatric minor procedures.
- Trial name
- NCT01911351
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Type 2 Diabetes Mellitus
Impact of Muscle and Tendon Dysfunction in People With Type 2 Diabetes Mellitus
Diabetes is a chronic-degenerative metabolic disorder that has reached pandemic proportions mainly because of the increasing incidence and prevalence of type 2 diabetes mellitus (T2D).
- Trial name
- T2D_MTU (NCT05585502)
- Testing
- Training (minute oscillation stretching)
- Where
- Italy
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Anterior Cruciate Ligament Rupture
Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction
This study will consist of 80 patients ages 18 to 50 at the Emory Orthopaedic and Spine Center who are undergoing Anterior Cruciate Ligament (ACL) reconstruction with a quadriceps tendon autograft or bone patellar tendon bone…
- Trial name
- NCT02189317
- Testing
- Exparel
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
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