Clinical trials: Wounds and Injuries, Ankles
Ankle Injuries
Neurophysiology of Ankle Instability
Chronic ankle instability (CAI) is a common debilitating orthopedic condition that disrupts physical function and decreases quality of life. Not all CAI is the same.
- Trial name
- NCT06576687
- Testing
- Physical Rehabilitation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Ankle Fracture
Exparel and Ankle Surgery
This study involves a drug called Exparel that has been approved by the US Food and Drug Administration (FDA), for application directly to wound sites. EXPAREL® is a long acting pain reliever.
- Trial name
- NCT02072135
- Testing
- Exparel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Ankle Injuries, Syndesmotic Injuries
Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures
Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain
- Trial name
- NCT05190874
- Testing
- Grappler Interference Screw System
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Paragon 28
Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus
Operative Treatment of Ankle Fractures
Patients who underwent operative treatment of an ankle fracture with or without following removal of the osteosynthetic material are examined by a specific ankle provocation test, a questionnaire and X-Rays to evaluate the…
- Conditions
- Ankle Fracture, Trimalleolar, Ankle Fracture - Lateral Malleolus, Ankle Fracture, Bimalleolar
- Trial name
- NCT04437355
- Testing
- Specific provocation test
- Where
- Switzerland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Spital Limmattal Schlieren
Ankle Fractures, Trauma Injury
Effect of Toradol on Post-operative Foot and Ankle Healing
The use of Toradol for pain control in surgical orthopedic cases is currently a topic of interest within the field. The proposed study is a prospective randomized study evaluating postoperative pain, opioid requirement…
- Trial name
- NCT03727048
- Testing
- Ketorolac, No ketorolac
- Volunteers
- 128 people
- Sponsor
- Rothman Institute Orthopaedics
Ankle Fracture, Ankle Arthrodesis
Compression Therapy for Swelling Management Following Ankle Injury
After an injury or undergoing foot/ankle surgery, patients often experience swelling in the injured area. Under current standard of care, plaster casts are removed at six weeks and patients are put in a walking boot.
- Trial name
- NCT06772649
- Testing
- Compression sleeve
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Ankle Injuries, Fracture, Ankle
Patient Education Using 3D Printed Model
Complex high energy fractures of the lower extremity are life changing injuries and are known to be associated with poor functional outcome post operatively.
- Trial name
- NCT04009252
- Testing
- 3D Model Education
- Volunteers
- 28 people
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Injuries, Knee Injuries
Clinical Comparative Study of Personalized Shoulder, Knee and Ankle Brace
This study is based on human anatomical data and uses computer-aided engineering (CAE) software such as biomedical image processing software, reverse engineering software, CAD software, and finite element analysis software to…
- Conditions
- Shoulder Injuries, Knee Injuries, Ankle Injuries
- Trial name
- NCT04936412
- Testing
- Rehabilitation brace
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Jia-kuo yu
Chronic Ankle Instability, Ankle Sprains
A Study Investigating The Effects Of An Ankle Rehabilitation Program On High School Athletes With Ankle Instability
A randomized controlled trial investigating the effects of a 4-week ankle rehabilitation program on high school athletes with chronic ankle instability.
- Conditions
- Chronic Ankle Instability, Ankle Sprains, Ankle Rehabilitation
- Trial name
- NCT03447652
- Testing
- Resistance Band Ankle Rehabilitation, Biomechanical Ankle Platform System Rehabilitation, Combination Rehabilitation
- Where
- 7 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Ankle Injuries and Disorders
Balance Training With tDCS for CAI
The purpose of this research study is to examine the efficacy of non-invasive brain stimulation in addition to balance exercise for chronic ankle instability (CAI), a condition that develops following an initial ankle sprain…
- Trial name
- NCT04390048
- Testing
- Anodal tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Miami
Balance; Distorted
Plyometrics in the Ankle Stabilizing Muscles in Improving Balance in Ballerinas
Balance is essential for successful dance performance. The effort of salsa dancers is given by the levels of stability, produced by the muscular activation of lower limbs.
- Trial name
- NCT04306068
- Testing
- Plyometric protocol
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Pain, Ankle Injuries
Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
This study evaluates the location, frequency and duration of secondary site pain relating to immobilization in a CAM walker boot.
- Trial name
- NCT03312933
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Brigham and Women's Hospital
Osteochondral Lesion of Talus, Chondral Defect
AMIC vs. MFx in the Ankle
This clinical investigation is a prospective, double blind, single-centre, randomised controlled trial comparing arthroscopic autologous matrix induced chondrogenesis (AMIC®) to microfracture alone in the treatment of…
- Conditions
- Osteochondral Lesion of Talus, Chondral Defect, Microfracture
- Trial name
- AMARTA (NCT05741983)
- Testing
- Microfracture (MFx), Chondro-Gide®
- Where
- United Kingdom
- Sponsor
- Geistlich Pharma AG
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Ankle Fractures
Immediate Vs. Delayed Weight Bearing Postoperative Protocol in Diabetic Ankle Fractures
Operatively managed diabetic ankle fractures have significant risk for complications. The cause for failure is likely multifactorial, however, a component of failure has to do with an inability to process pain and pressure…
- Trial name
- Diabetic Ankle (NCT03966027)
- Testing
- Postoperative protocol (Immediate weight bearing), Postoperative Protocol (Delayed Weight Bearing)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Kyle Schweser MD
Running, Leg Injuries
Exercise Interventions, Running Biomechanics and Injury in Novice Runners
The purpose of this study is to understand the effects of muscle strengthening and balance exercise interventions on muscle strength, running mechanics and postural control in novice recreational runners.
- Trial name
- NCT01900262
- Testing
- Strengthening, Balance Training, Stretching
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Ankle Sprain
Changes in Brain-Muscle Coupling After Microneedle-Knife Therapy for Ankle Sprain
This study evaluated changes in brain-muscle coordination in patients with ankle sprain after one session of microneedle-knife therapy.
- Trial name
- NCT07839260
- Testing
- Microneedle-Knife Therapy
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Affiliated Dongyang Hospital of Wenzhou Medical University
Ankle Injuries and Disorders, Foot Injuries and Disorders
The Aim of Study is Translate and Adapt the Visual Analog Scale Foot and Ankle (VAS-FA) Instrument Into Turkish and Psycho-metrically Test Its Reliability and Validity Among Patients Who Had Foot and Ankle Disorders or Surgery
There have previously been no validated a specific foot and ankle patient-reported outcome measures in Turkish. The Visual Analogue Scale Foot and Ankle (VAS-FA) will translated and adapted into Turkish language.
- Trial name
- NCT03262324
- Testing
- VAS-FA Turkish version
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Hasan Kalyoncu University
Ankle Fractures
Randomized Controlled Trial for Ankle Fracture Pain Control
This project is a multicenter, three armed, prospective randomized control trial studying the effectiveness of a long-acting local anesthetic "cocktail" in patients undergoing operative fixation of ankle fractures.
- Trial name
- NCT03696199
- Testing
- Long-Acting Local Anesthesia, Regional Anesthesia
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Lahey Clinic
Ankle Fractures
Prognostic Factors Following Ankle Fractures
Ankel fractures is a common fracture. Most patients experience that the regain normal range of motions and limited pain within the first 6 months following ankel fracture, but not all.
- Trial name
- NCT03741556
- Testing
- questionaire
- Where
- 3 sites in Denmark
- Volunteers
- 160 people
- Sponsor
- Sygehus Lillebaelt