Clinical trials: Wounds and Injuries, Ankles
Pain, Postoperative, Ankle Fracture Surgery
Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very addictive.
- Conditions
- Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence
- Trial name
- BAFA (NCT06949826)
- Testing
- Buprenorphine Transdermal System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jenna-Leigh Wilson
Trimalleolar Fracture, AO Weber C Fractures
Fixation of the Posterior Malleolus in Trimalleolar AO Weber C Fractures.
In AO Weber type C fractures, there is a combination of a proximal fibular fracture, a medial fracture or ruptured deltoid ligament, and a syndesmotic injury.
- Conditions
- Trimalleolar Fracture, AO Weber C Fractures, Syndesmotic Stability, Open Reduction and Internal Fixation
- Trial name
- POSTFIX-C (NCT02599285)
- Testing
- Fixation, NO Fixation
- Where
- 4 sites in Netherlands
- Volunteers
- 54 people
- Sponsor
- Medical Center Haaglanden
Ankle Sprain, Ankle Sprain Strain
The Effects of Vestibulo-Ocular Reflex Exercises Added to Postural Stabilization Training in Amateur Athletes With Chronic Ankle Instability
Chronic ankle instability (CAI) is a common condition after lateral ankle sprain. CAI is characterized by mechanical and/or functional instability, or recurrent episodes of "giving way," persisting for at least 12 months after…
- Conditions
- Ankle Sprain, Ankle Sprain Strain, Ankle Inversion Sprain
- Trial name
- NCT07760233
- Testing
- Postural Stabilization Training, Vestibulo-Ocular Reflex Exercise in addition to Postural Stabilization Training
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Bahçeşehir University
Ankle Fractures
Postoperative Aspirin and Ankle Fracture Healing
This study aims to identify if postoperative aspirin use leads to a delay in fracture healing. NSAIDs have long been avoided in the management of fractures, due to the belief that they may impair fracture healing.
- Trial name
- NCT03765619
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Ankle Injuries, Syndesmotic Injuries
Comparison of Screw and Suture Button Technique Results in Ankle Syndesmosis Injuries
In this study, syndesmosis injuries were detected in 143 of the patients who came to Atatürk University Faculty of Medicine, Orthopedics and Traumatology clinic from October 2017 to October 2021 with ankle fractures.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Tibiofibular; Dislocation Distal
- Trial name
- NCT05538845
- Testing
- Screw fixation, Suture button
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ataturk University
Pain, Postoperative, Ankle Fractures
Perfusion Index and Pain in Ankle Surgery
Perfusion index (PI) measured via a pulse oximeter has been shown to correlate with activation of the sympathetic nervous system, such as by pain stimulation, as a result of involuntary contraction of the arterioles.
- Trial name
- PIPA (NCT03158753)
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Rune Sort
Ankle Sprains
Approach to Ankle Sprains in the Emergency Department
The aim of this study is to evaluate the short-term effects of routinely applied agents on pain and joint range of motion (ROM) in ankle sprains presenting to the emergency department (ED).
- Trial name
- NCT06563271
- Testing
- Dexketoprofen Trometamol 50 Mg/mL Solution for Injection, Ibuprofen 100 MG/ML Solution for Injection, Paracetamol 10 Mg/mL Solution for Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Ankle Sprains
Urdu Version Of Cumberland Ankle Instability Tool: Reliability And Validity Study
The purpose of this study is to check reliability and validity, of translated Urdu version of the Cumberland Ankle Instability Tool develop and test its psychometric properties and responsiveness in Urdu speaking population in…
- Trial name
- NCT05412186
- Where
- Pakistan
- Volunteers
- 125 people
- Sponsor
- Riphah International University
Joint Instability, Chronic Disease
Jumping Exercises Approach in Individuals With Chronic Ankle Instability
The aim of this pilot study is to analyze the effect of a 12-week specific jump training compared with conventional therapy in patients with chronic functional instability of the ankle.
