Clinical trials: Wrinkles
Wrinkle, Benign Pigmented Lesions
Post Market Study To Collect Efficacy Data For The Treatment Of Wrinkles With A Radiofrequency Device
The intended use of the RF (radiofrequency) device used in this study is to assess the efficacy of the handpiece for the treatment of facial wrinkles.
- Conditions
- Wrinkle, Benign Pigmented Lesions, Benign Vascular Lesions
- Trial name
- NCT05096247
- Testing
- TempSure, Icon
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- Cynosure, Inc.
Perioral Rhytids, Aging
RHA Redensity - Perioral Rhytids
Randomized, blinded, No-Treatment control, multi-center, prospective clinical study, to identify whether TEOSYAL RHA® Redensity is more effective than No-Treatment in the correction of moderate to severe dynamic perioral rhytids…
- Conditions
- Perioral Rhytids, Aging, Wrinkle
- Trial name
- NCT03092219
- Testing
- TEOSYAL RHA Redensity
- Where
- 8 sites in United States, Canada
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Wrinkle, Rhytides
Renuvion Dermal System for Dermal Resurfacing
This is a multi-center, single arm, evaluator-blind prospective study of up to 55 study subjects who are seeking a procedure to reduce the appearance of wrinkles and rhytides.
- Trial name
- NCT04185909
- Testing
- Renuvion Dermal System
- Where
- 4 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Lateral Canthal Lines
Efficacy and Safety of Increasing Doses of DaxibotulinumtoxinA for Injection (DAXI for Injection) in the Treatment of Moderate or Severe Lateral Canthal Lines
A Phase 2a, Multicenter, Open-Label, Dose-Escalation Study to Evaluate the Treatment of Moderate or Severe Lateral Canthal Lines (LCL).
- Trial name
- NCT03911102
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 4 sites in United States
- Volunteers
- 63 people
- Sponsor
- Revance Therapeutics, Inc.
Wrinkle
To Show the Safety and Effectiveness of the Demetech Barbed Polydioxanone (PDO) Suture
The clinical trial, sponsored by Sutura Medical Technology, Inc., is a pivotal, blinded, multi-center study assessing the safety and effectiveness of the Demetech Barbed PDO Suture, an absorbable Polydioxanone suture, for the…
- Trial name
- NCT06404372
- Testing
- Demetech Barbed PDO Suture
- Where
- 4 sites in United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Sutura Medical Technology LLC
Facial Rhytides, Glabellar Rhytides
A Safety and Efficacy Study of OnabotulinumtoxinA in Upper Facial Rhytides
This is a safety and efficacy study of onabotulinumtoxinA in subjects with upper facial rhytides (forehead lines, glabellar lines, lateral canthal lines [crow's feet lines]).
- Trial name
- NCT02261493
- Testing
- OnabotulinumtoxinA, Normal Saline
- Where
- 24 sites in United States, Belgium and 2 more
- Volunteers
- 787 people
- Sponsor
- Allergan
Rosacea, Wrinkles
Safety and Efficacy of the Luxe Device to Treat Facial Wrinkles and Rosacea
This study is designed to evaluate the efficacy and safety of the Luxe™ device for use in wrinkle and rosacea treatment. Up to 60 subjects will treat their periorbital and cheek areas daily for 4 weeks and then twice a week for…
- Trial name
- NCT01618864
- Testing
- Luxe
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Facial Wrinkles
Evaluation of the Safety and Efficacy of CosmetaLife™ for the Correction of Nasolabial Folds
This is a randomized, double-blind pivotal study to evaluate the safety and effectiveness of CosmetaLife injectable dermal filler for the correction of wrinkles and folds, such as nasolabial folds (i.e., smile lines).
- Trial name
- NCT00414544
- Testing
- CosmetaLife, Restylane
- Where
- 5 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Cosmeta
Wrinkle Reduction
Pivotal Study of the Cutera truSculpt Radiofrequency Device for Wrinkle Reduction
The purpose of this pivotal investigation is to evaluate the safety and efficacy of the Cutera truSculpt™ radiofrequency (RF) Device for Wrinkle Reduction.
- Trial name
- NCT03285581
- Testing
- truSculpt RF
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Wrinkles
Safety Study of Cosmetic Tissue Augmentation in People of Color
Elevess is intended for all skin types. However, further study of all soft tissue fillers is needed in people of color because of the increasing use of cosmetic dermal filler products.
