Clinical trials: Written Exposure Therapy, active
Stress Disorders, Post-Traumatic, Substance-Related Disorders
RISE for PTSD and Substance Use Disorder in Veterans
Veterans with co-occurring posttraumatic stress disorder (PTSD) and substance use disorder (SUD) experience significant impairment and worse treatment outcomes compared to those with either condition alone, including higher rates…
- Trial name
- RISE (NCT07903753)
- Testing
- Written Exposure Therapy, Cognitive Behavioral Therapy for Substance Use Disorders (skill components), Cognitive Behavioral Therapy for Substance Use Disorders
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
PTSD - Post Traumatic Stress Disorder, Substance Use Disorder (SUD)
Mechanisms of Written Exposure Therapy in Residential SUD Treatment
The goal of this clinical trial is to learn how Written Exposure Therapy (WET), a brief treatment for PTSD, works among individuals with substance use disorders (SUD) engaged in residential SUD treatment and how biology may…
- Trial name
- NCT07397507
- Testing
- Written Exposure Therapy, Neutral Writing
- Volunteers
- 108 people
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder (PTSD)
EEG and Actigraphy Biomarkers of Written Exposure Therapy for Posttraumatic Stress Disorder
Posttraumatic stress disorder, or PTSD, can affect emotional health, sleep, daily functioning, and quality of life. Written Exposure Therapy is a brief trauma-focused psychotherapy in which participants complete structured…
- Trial name
- TREAT (NCT07766798)
- Testing
- Written Exposure Therapy, Neutral Writing Condition
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mclean Hospital
Posttraumatic Stress Disorder (PTSD), Substance Use Disorder (SUD)
Written Exposure in Substance Treatment (WEST 3.0): Randomized Controlled Trial
The purpose of the current research study is to evaluate the efficacy of the refined Written Exposure in Substance Treatment (WEST) for PTSD among residential SUD patients through a randomized controlled trial.
- Trial name
- WEST (NCT07782268)
- Testing
- Written Exposure Therapy, Treatment as Usual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Potomac Health Foundations
Suicide, Attempted, Suicide Threat
Written Exposure Therapy for Suicide Prevention
Military service members admitted to inpatient psychiatry for self-injurious thoughts and behaviors (SITBs) represent an at-risk group for continued SITBs and rehospitalizations in the post-discharge period.
- Trial name
- NCT05878795
- Testing
- WET-SP, TAU
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Boston University
PTSD - Post Traumatic Stress Disorder
Advancing Skills Through Consultation, Education, and Novel Technologies
This research study tests strategies to train behavioral health providers in Written Exposure Therapy (WET), an evidence-based treatment for posttraumatic stress disorder (PTSD).
- Trial name
- ASCENT (NCT07707102)
- Testing
- Live workshop, AI-enhanced Web-based training, Consultation video calls
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Eating Disorders
Be Body Brave: Digital Written Exposure Therapy for Eating Disorders
Current eating disorder (ED) treatment options are both inaccessible (80% of people with EDs do not access treatment) and not entirely successful (most people with an ED do not reach full remission).
- Trial name
- BBB (NCT07914712)
- Testing
- Imaginal exposure, Eating disorder journaling
- Volunteers
- 900 people
- Sponsor
- University of Louisville
Post Traumatic Stress Disorder
Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI
In this study, the investigators are evaluating whether transcranial direct current stimulation (tDCS), a brain stimulation technique, can be combined with Written Exposure Therapy (WET), a standard talk therapy for posttraumatic…
- Trial name
- NCT07715799
- Testing
- Transcranial Direct Current Stimulator, Written Exposure Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Post Traumatic Stress Disorder
rTMS-augmented Written Exposure Therapy for PTSD
Post-traumatic stress disorder (PTSD) is prevalent and represents a high healthcare burden among Veterans. Repetitive transcranial magnetic stimulation (rTMS) is a brain-based therapy that may be effective for treating PTSD.