- Conditions
- Joint Instability, Chronic Disease, Sprains
- Trial name
- NCT02115971
- Testing
- Jumping exercise, Strength exercise
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Swanenburg
Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
The Effect of Low-Intensity Blood Flow Restriction Therapy on the Management of Acute Ankle Sprains
The primary objective of this study is to evaluate the feasibility of implementing BFR in the rehabilitation treatment of isolated ankle sprains as well as to evaluate the clinical benefits of BFR when compared to standard…
- Conditions
- Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree, Musculoskeletal Injury
- Trial name
- NCT05596162
- Testing
- Blood Flow Restriction Therapy, Standard Physical Therapy
- Where
- United States
- Sponsor
- Vanderbilt University Medical Center
Ankle Sprains
Fear of Movement, Functionality and Quality of Life in Elite Athletes With an Ankle Instability History
Ankle sprain is frequently experienced by individuals participating in different sports activities. Ankle sprains have been shown to result in a decrease in level of physical activity and persistence of some symptoms for a long…
- Trial name
- NCT04789369
- Testing
- Questionnaires
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Acibadem University
Trauma
Unimalleolar Versus Bimalleolar Fixation in Bi- or Trimalleolar Ankle Fracture
A one third of all ankle fractures are bi- or trimalleolar. Traditionally these fractures are treated by both medial and lateral osteosynthesis, sometimes accompanied by osteosynthesis of the posterior malleolus.
- Trial name
- NCT01757951
- Testing
- Unimalleolar fixation, Bimalleolar fixation
- Where
- Finland
- Volunteers
- 126 people
- Sponsor
- University of Oulu
Ankle Fractures
Intramedullary Nailing Versus Plate Fixation of Ankle Fractures. A Prospective, Randomized Controlled Trial.
The purpose of this study is to make a survey of functional outcome, radiological outcome and complication rate after intramedullary nailing (IMN) and plate fixation of Weber B ankle fractures in elderly patients, and contribute…
- Trial name
- NCT03377205
- Testing
- Compression screws and neutralization plate, Acumed Fibular Rod System
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Ankle Fractures
Combined Randomised and Observational Study of Type B Ankle Fracture Treatment
This study will determine whether operative management confers improved short and long-term outcomes for patients with isolated AO type 44-B1 distal fibula fractures when compared with non-operative management.
- Trial name
- CROSSBAT (NCT01134094)
- Testing
- Open reduction internal fixation of the ankle, Non Operative
- Where
- 21 sites in Australia
- Volunteers
- 160 people
- Sponsor
- The University of New South Wales
Syndesmotic Injuries
Syndesmotic Screw in Neutral Position Versus Maximum Ankle Dorsiflexion in Ankle Fractures; Comparative Study.
Ankle fracture is one of the most common orthopedic injuries. Approximately, 20% of surgically treated ankle fractures are associated with syndesmotic instability.According to the mechanism of the injury the syndesmotic…
- Trial name
- NCT06313177
- Testing
- syndesmosis fixation with screws
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Post-traumatic; Arthrosis, Tibial Fractures
Does Joint Lavage Reduce Intraarticular Inflammation in High-energy Tibial Pilon Fractures?
High-energy tibial pilon fractures have historically been associated with poor outcomes largely due to the elevated risk of severe post-traumatic arthritis.
- Conditions
- Post-traumatic; Arthrosis, Tibial Fractures, Post-Traumatic Osteoarthritis of Ankle
- Trial name
- NCT05652881
- Testing
- Joint Lavage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Incision, Foot Ankle Injuries
Staple Versus Suture Closure for Foot and Ankle Surgery
This study aims to determine if staples or sutures are better for the closure of uncomplicated foot and ankle surgeries. Currently, most surgeons base their choice for closure on previous teaching from a mentor during fellowship…
- Trial name
- NCT03522753
- Testing
- Metal skin staples, Nylon sutures
- Sponsor
- University of Alabama at Birmingham
Shoulder Injuries, Knee Injuries
Clinical Comparative Study of Personalized Shoulder, Knee and Ankle Brace
This study is based on human anatomical data and uses computer-aided engineering (CAE) software such as biomedical image processing software, reverse engineering software, CAD software, and finite element analysis software to…
- Conditions
- Shoulder Injuries, Knee Injuries, Ankle Injuries
- Trial name
- NCT04936412
- Testing
- Rehabilitation brace
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Jia-kuo yu
Sprain of Ankle
Evaluation of the Effect of the Association of Proton Pump Inhibitor (PPIs) With Non-Steriodal Anti-Inflamatories (NSAIDs) in Work Leave Time.
Retrospective cohort study to evaluate the effect of the association of PPIs with NSAIDs in work leave time.
- Trial name
- NCT00717119
- Where
- Spain
- Volunteers
- 6,356 people
- Sponsor
- AstraZeneca
Ankle Sprain
A Comparison of Early Mobilization Versus Traditional Treatment for Acute Ankle Sprains.
Acute ankle sprain is one of the most common musculoskeletal injuries, accounting for an estimated 2 million injuries per year and 20% of all sports injuries in the United States.
- Trial name
- NCT01134653
- Testing
- Jump Stretch
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Nationwide Children's Hospital