- Trial name
- NCT01147172
- Testing
- Elevess
- Where
- 9 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anika Therapeutics, Inc.
Cheek, Wrinkle
Open Label Extension for 43USSA1812
To evaluate long-term safety and effectiveness data of Sculptra Aesthetic beyond the Month 12 duration of the pivotal study 43USSA1812 (NCT04124692) to help characterize the long-term safety and effectiveness profile of the more…
- Trial name
- NCT04595331
- Testing
- Sculptra Aethestic reconsituted with 8ml Sterile Water for Injection
- Where
- 13 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkles, Rhytides
TriActive+ Radiofrequency (RF) for Non-Invasive Treatment of Wrinkles and Rhytides
The study objective is to evaluate the safety and efficacy of a radiofrequency (RF) source, the TriActive+ RF handpiece, for treatment of wrinkles and rhytides after multiple treatments.
- Trial name
- NCT01859611
- Testing
- TriActive+ RF
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- El. En. SpA
Tightening of Skin Laxity
Application of the Apsara Thermal Wand System
The purpose of this feasibility study is to gain an initial assessment of the acute safety and performance of the Apsara Thermal Wand System in human facial tissue.
- Trial name
- NCT00662389
- Testing
- Apsara Thermal Wand System
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Apsara Medical Corporation
Skin Aging
Evaluation of the Efficacy and Tolerance of a Light Therapy Mask on Mild to Moderate Brown Spots and Moderate to Severe Facial Wrinkles
This research study will test how well a light therapy mask works for women with mild to moderate hyperpigmentation (brown spots) and moderate to severe facial wrinkles, as compared to a "sham" or inactive investigational light…
- Trial name
- NCT03312543
- Testing
- Active Mask
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Wrinkle, Photoaging
Comparison of the Cosmetic Effects of Bakuchiol and Retinol
Subjects will be assigned to a retinoid cream or bakuchiol to compare the cosmetic effects. This will take place over a 12 week period.
- Trial name
- NCT03112863
- Testing
- Bakuchiol, Retinol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Facial Wrinkles
Safety and Effectiveness of Belotero® in Subjects With Fitzpatrick Phototypes IV Through VI
This is a study to assess how safe and effective an investigational product, Belotero® is in people with all skin types with facial wrinkles, such as nasolabial folds.
- Trial name
- NCT00922623
- Testing
- Belotero®
- Where
- 3 sites in United States
- Volunteers
- 93 people
- Sponsor
- Merz North America, Inc.
Cosmetic Techniques
Evaluation of Four Injectable Neuromodulators in the Glabella Area Glabella Area
The purpose of the study is to use 3D imaging to evaluate the effects of four FDA approved neuromodulators on facial lines, wrinkles and animation.
- Trial name
- JBDX (NCT05167864)
- Testing
- Onabotulinumtoxina for Injection, Abobotulinumtoxina for Injection, IncobotulinumtoxinA for Injection
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Pennsylvania
Skin Wrinkling
Emervel® Deep Lidocaine vs. Juvederm® Ultra Plus in Treatment of Moderate to Severe Facial Wrinkles and Folds
The purpose of the study was to compare the effectiveness and safety of Emervel Deep Lidocaine versus Juvederm Ultra Plus in the treatment of moderate to severe facial wrinkles and folds.
- Trial name
- NCT01205061
- Testing
- Emervel Deep Lidocaine, Juvederm Ultra Plus
- Where
- 11 sites in United States
- Volunteers
- 162 people
- Sponsor
- Galderma R&D
Facial Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines and Frown Lines
This study will evaluate the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of Crow's Feet Lines and Frown Lines (Facial Rhytides)
- Conditions
- Facial Rhytides, Crow's Feet Lines, Glabellar Lines
- Trial name
- NCT01189760
- Testing
- onabotulinumtoxinA 24 U, onabotulinumtoxinA 44 U, normal saline
- Where
- 4 sites in United States, Canada and 2 more
- Volunteers
- 917 people
- Sponsor
- Allergan
Disorder of Soft Tissue
Safety Evaluation of Aline HA, an Implanted Cross-Linked HA Device
The protocol hypothesis is that treatment with Aline HA™ will be safe through 6 months as determined by clinical assessment of treatment sites and routine tracking of adverse events.
- Trial name
- NCT01708213
- Testing
- Aline HA
- Where
- 2 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- TauTona Group