- Trial name
- NCT05149534
- Testing
- Written Exposure Therapy, repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- VA Office of Research and Development
Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms
Developing and Testing Innovative Care Pathways for Screening and Treatment of OUD/PTSD in Jails
Opioid overdose is the leading cause of death among people recently released from incarceration. Recent evidence also shows a rise in stimulant use among justice-involved populations, as well as growing rates of concurrent opioid…
- Conditions
- Post-traumatic Stress Disorder (PTSD), Post-traumatic Stress Symptoms, Opioid Use Disorder (OUD), Stimulant Use Disorder
- Trial name
- HOPE (NCT07490717)
- Testing
- Cognitive Processing Therapy (CPT), Written Exposure Therapy (WET)
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- University of Arkansas
PTSD - Post Traumatic Stress Disorder
Written Exposure Therapy Plus Adjunctive Methylphenidate Treatment for Veterans With PTSD
Many Veterans with post-traumatic stress disorder (PTSD) do not fully benefit from the best current treatments, some of which focus on helping the brain regulate trauma memories.
- Trial name
- WET+MPH (NCT07904000)
- Testing
- Written Exposure Therapy (WET), methylphenidate (MPH)
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- VA Office of Research and Development
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Group Guided Written Exposure Therapy for CPTSD Symptoms Among Adolescents
This study aims to examine the effectiveness of group-delivered Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT06931093
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive counselling
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Written Exposure Therapy, Breathing Techniques
Early Intervention for Postpartum PTSD: Comparing Written Exposure and Capnometry-Guided Breathing Therapy
The purpose of this study is to examine two early interventions, Written Exposure Therapy and Capnometry Guided Breathing, to reduce post-traumatic stress disorder (PTSD) symptoms in women after childbirth as compared to usual…
- Conditions
- Written Exposure Therapy, Breathing Techniques, PTSD (Childbirth-Related), Postpartum Care
- Trial name
- NCT07342530
- Testing
- Written Exposure Therapy (WET), Capnometry-Guided Breathing Intervention (CGRI)
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Post Traumatic Stress Disorder, Written Exposure Therapy
Behavioral Health Technician Delivered Written Exposure Therapy
This study has two main goals. First, it aims to test a treatment called written exposure therapy to see if it can help military service members who have posttraumatic stress disorder (PTSD).
- Trial name
- NCT06789887
- Testing
- Written Exposure Therapy, Treatment as Usual (TAU)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Palo Alto Veterans Institute for Research
PTSD
Building Experience for Treating Trauma and Enhancing Resilience (BETTER)
Posttraumatic stress disorder (PTSD) is a significant problem among underserved populations who receive care in community health centers.
- Trial name
- BETTER (NCT05330442)
- Testing
- Written Exposure Therapy (WET)
- Where
- 10 sites in United States
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- RAND
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents
This study aims to examine the effectiveness of group Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT07325734
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive Group
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- Peking University
PTSD
Treatment for Antepartum Posttraumatic Stress Disorder/PTSD Study
The majority of women with perinatal posttraumatic stress disorder (PTSD) do not receive mental health treatment despite the documented associations between PTSD and adverse pregnancy outcomes; this is likely due to workforce…
- Trial name
- TAPS (NCT05486793)
- Testing
- Written Exposure Therapy (WET), Emotion Focused Supportive Therapy (EFST)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Boston University
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Extended Group Written Exposure Therapy for Comorbid PTSD and BPD (Traits)
The goal of this open label trial is to evaluate the effectiveness of virtual group extended Written Exposure Therapy (GE-WET) in reducing Post-Traumatic Stress Disorder (PTSD) symptoms in patients with comorbid PTSD and…
- Trial name
- NCT07576387
- Testing
- Group Written Exposure Therapy
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Substance Use Disorders, Posttraumatic Stress Disorder
Written Exposure Therapy for Veterans With SUD and PTSD
The proposed project will evaluate the efficacy of written exposure therapy (WET) among Veterans engaged in substance use disorder (SUD) treatment, who present with co-occurring posttraumatic stress disorder (PTSD).
- Trial name
- WET (NCT05327504)
- Testing
- Written Exposure Therapy, Neutral Topic Writing
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder (PTSD)
Examining Written Exposure Therapy Delivered to Adolescents
Written Exposure Therapy (WET) is a five-session mental health therapy for posttraumatic stress disorder (PTSD). Research shows that it works as well as longer treatments for PTSD among people over 18, even though it requires…
- Trial name
- NCT07498257
- Testing
- Written Exposure Therapy, Trauma-focused Cognitive Behavior Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Medical University of South Carolina