Clinical trials: Wrinkle
Nasolabial Folds
Radiesse® Injectable Dermal Filler for the Treatment of Nasolabial Folds in Persons of Color
Post marketing study to assess the likelihood of hypertropic scarring, keloid formation and hyper- or hypopigmentation in patients with Fitzpatrick Skin Types IV, V, and VI receiving nasolabial fold treatment with Radiesse®…
- Trial name
- NCT01012388
- Testing
- Radiesse® Injectable Dermal Filler
- Where
- 5 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merz North America, Inc.
Jowls
Jowl Improvement With Injectable Fillers
This is a prospective clinical study to demonstrate a reduction in jowling and laxity of the jawline that can be achieved following facial volume enhancement using JUVÉDERM VOLUMA™ XC (0.3% w/w lidocaine).
- Trial name
- NCT04389866
- Testing
- JUVÉDERM VOLUMA™ XC
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Advanced Dermatology
Wrinkles
Efficacy and Tolerability of SkinPen on Male and Female Subjects' Wrinkles of the Neck
This single-center, the clinical trial is being conducted over the course of 90 days followed by 1-month and 6-month post-treatment visits in order to assess the efficacy and tolerability of the Sponsor's SkinPen device when used…
- Trial name
- NCT03803059
- Testing
- SkinPen Precision
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Nasolabial Folds, Marionette Lines
Emervel for the Correction of Lower Face Wrinkles & Folds
This study is designed to 1. evaluate the naturalness of facial expressions in motion (2D video images), by treating investigator assessment 2.
- Conditions
- Nasolabial Folds, Marionette Lines, Wrinkles
- Trial name
- NCT02718040
- Testing
- Emervel Classic and/or Deep Treatment Group
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkle, Benign Pigmented Lesions
Post Market Study To Collect Efficacy Data For The Treatment Of Wrinkles With A Radiofrequency Device
The intended use of the RF (radiofrequency) device used in this study is to assess the efficacy of the handpiece for the treatment of facial wrinkles.
- Conditions
- Wrinkle, Benign Pigmented Lesions, Benign Vascular Lesions
- Trial name
- NCT05096247
- Testing
- TempSure, Icon
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Cynosure, Inc.
Aging, Pain
Safety and Efficacy of the Addition of 0.3% Lidocaine With EVOLENCE®
The study doctor will give EVOLENCE® mixed with Lidocaine to people in this study to see if it effectively reduces pain while injecting and works to correct nasolabial wrinkles.
- Trial name
- AD-1016 (NCT00929071)
- Testing
- Evolence, Lidocaine, topical anesthetic
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weinkle, Susan H., M.D.
Wrinkles
Safety Study of Cosmetic Tissue Augmentation in People of Color
Elevess is intended for all skin types. However, further study of all soft tissue fillers is needed in people of color because of the increasing use of cosmetic dermal filler products.
- Trial name
- NCT01147172
- Testing
- Elevess
- Where
- 9 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anika Therapeutics, Inc.
Wrinkle, Nasolabial Fold
RHA® 4 NLF Cannula
This is a randomized, controlled, single-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA®4 injected in NLFs with a cannula is non-inferior to RHA®4 injected in NLFs with a sharp…
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Trial name
- NCT04754646
- Testing
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Peri-oral Wrinkles
Study of Restylane and Perlane in the Correction of Peri-Oral Wrinkles
This is an open-label study to assess safety using Restylane and Perlane in the correction of facial wrinkles.
- Trial name
- NCT00977704
- Testing
- Restylane and Perlane
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Medicis Global Service Corporation
Wrinkles in Decolletage
An Open-label Study of Poly-l-lactic Acid for Correction of Wrinkles in the décolletage Area
This is a prospective open-label study to evaluate safety and effectiveness of two different reconstitution volumes of poly-l-lactic acid (PLLA) for correction of wrinkles in the décolletage area.
- Trial name
- NCT05538728
- Testing
- poly-l-lactic acid (Sculptra)
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Skin Wrinkling
Emervel® Deep Lidocaine vs. Juvederm® Ultra Plus in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of the study was to compare the effectiveness and safety of Emervel Deep Lidocaine versus Juvederm Ultra Plus in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205061
- Testing
- Emervel Deep Lidocaine, Juvederm Ultra Plus
- Where
- 11 sites in United States
- Volunteers
- 162 people
- Sponsor
- Galderma R&D
Bilateral Nasolabial Fold Wrinkles
Safety and Efficacy Study of Isolagen Therapy in the Treatment of Nasolabial Fold Wrinkles
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM compared with placebo when administered to bilateral nasolabial fold wrinkles.
- Trial name
- NCT00655356
- Testing
- Autologous Human Fibroblasts (azficel-T)
- Where
- 6 sites in United States
- Volunteers
- 218 people
- Sponsor
- Castle Creek Biosciences, LLC.
Wrinkles
Safety and Efficacy of a Metallic Cannula Versus A Standard Needle for Soft Tissue Augmentation of the Nasolabial Folds
The purpose of this study was to assess the safety and efficacy of a new metallic cannula to inject hyaluronic acid for dermal augmentation in the nasolabial folds compared to standard needle.
- Trial name
- NCT01066026
- Testing
- hyaluronic acid with metallic cannula or standard needle., Hyaluronic acid injected with the new tool.
- Where
- 2 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic